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Murcko scaffold

Ring system with 3 rings and 19 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
9
With full pages
4
Scaffold SMILES

O=C1NN(c2ccccc2)C(=O)C1=Cc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NN(c2ccccc2)C(=O)C1=Cc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(4Z)-1-(4-Bromophenyl)-4-(furan-2-ylmethylidene)pyrazolidine-3,5-dione chemical structure, C14H9BrN2O3, CAS 330965-67-8
(4Z)-1-(4-Bromophenyl)-4-(furan-2-ylmethylidene)pyrazolidine-3,5-dione
CAS 330965-67-8C14H9BrN2O3
(4Z)-4-(Furan-2-ylmethylidene)-1-phenylpyrazolidine-3,5-dione chemical structure, C14H10N2O3, CAS 5562-25-4
(4Z)-4-(Furan-2-ylmethylidene)-1-phenylpyrazolidine-3,5-dione
CAS 5562-25-4C14H10N2O3
(4Z)-4-(Furan-2-ylmethylidene)-1-(4-methylphenyl)pyrazolidine-3,5-dione chemical structure, C15H12N2O3, CAS 418804-46-3
(4Z)-4-(Furan-2-ylmethylidene)-1-(4-methylphenyl)pyrazolidine-3,5-dione
CAS 418804-46-3C15H12N2O3
1-(3,4-Dimethylphenyl)-4-(2-furanylmethylene)-3,5-pyrazolidinedione chemical structure, C16H14N2O3, CAS 327981-29-3
1-(3,4-Dimethylphenyl)-4-(2-furanylmethylene)-3,5-pyrazolidinedione
CAS 327981-29-3C16H14N2O3
Pyr-41 chemical structure, C17H13N3O7, CAS 418805-02-4
Pyr-41
CAS 418805-02-4C17H13N3O7
(4E)-4-[(5-Bromofuran-2-yl)methylidene]-1-phenylpyrazolidine-3,5-dione chemical structure, C14H9BrN2O3, CAS 423746-84-3
(4E)-4-[(5-Bromofuran-2-yl)methylidene]-1-phenylpyrazolidine-3,5-dione
CAS 423746-84-3C14H9BrN2O3
1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furyl)methylene]-3,5-pyrazolidinedione chemical structure, C14H7ClFN3O5, CAS 423148-78-1
1-(3-Chloro-4-fluorophenyl)-4-[(5-nitro-2-furyl)methylene]-3,5-pyrazolidinedione
CAS 423148-78-1C14H7ClFN3O5
(4E)-1-(3-Chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione chemical structure, C14H7ClFN3O5
(4E)-1-(3-Chloro-4-fluorophenyl)-4-[(5-nitrofuran-2-yl)methylidene]pyrazolidine-3,5-dione
C14H7ClFN3O5
(E)-1-(3-Chloro-4-fluorophenyl)-4-((5-nitrofuran-2-yl)methylene)pyrazolidine-3,5-dione chemical structure, C14H7ClFN3O5
(E)-1-(3-Chloro-4-fluorophenyl)-4-((5-nitrofuran-2-yl)methylene)pyrazolidine-3,5-dione
C14H7ClFN3O5