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Murcko scaffold

1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one scaffold

176 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
176
With full pages
12
Scaffold SMILES

O=c1cccc2n1CC1CNCC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one page
Murcko scaffold O=c1cccc2n1CC1CNCC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 176 chemicals

Cytisine chemical structure, C11H14N2O, CAS 485-35-8
Cytisine
CAS 485-35-8C11H14N2O
Cytisinium, N,N-dimethyl-, iodide chemical structure, C13H19IN2O, CAS 5853-05-4
Cytisinium, N,N-dimethyl-, iodide
CAS 5853-05-4C13H19IN2O
(-)-7R:9S-Cytisine hydrochloride chemical structure, C11H15ClN2O, CAS 744212-71-3
(-)-7R:9S-Cytisine hydrochloride
CAS 744212-71-3C11H15ClN2O
1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one chemical structure, C11H14N2O, CAS 15191-27-2
1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one
CAS 15191-27-2C11H14N2O
(1R,5S)-3-(3-Buten-1-yl)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one chemical structure, C15H20N2O, CAS 529-78-2
(1R,5S)-3-(3-Buten-1-yl)-1,2,3,4,5,6-hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one
CAS 529-78-2C15H20N2O
1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-methyl-4-(2-propenyl)- chemical structure, C15H20N2O, CAS 33530-05-1
1,5-Methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one, 1,2,3,4,5,6-hexahydro-3-methyl-4-(2-propenyl)-
CAS 33530-05-1C15H20N2O
N-Formylcytisine chemical structure, C12H14N2O2, CAS 53007-06-0
N-Formylcytisine
CAS 53007-06-0C12H14N2O2
Caulophylline chemical structure, C12H16N2O, CAS 63699-79-6
Caulophylline
CAS 63699-79-6C12H16N2O
Tinctorine chemical structure, C15H20N2O, CAS 33023-11-9
Tinctorine
CAS 33023-11-9C15H20N2O
N-Methylcytisine chemical structure, C12H16N2O, CAS 486-86-2
N-Methylcytisine
CAS 486-86-2C12H16N2O
(1S,5R)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one chemical structure, C11H14N2O, CAS 55821-72-2
(1S,5R)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido(1,2-a)(1,5)diazocin-8-one
CAS 55821-72-2C11H14N2O
N-{[(1S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]carbonyl}glycine chemical structure, C14H17N3O4, CAS 1212184-70-7
N-{[(1S)-8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]carbonyl}glycine
CAS 1212184-70-7C14H17N3O4
(S)-Methyl 3-methyl-2-((1R,5R)-8-oxo-2,3,4,5,6,8-hexahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3-carboxamido)butanoate chemical structure, C18H25N3O4, CAS 956777-93-8
(S)-Methyl 3-methyl-2-((1R,5R)-8-oxo-2,3,4,5,6,8-hexahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3-carboxamido)butanoate
CAS 956777-93-8C18H25N3O4
(S)-4-Methyl-2-((1R,5R)-8-oxo-2,3,4,5,6,8-hexahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3-carboxamido)pentanoic acid chemical structure, C18H25N3O4
(S)-4-Methyl-2-((1R,5R)-8-oxo-2,3,4,5,6,8-hexahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocine-3-carboxamido)pentanoic acid
C18H25N3O4
N-Acetylcytisine chemical structure, C13H16N2O2, CAS 6018-52-6
N-Acetylcytisine
CAS 6018-52-6C13H16N2O2
Methyl (1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-propanoate chemical structure, C15H20N2O3, CAS 5687-35-4
Methyl (1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-propanoate
CAS 5687-35-4C15H20N2O3
1,5-Methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-propanenitrile, 1,5,6,8-tetrahydro-8-oxo-, (1R)- chemical structure, C14H17N3O, CAS 5687-33-2
1,5-Methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-propanenitrile, 1,5,6,8-tetrahydro-8-oxo-, (1R)-
CAS 5687-33-2C14H17N3O
(1R,5S)-1,5,6,8-Tetrahydro-8-oxo-1,5-methano-2H-pyrido(1,2-a)(1,5)diazocine-3(4H)-acetamide chemical structure, C13H17N3O2, CAS 138867-34-2
(1R,5S)-1,5,6,8-Tetrahydro-8-oxo-1,5-methano-2H-pyrido(1,2-a)(1,5)diazocine-3(4H)-acetamide
CAS 138867-34-2C13H17N3O2
N-([(1S)-8-Oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]carbonyl)glycine chemical structure, C14H17N3O4, CAS 1820583-16-1
N-([(1S)-8-Oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl]carbonyl)glycine
CAS 1820583-16-1C14H17N3O4
1,5-Methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-acetic acid, 1,5,6,8-tetrahydro-8-oxo-, ethyl ester, (1R)- chemical structure, C15H20N2O3, CAS 99964-82-6
1,5-Methano-2H-pyrido[1,2-a][1,5]diazocine-3(4H)-acetic acid, 1,5,6,8-tetrahydro-8-oxo-, ethyl ester, (1R)-
CAS 99964-82-6C15H20N2O3
N-Nitrosocystisine chemical structure, C11H13N3O2, CAS 104759-77-5
N-Nitrosocystisine
CAS 104759-77-5C11H13N3O2
5-Oxo-5-{6-oxo-7,11-diazatricyclo[7.3.1.0,2,7]trideca-2,4-dien-11-yl}pentanoic acid chemical structure, C16H20N2O4, CAS 904261-70-7
5-Oxo-5-{6-oxo-7,11-diazatricyclo[7.3.1.0,2,7]trideca-2,4-dien-11-yl}pentanoic acid
CAS 904261-70-7C16H20N2O4
Cytisine, 12-methacryloyl- chemical structure, C15H18N2O2, CAS 32790-25-3
Cytisine, 12-methacryloyl-
CAS 32790-25-3C15H18N2O2
3-(Aminoacetyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one chemical structure, C13H17N3O2, CAS 15236-41-6
3-(Aminoacetyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one
CAS 15236-41-6C13H17N3O2