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Murcko scaffold

Ring system with 2 rings and 10 atoms

44 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
44
With full pages
9
Scaffold SMILES

c1csc(-c2ncco2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2ncco2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

5-(2-Methylpropylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile chemical structure, C12H13N3OS, CAS 613650-07-0
5-(2-Methylpropylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile
CAS 613650-07-0C12H13N3OS
5-Ethoxy-2-(2-thienyl)-1,3-oxazole chemical structure, C9H9NO2S, CAS 284040-86-4
5-Ethoxy-2-(2-thienyl)-1,3-oxazole
CAS 284040-86-4C9H9NO2S
5-(Allylamino)-2-(2-thienyl)-1,3-oxazole-4-carbonitrile chemical structure, C11H9N3OS, CAS 613650-10-5
5-(Allylamino)-2-(2-thienyl)-1,3-oxazole-4-carbonitrile
CAS 613650-10-5C11H9N3OS
5-(2-Methoxyethylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile chemical structure, C11H11N3O2S, CAS 613650-05-8
5-(2-Methoxyethylamino)-2-thiophen-2-yl-1,3-oxazole-4-carbonitrile
CAS 613650-05-8C11H11N3O2S
4-(Chloromethyl)-2-(thiophen-2-yl)-1,3-oxazole chemical structure, C8H6ClNOS, CAS 54679-74-2
4-(Chloromethyl)-2-(thiophen-2-yl)-1,3-oxazole
CAS 54679-74-2C8H6ClNOS
4,5-Dimethyl-2-(thiophen-2-yl)oxazole 3-oxide chemical structure, C9H9NO2S, CAS 37151-22-7
4,5-Dimethyl-2-(thiophen-2-yl)oxazole 3-oxide
CAS 37151-22-7C9H9NO2S
5-Hydrazinyl-2-(thiophen-2-yl)-1,3-oxazole-4-carbonitrile chemical structure, C8H6N4OS, CAS 890013-94-2
5-Hydrazinyl-2-(thiophen-2-yl)-1,3-oxazole-4-carbonitrile
CAS 890013-94-2C8H6N4OS
4-(Chloromethyl)-5-methyl-2-(thiophen-2-yl)-1,3-oxazole chemical structure, C9H8ClNOS, CAS 202595-63-9
4-(Chloromethyl)-5-methyl-2-(thiophen-2-yl)-1,3-oxazole
CAS 202595-63-9C9H8ClNOS
[2-(Thiophen-2-yl)-1,3-oxazol-4-yl]methanamine chemical structure, C8H8N2OS, CAS 923213-51-8
[2-(Thiophen-2-yl)-1,3-oxazol-4-yl]methanamine
CAS 923213-51-8C8H8N2OS
5-Methyl-2-(thiophen-2-yl)oxazole chemical structure, C8H7NOS, CAS 146896-55-1
5-Methyl-2-(thiophen-2-yl)oxazole
CAS 146896-55-1C8H7NOS
2-(5-Methyl-2-(thiophen-2-yl)oxazol-4-yl)ethan-1-ol chemical structure, C10H11NO2S, CAS 403611-90-5
2-(5-Methyl-2-(thiophen-2-yl)oxazol-4-yl)ethan-1-ol
CAS 403611-90-5C10H11NO2S
2-(Thiophen-2-yl)oxazole-5-carbaldehyde chemical structure, C8H5NO2S, CAS 106833-78-7
2-(Thiophen-2-yl)oxazole-5-carbaldehyde
CAS 106833-78-7C8H5NO2S
2-(2-Thienyl)-5-oxazolecarboxylic acid chemical structure, C8H5NO3S, CAS 106833-80-1
2-(2-Thienyl)-5-oxazolecarboxylic acid
CAS 106833-80-1C8H5NO3S
5-Ethoxy-2-(thiophen-2-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C10H9NO4S, CAS 923710-57-0
5-Ethoxy-2-(thiophen-2-yl)-1,3-oxazole-4-carboxylic acid
CAS 923710-57-0C10H9NO4S
2-(5-Methyl-2-(thiophen-2-yl)-1,3-oxazol-4-yl)acetic acid chemical structure, C10H9NO3S, CAS 403611-88-1
2-(5-Methyl-2-(thiophen-2-yl)-1,3-oxazol-4-yl)acetic acid
CAS 403611-88-1C10H9NO3S
(2-(Thiophen-2-yl)oxazol-4-yl)methanamine hydrochloride chemical structure, C8H9ClN2OS, CAS 1049731-26-1
(2-(Thiophen-2-yl)oxazol-4-yl)methanamine hydrochloride
CAS 1049731-26-1C8H9ClN2OS
5-Methyl-2-(thiophen-2-yl)-1,3-oxazole-4-carboxylic acid chemical structure, C9H7NO3S, CAS 1016526-89-8
5-Methyl-2-(thiophen-2-yl)-1,3-oxazole-4-carboxylic acid
CAS 1016526-89-8C9H7NO3S
Ethyl 5-Methyl-2-(2-thienyl)oxazole-4-carboxylate chemical structure, C11H11NO3S, CAS 51655-74-4
Ethyl 5-Methyl-2-(2-thienyl)oxazole-4-carboxylate
CAS 51655-74-4C11H11NO3S
2-[5-Methyl-2-(thiophen-2-yl)-1,3-oxazol-4-yl]acetonitrile chemical structure, C10H8N2OS, CAS 403611-87-0
2-[5-Methyl-2-(thiophen-2-yl)-1,3-oxazol-4-yl]acetonitrile
CAS 403611-87-0C10H8N2OS
2-(5-Methyl-2-(5-methylthiophen-2-yl)oxazol-4-yl)acetic acid chemical structure, C11H11NO3S, CAS 401791-29-5
2-(5-Methyl-2-(5-methylthiophen-2-yl)oxazol-4-yl)acetic acid
CAS 401791-29-5C11H11NO3S
4-(Chloromethyl)-5-methyl-2-(5-methylthiophen-2-yl)-1,3-oxazole chemical structure, C10H10ClNOS, CAS 866641-11-4
4-(Chloromethyl)-5-methyl-2-(5-methylthiophen-2-yl)-1,3-oxazole
CAS 866641-11-4C10H10ClNOS
2-[2-(Thiophen-2-yl)-1,3-oxazol-4-yl]acetonitrile chemical structure, C9H6N2OS, CAS 949980-44-3
2-[2-(Thiophen-2-yl)-1,3-oxazol-4-yl]acetonitrile
CAS 949980-44-3C9H6N2OS
5-Methyl-2-(thiophen-2-yl)oxazole-4-carbaldehyde chemical structure, C9H7NO2S, CAS 915923-87-4
5-Methyl-2-(thiophen-2-yl)oxazole-4-carbaldehyde
CAS 915923-87-4C9H7NO2S
2-(2-(Thiophen-2-yl)-1,3-oxazol-4-yl)acetic acid chemical structure, C9H7NO3S, CAS 1082414-36-5
2-(2-(Thiophen-2-yl)-1,3-oxazol-4-yl)acetic acid
CAS 1082414-36-5C9H7NO3S