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Murcko scaffold

4-Thiazolidinone, 3-phenyl-5-(2-thienylmethylene)-2-thioxo- scaffold

35 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
35
With full pages
5
Scaffold SMILES

O=C1C(=Cc2cccs2)SC(=S)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Thiazolidinone, 3-phenyl-5-(2-thienylmethylene)-2-thioxo- page
Murcko scaffold O=C1C(=Cc2cccs2)SC(=S)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

(Z)-4-(4-Oxo-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-3-yl)benzoic acid chemical structure, C15H9NO3S3, CAS 307504-96-7
(Z)-4-(4-Oxo-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-3-yl)benzoic acid
CAS 307504-96-7C15H9NO3S3
(5Z)-3-(4-Hydroxyphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C14H9NO2S3, CAS 306323-46-6
(5Z)-3-(4-Hydroxyphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 306323-46-6C14H9NO2S3
4-Thiazolidinone, 3-phenyl-5-(2-thienylmethylene)-2-thioxo- chemical structure, C14H9NOS3, CAS 151502-03-3
4-Thiazolidinone, 3-phenyl-5-(2-thienylmethylene)-2-thioxo-
CAS 151502-03-3C14H9NOS3
3-(4-Bromophenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C14H8BrNOS3, CAS 304863-95-4
3-(4-Bromophenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 304863-95-4C14H8BrNOS3
(Z)-3-(3,4-Dichlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H7Cl2NOS3, CAS 638139-65-8
(Z)-3-(3,4-Dichlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 638139-65-8C14H7Cl2NOS3
(Z)-3-(4-Fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H8FNOS3, CAS 301308-52-1
(Z)-3-(4-Fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 301308-52-1C14H8FNOS3
(Z)-3-(4-Chlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H8ClNOS3, CAS 309755-92-8
(Z)-3-(4-Chlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 309755-92-8C14H8ClNOS3
(Z)-3-(3,5-Dichlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H7Cl2NOS3, CAS 638139-63-6
(Z)-3-(3,5-Dichlorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 638139-63-6C14H7Cl2NOS3
3-(2-Methoxyphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C15H11NO2S3, CAS 307504-95-6
3-(2-Methoxyphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 307504-95-6C15H11NO2S3
3-(3-Methylphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C15H11NOS3, CAS 130685-96-0
3-(3-Methylphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 130685-96-0C15H11NOS3
(5Z)-3-(2-Methylphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C15H11NOS3, CAS 301305-40-8
(5Z)-3-(2-Methylphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 301305-40-8C15H11NOS3
(5E)-3-(2-Methylphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)thiazolidin-4-one chemical structure, C15H11NOS3, CAS 5634-53-7
(5E)-3-(2-Methylphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)thiazolidin-4-one
CAS 5634-53-7C15H11NOS3
(Z)-3-(2,3-Dimethylphenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C16H13NOS3, CAS 301305-41-9
(Z)-3-(2,3-Dimethylphenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 301305-41-9C16H13NOS3
(5Z)-5-(Thiophen-2-ylmethylidene)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-4-one chemical structure, C15H8F3NOS3, CAS 301308-46-3
(5Z)-5-(Thiophen-2-ylmethylidene)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-4-one
CAS 301308-46-3C15H8F3NOS3
(E)-3-(2-Ethoxyphenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C16H13NO2S3, CAS 638139-94-3
(E)-3-(2-Ethoxyphenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 638139-94-3C16H13NO2S3
3-(4-Ethoxy-phenyl)-5-thiophen-2-ylmethylene-2-thioxo-thiazolidin-4-one chemical structure, C16H13NO2S3, CAS 302562-39-6
3-(4-Ethoxy-phenyl)-5-thiophen-2-ylmethylene-2-thioxo-thiazolidin-4-one
CAS 302562-39-6C16H13NO2S3
(Z)-3-(2-Fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H8FNOS3, CAS 638139-53-4
(Z)-3-(2-Fluorophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 638139-53-4C14H8FNOS3
3-(3-Methoxyphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C15H11NO2S3, CAS 306323-85-3
3-(3-Methoxyphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 306323-85-3C15H11NO2S3
3-[4-(Diethylamino)phenyl]-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C18H18N2OS3, CAS 1164524-33-7
3-[4-(Diethylamino)phenyl]-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 1164524-33-7C18H18N2OS3
(5Z)-3-(3-Hydroxyphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-4-one chemical structure, C14H9NO2S3, CAS 307342-78-5
(5Z)-3-(3-Hydroxyphenyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-4-one
CAS 307342-78-5C14H9NO2S3
3-(3,4-Dimethylphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C16H13NOS3, CAS 307342-87-6
3-(3,4-Dimethylphenyl)-5-(2-thienylmethylene)-2-thioxo-1,3-thiazolidin-4-one
CAS 307342-87-6C16H13NOS3
(5Z)-3-(4-Methylphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C15H11NOS3, CAS 324565-20-0
(5Z)-3-(4-Methylphenyl)-5-(thiophen-2-ylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
CAS 324565-20-0C15H11NOS3
(Z)-3-(2-Bromophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H8BrNOS3, CAS 638139-25-0
(Z)-3-(2-Bromophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 638139-25-0C14H8BrNOS3
(Z)-3-(3-Bromophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one chemical structure, C14H8BrNOS3, CAS 418803-25-5
(Z)-3-(3-Bromophenyl)-5-(thiophen-2-ylmethylene)-2-thioxothiazolidin-4-one
CAS 418803-25-5C14H8BrNOS3