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Murcko scaffold

2-Phenylhexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione scaffold

34 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
34
With full pages
3
Scaffold SMILES

O=C1C2C3CCC(C3)C2C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenylhexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione page
Murcko scaffold O=C1C2C3CCC(C3)C2C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

4,7-Methano-1H-isoindole-1,3(2H)-dione, 5,6-dibromohexahydro-2-phenyl- chemical structure, C15H13Br2NO2, CAS 40703-79-5
4,7-Methano-1H-isoindole-1,3(2H)-dione, 5,6-dibromohexahydro-2-phenyl-
CAS 40703-79-5C15H13Br2NO2
2-Phenylhexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C15H15NO2, CAS 474376-63-1
2-Phenylhexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 474376-63-1C15H15NO2
2-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoic acid chemical structure, C16H15NO4, CAS 353524-19-3
2-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoic acid
CAS 353524-19-3C16H15NO4
3-(Octahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)benzoic acid chemical structure, C16H15NO4, CAS 353524-20-6
3-(Octahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)benzoic acid
CAS 353524-20-6C16H15NO4
4-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoic acid chemical structure, C16H15NO4, CAS 354158-53-5
4-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoic acid
CAS 354158-53-5C16H15NO4
2-[3-(Trifluoromethyl)phenyl]hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H14F3NO2, CAS 354158-56-8
2-[3-(Trifluoromethyl)phenyl]hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 354158-56-8C16H14F3NO2
Isobutyl 4-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate chemical structure, C20H23NO4, CAS 353524-23-9
Isobutyl 4-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate
CAS 353524-23-9C20H23NO4
Methyl 2-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate chemical structure, C17H17NO4, CAS 345952-84-3
Methyl 2-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate
CAS 345952-84-3C17H17NO4
5-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzene-1,3-dicarboxylic acid chemical structure, C17H15NO6, CAS 355412-64-5
5-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzene-1,3-dicarboxylic acid
CAS 355412-64-5C17H15NO6
2-(2-Methoxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H17NO3, CAS 353524-25-1
2-(2-Methoxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 353524-25-1C16H17NO3
2-[2-Chloro-5-(trifluoromethyl)phenyl]hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H13ClF3NO2, CAS 473801-39-7
2-[2-Chloro-5-(trifluoromethyl)phenyl]hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 473801-39-7C16H13ClF3NO2
Butyl 4-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate chemical structure, C20H23NO4, CAS 474377-05-4
Butyl 4-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate
CAS 474377-05-4C20H23NO4
2-(2,4-Dichlorophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C15H13Cl2NO2, CAS 474377-16-7
2-(2,4-Dichlorophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 474377-16-7C15H13Cl2NO2
2-(2-Hydroxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C15H15NO3, CAS 474377-34-9
2-(2-Hydroxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 474377-34-9C15H15NO3
2-(2,6-Dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C17H19NO2, CAS 474377-52-1
2-(2,6-Dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 474377-52-1C17H19NO2
2-(2-Ethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C17H19NO2, CAS 1005117-38-3
2-(2-Ethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005117-38-3C17H19NO2
4-{[4-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)phenyl]amino}-4-oxobutanoic acid chemical structure, C19H20N2O5, CAS 345951-36-2
4-{[4-(1,3-Dioxooctahydro-2H-4,7-methanoisoindol-2-yl)phenyl]amino}-4-oxobutanoic acid
CAS 345951-36-2C19H20N2O5
2-(2,3-Dichlorophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C15H13Cl2NO2, CAS 353524-35-3
2-(2,3-Dichlorophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 353524-35-3C15H13Cl2NO2
2-(4-Bromo-2,5-dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C17H18BrNO2, CAS 1005151-23-4
2-(4-Bromo-2,5-dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005151-23-4C17H18BrNO2
2-(4-Methyl-3-nitrophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H16N2O4, CAS 1005281-27-5
2-(4-Methyl-3-nitrophenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005281-27-5C16H16N2O4
2-(3-Chloro-2-methylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H16ClNO2, CAS 1005151-28-9
2-(3-Chloro-2-methylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005151-28-9C16H16ClNO2
2-(3-Methoxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C16H17NO3, CAS 1005281-64-0
2-(3-Methoxyphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005281-64-0C16H17NO3
2-(3,5-Dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione chemical structure, C17H19NO2, CAS 1005122-45-1
2-(3,5-Dimethylphenyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
CAS 1005122-45-1C17H19NO2
Ethyl 3-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate chemical structure, C18H19NO4, CAS 488785-74-6
Ethyl 3-(1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl)benzoate
CAS 488785-74-6C18H19NO4