CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

64 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
64
With full pages
6
Scaffold SMILES

O=C1NC(=O)C(=Cc2ccc(-c3ccccc3)o2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(=Cc2ccc(-c3ccccc3)o2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

(E)-5-((5-(4-Fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione chemical structure, C14H8FNO3S, CAS 1218777-13-9
(E)-5-((5-(4-Fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione
CAS 1218777-13-9C14H8FNO3S
(E)-5-((5-(2,3-Dichlorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione chemical structure, C14H7Cl2NO3S, CAS 1218777-14-0
(E)-5-((5-(2,3-Dichlorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione
CAS 1218777-14-0C14H7Cl2NO3S
IGF-1R inhibitor-5 chemical structure, C14H7Cl2NO3S, CAS 331652-38-1
IGF-1R inhibitor-5
CAS 331652-38-1C14H7Cl2NO3S
5-{[5-(3,4-Dichlorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione chemical structure, C14H7Cl2NO3S, CAS 1218777-18-4
5-{[5-(3,4-Dichlorophenyl)-2-furyl]methylene}-1,3-thiazolidine-2,4-dione
CAS 1218777-18-4C14H7Cl2NO3S
(5E)-5-[[5-(5-Chloro-2-methylphenyl)furan-2-yl]methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione chemical structure, C18H12ClNO3S, CAS 432532-14-4
(5E)-5-[[5-(5-Chloro-2-methylphenyl)furan-2-yl]methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione
CAS 432532-14-4C18H12ClNO3S
5-[5-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-hydroxybenzoic acid chemical structure, C15H9NO6S, CAS 313394-27-3
5-[5-[(Z)-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-hydroxybenzoic acid
CAS 313394-27-3C15H9NO6S
2-Chloro-5-[5-(2,4-dioxo-thiazolidin-5-ylidenemethyl)-furan-2-yl]-benzoic acid methyl ester chemical structure, C16H10ClNO5S, CAS 591745-18-5
2-Chloro-5-[5-(2,4-dioxo-thiazolidin-5-ylidenemethyl)-furan-2-yl]-benzoic acid methyl ester
CAS 591745-18-5C16H10ClNO5S
(5E)-5-{[5-(4-Chloro-3-nitrophenyl)furan-2-yl]methylidene}-1,3-thiazolidine-2,4-dione chemical structure, C14H7ClN2O5S, CAS 327033-04-5
(5E)-5-{[5-(4-Chloro-3-nitrophenyl)furan-2-yl]methylidene}-1,3-thiazolidine-2,4-dione
CAS 327033-04-5C14H7ClN2O5S
(5E)-5-[[5-(4-Methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione chemical structure, C18H14N2O5S, CAS 593274-03-4
(5E)-5-[[5-(4-Methyl-3-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione
CAS 593274-03-4C18H14N2O5S
(5E)-5-[[5-(2-Methoxy-4-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione chemical structure, C18H14N2O6S, CAS 593265-80-6
(5E)-5-[[5-(2-Methoxy-4-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-enyl-1,3-thiazolidine-2,4-dione
CAS 593265-80-6C18H14N2O6S
4-(5-{(E)-[3-(2-Methoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-methylbenzoic acid chemical structure, C19H15NO7S, CAS 690686-89-6
4-(5-{(E)-[3-(2-Methoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-methylbenzoic acid
CAS 690686-89-6C19H15NO7S
4-Chloro-3-[5-[[3-(2-ethoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acid chemical structure, C19H14ClNO7S
4-Chloro-3-[5-[[3-(2-ethoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]benzoic acid
C19H14ClNO7S
(5E)-5-[[5-(2-Methoxy-5-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione chemical structure, C18H12N2O6S, CAS 432020-57-0
(5E)-5-[[5-(2-Methoxy-5-nitrophenyl)furan-2-yl]methylidene]-3-prop-2-ynyl-1,3-thiazolidine-2,4-dione
CAS 432020-57-0C18H12N2O6S
Ethyl {5-[(5-{4-chloro-2-nitrophenyl}-2-furyl)methylene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate chemical structure, C18H13ClN2O7S, CAS 432523-52-9
Ethyl {5-[(5-{4-chloro-2-nitrophenyl}-2-furyl)methylene]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate
CAS 432523-52-9C18H13ClN2O7S
3-[5-[(Z)-[3-(2-Ethoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-2-methylbenzoic acid chemical structure, C20H17NO7S, CAS 444785-04-0
3-[5-[(Z)-[3-(2-Ethoxy-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-2-methylbenzoic acid
CAS 444785-04-0C20H17NO7S
2-Chloro-4-(5-{(E)-[2,4-dioxo-3-(prop-2-en-1-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid chemical structure, C18H12ClNO5S, CAS 664356-93-8
2-Chloro-4-(5-{(E)-[2,4-dioxo-3-(prop-2-en-1-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid
CAS 664356-93-8C18H12ClNO5S
3-{5-[(3-Ethyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-2-methylbenzoic acid chemical structure, C18H15NO5S, CAS 593274-23-8
3-{5-[(3-Ethyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]-2-furyl}-2-methylbenzoic acid
CAS 593274-23-8C18H15NO5S
(E)-5-((5-(2,5-Dichlorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione chemical structure, C14H7Cl2NO3S, CAS 365982-24-7
(E)-5-((5-(2,5-Dichlorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione
CAS 365982-24-7C14H7Cl2NO3S
4-(5-{(Z)-[2,4-Dioxo-3-(prop-2-yn-1-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-methylbenzoic acid chemical structure, C19H13NO5S, CAS 444694-49-9
4-(5-{(Z)-[2,4-Dioxo-3-(prop-2-yn-1-yl)-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-3-methylbenzoic acid
CAS 444694-49-9C19H13NO5S
(E)-2-Chloro-4-(5-((3-(2-methoxy-2-oxoethyl)-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid chemical structure, C18H12ClNO7S, CAS 593272-19-6
(E)-2-Chloro-4-(5-((3-(2-methoxy-2-oxoethyl)-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic acid
CAS 593272-19-6C18H12ClNO7S
Methyl (Z)-2-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoate chemical structure, C16H11NO5S, CAS 900515-01-7
Methyl (Z)-2-(5-((2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoate
CAS 900515-01-7C16H11NO5S
Methyl [(5E)-5-{[5-(2-methoxy-5-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate chemical structure, C18H14N2O8S, CAS 690686-59-0
Methyl [(5E)-5-{[5-(2-methoxy-5-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate
CAS 690686-59-0C18H14N2O8S
Methyl [(5E)-5-{[5-(2-methoxy-4-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate chemical structure, C18H14N2O8S, CAS 690686-93-2
Methyl [(5E)-5-{[5-(2-methoxy-4-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate
CAS 690686-93-2C18H14N2O8S
Methyl [(5E)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate chemical structure, C17H11ClN2O7S, CAS 690693-68-6
Methyl [(5E)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]methylidene}-2,4-dioxo-1,3-thiazolidin-3-yl]acetate
CAS 690693-68-6C17H11ClN2O7S