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Murcko scaffold

Ring system with 3 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
10
With full pages
2
Scaffold SMILES

O=C(NCc1ccccc1)c1cccc(C(=O)NCc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1cccc(C(=O)NCc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N~1~,N~3~-bis(4-chlorobenzyl)isophthalamide chemical structure, C22H18Cl2N2O2, CAS 449790-36-7
N~1~,N~3~-bis(4-chlorobenzyl)isophthalamide
CAS 449790-36-7C22H18Cl2N2O2
N~1~,N~3~-bis(2-methoxybenzyl)isophthalamide chemical structure, C24H24N2O4, CAS 330466-55-2
N~1~,N~3~-bis(2-methoxybenzyl)isophthalamide
CAS 330466-55-2C24H24N2O4
1-N,3-N-bis[(4-fluorophenyl)methyl]benzene-1,3-dicarboxamide chemical structure, C22H18F2N2O2, CAS 449790-52-7
1-N,3-N-bis[(4-fluorophenyl)methyl]benzene-1,3-dicarboxamide
CAS 449790-52-7C22H18F2N2O2
1-N,3-N-bis[(4-methoxyphenyl)methyl]benzene-1,3-dicarboxamide chemical structure, C24H24N2O4, CAS 349396-68-5
1-N,3-N-bis[(4-methoxyphenyl)methyl]benzene-1,3-dicarboxamide
CAS 349396-68-5C24H24N2O4
5-Nitro-1-N,3-N-bis(1-phenylethyl)benzene-1,3-dicarboxamide chemical structure, C24H23N3O4, CAS 294861-58-8
5-Nitro-1-N,3-N-bis(1-phenylethyl)benzene-1,3-dicarboxamide
CAS 294861-58-8C24H23N3O4
1-N,3-N-dibenzyl-1-N,3-N-diethylbenzene-1,3-dicarboxamide chemical structure, C26H28N2O2, CAS 349396-69-6
1-N,3-N-dibenzyl-1-N,3-N-diethylbenzene-1,3-dicarboxamide
CAS 349396-69-6C26H28N2O2
N1,N3-Bis(1-(4-methoxyphenyl)ethyl)isophthalamide chemical structure, C26H28N2O4, CAS 328281-56-7
N1,N3-Bis(1-(4-methoxyphenyl)ethyl)isophthalamide
CAS 328281-56-7C26H28N2O4
N~1~,N~3~-Dibenzyl-5-nitrobenzene-1,3-dicarboxamide chemical structure, C22H19N3O4, CAS 349408-65-7
N~1~,N~3~-Dibenzyl-5-nitrobenzene-1,3-dicarboxamide
CAS 349408-65-7C22H19N3O4
1-N,3-N-bis[(4-methoxyphenyl)methyl]-1-N,3-N-dimethylbenzene-1,3-dicarboxamide chemical structure, C26H28N2O4, CAS 401574-65-0
1-N,3-N-bis[(4-methoxyphenyl)methyl]-1-N,3-N-dimethylbenzene-1,3-dicarboxamide
CAS 401574-65-0C26H28N2O4
N~1~,N~3~-Bis[(1S)-2-hydroxy-1-phenylethyl]benzene-1,3-dicarboxamide chemical structure, C24H24N2O4, CAS 873654-25-2
N~1~,N~3~-Bis[(1S)-2-hydroxy-1-phenylethyl]benzene-1,3-dicarboxamide
CAS 873654-25-2C24H24N2O4