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Murcko scaffold

Ring system with 2 rings and 10 atoms

175 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
175
With full pages
30
Scaffold SMILES

c1ncc(B2OCCO2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ncc(B2OCCO2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 175 chemicals

2-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C9H13BClNO2S, CAS 889672-72-4
2-Chloro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 889672-72-4C9H13BClNO2S
2,4-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C11H18BNO2S, CAS 859833-13-9
2,4-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 859833-13-9C11H18BNO2S
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C10H16BNO3S, CAS 1312765-17-5
2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1312765-17-5C10H16BNO3S
2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C11H18BNO3S, CAS 2096338-64-4
2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2096338-64-4C11H18BNO3S
2-Isopropoxy-1,3-thiazole-5-boronic acid, pinacol ester chemical structure, C12H20BNO3S, CAS 1352652-22-2
2-Isopropoxy-1,3-thiazole-5-boronic acid, pinacol ester
CAS 1352652-22-2C12H20BNO3S
2-(N-Propoxy)thiazole-5-boronic acid pinacol ester chemical structure, C12H20BNO3S, CAS 2096329-92-7
2-(N-Propoxy)thiazole-5-boronic acid pinacol ester
CAS 2096329-92-7C12H20BNO3S
2-(tert-Butoxy)thiazole-5-boronic acid pinacol ester chemical structure, C13H22BNO3S, CAS 1416719-94-2
2-(tert-Butoxy)thiazole-5-boronic acid pinacol ester
CAS 1416719-94-2C13H22BNO3S
2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C10H16BNO2S, CAS 1218791-01-5
2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1218791-01-5C10H16BNO2S
2-(Methyl-d3)-thiazole-5-boronic acid pinacol ester chemical structure, C10H16BNO2S, CAS 2241876-29-7
2-(Methyl-d3)-thiazole-5-boronic acid pinacol ester
CAS 2241876-29-7C10H16BNO2S
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine chemical structure, C9H15BN2O2S, CAS 1446485-98-8
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-amine
CAS 1446485-98-8C9H15BN2O2S
2-(tert-Butyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H22BNO2S, CAS 1426089-85-1
2-(tert-Butyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1426089-85-1C13H22BNO2S
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C9H14BNO2S, CAS 1086111-09-2
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1086111-09-2C9H14BNO2S
2-Propyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO2S, CAS 2223052-84-2
2-Propyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2223052-84-2C12H20BNO2S
2-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO2S, CAS 1446481-20-4
2-Isopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1446481-20-4C12H20BNO2S
2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C11H18BNO2S, CAS 1446478-67-6
2-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1446478-67-6C11H18BNO2S
tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)((2-(trimethylsilyl)ethoxy)methyl)carbamate chemical structure, C20H37BN2O5SSi, CAS 1228356-82-8
tert-Butyl (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)((2-(trimethylsilyl)ethoxy)methyl)carbamate
CAS 1228356-82-8C20H37BN2O5SSi
2-(Triisopropylsilyl)thiazole-5-boronic acid pinacol ester chemical structure, C18H34BNO2SSi, CAS 1175534-91-4
2-(Triisopropylsilyl)thiazole-5-boronic acid pinacol ester
CAS 1175534-91-4C18H34BNO2SSi
2-Isopropyl-4-methylthiazole-5-boronic acid, pinacol ester chemical structure, C13H22BNO2S, CAS 1218789-55-9
2-Isopropyl-4-methylthiazole-5-boronic acid, pinacol ester
CAS 1218789-55-9C13H22BNO2S
2-Ethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H20BNO2S, CAS 1218789-94-6
2-Ethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1218789-94-6C12H20BNO2S
2-Methoxy-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C11H18BNO3S, CAS 1312762-47-2
2-Methoxy-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 1312762-47-2C11H18BNO3S
tert-Butyl isopropyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)carbamate chemical structure, C17H29BN2O4S, CAS 905300-51-8
tert-Butyl isopropyl(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazol-2-yl)carbamate
CAS 905300-51-8C17H29BN2O4S
2-Acetoxythiazole-5-boronic acid pinacol ester chemical structure, C11H16BNO4S, CAS 1350755-64-4
2-Acetoxythiazole-5-boronic acid pinacol ester
CAS 1350755-64-4C11H16BNO4S
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole-2-carboxylate chemical structure, C11H16BNO4S, CAS 1393827-96-7
Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole-2-carboxylate
CAS 1393827-96-7C11H16BNO4S
2-(Methylsulfanyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C10H16BNO2S2, CAS 2096331-12-1
2-(Methylsulfanyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 2096331-12-1C10H16BNO2S2