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Murcko scaffold

5-(2-Thienyl)pyrazole scaffold

672 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
672
With full pages
35
Scaffold SMILES

c1csc(-c2cc[nH]n2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(2-Thienyl)pyrazole page
Murcko scaffold c1csc(-c2cc[nH]n2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 672 chemicals

N-Methyl-N-[[3-thiophen-2-yl-5-(trifluoromethyl)-1H-pyrazol-4-yl]diazenyl]methanamine chemical structure, C10H10F3N5S, CAS 27218-44-6
N-Methyl-N-[[3-thiophen-2-yl-5-(trifluoromethyl)-1H-pyrazol-4-yl]diazenyl]methanamine
CAS 27218-44-6C10H10F3N5S
N,N,N'-Trimethyl-N'-[[3-thiophen-2-yl-5-(trifluoromethyl)-1H-pyrazol-4-yl]diazenyl]ethane-1,2-diamine chemical structure, C13H17F3N6S, CAS 27218-48-0
N,N,N'-Trimethyl-N'-[[3-thiophen-2-yl-5-(trifluoromethyl)-1H-pyrazol-4-yl]diazenyl]ethane-1,2-diamine
CAS 27218-48-0C13H17F3N6S
5-(2-Thienyl)pyrazole chemical structure, C7H6N2S, CAS 219863-71-5
5-(2-Thienyl)pyrazole
CAS 219863-71-5C7H6N2S
3-(Thiophen-2-yl)-1H-pyrazol-5-amine chemical structure, C7H7N3S, CAS 96799-03-0
3-(Thiophen-2-yl)-1H-pyrazol-5-amine
CAS 96799-03-0C7H7N3S
5-(2-Thienyl)-3-(trifluoromethyl)-1H-pyrazole chemical structure, C8H5F3N2S, CAS 26974-16-3
5-(2-Thienyl)-3-(trifluoromethyl)-1H-pyrazole
CAS 26974-16-3C8H5F3N2S
3-(Thiophen-2-yl)-1H-pyrazole-4-carbaldehyde chemical structure, C8H6N2OS, CAS 26033-27-2
3-(Thiophen-2-yl)-1H-pyrazole-4-carbaldehyde
CAS 26033-27-2C8H6N2OS
3-Methyl-5-(2-thienyl)-1H-pyrazole chemical structure, C8H8N2S, CAS 31618-80-1
3-Methyl-5-(2-thienyl)-1H-pyrazole
CAS 31618-80-1C8H8N2S
5-(Thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chemical structure, C8H6N2O2S, CAS 182415-24-3
5-(Thiophen-2-yl)-1H-pyrazole-3-carboxylic acid
CAS 182415-24-3C8H6N2O2S
3-(5-Chlorothiophen-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C8H7ClN4OS, CAS 634890-18-9
3-(5-Chlorothiophen-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 634890-18-9C8H7ClN4OS
5-(5-Bromothiophen-2-yl)-1H-pyrazole-3-carbohydrazide chemical structure, C8H7BrN4OS, CAS 634890-31-6
5-(5-Bromothiophen-2-yl)-1H-pyrazole-3-carbohydrazide
CAS 634890-31-6C8H7BrN4OS
5-(2-Thienyl)-1H-pyrazole-3-carboxylic acid hydrazide chemical structure, C8H8N4OS, CAS 92352-25-5
5-(2-Thienyl)-1H-pyrazole-3-carboxylic acid hydrazide
CAS 92352-25-5C8H8N4OS
1-Methyl-3-(2-thienyl)-1H-pyrazole chemical structure, C8H8N2S, CAS 477708-76-2
1-Methyl-3-(2-thienyl)-1H-pyrazole
CAS 477708-76-2C8H8N2S
5-(3-Bromothiophen-2-yl)-1H-pyrazole chemical structure, C7H5BrN2S, CAS 166196-68-5
5-(3-Bromothiophen-2-yl)-1H-pyrazole
CAS 166196-68-5C7H5BrN2S
5-(3-Chloro-2-thienyl)-1H-pyrazole chemical structure, C7H5ClN2S, CAS 166196-59-4
5-(3-Chloro-2-thienyl)-1H-pyrazole
CAS 166196-59-4C7H5ClN2S
5-(3-Chloro-2-thienyl)-1-[(trifluoromethyl)sulfonyl]-1H-pyrazole chemical structure, C8H4ClF3N2O2S2, CAS 318951-83-6
5-(3-Chloro-2-thienyl)-1-[(trifluoromethyl)sulfonyl]-1H-pyrazole
CAS 318951-83-6C8H4ClF3N2O2S2
3-(4-Formyl-3-thien-2-yl-1H-pyrazol-1-yl)propanenitrile chemical structure, C11H9N3OS, CAS 372107-06-7
3-(4-Formyl-3-thien-2-yl-1H-pyrazol-1-yl)propanenitrile
CAS 372107-06-7C11H9N3OS
1-(2-Cyanoethyl)-3-thiophen-2-ylpyrazole-4-carboxylic acid chemical structure, C11H9N3O2S, CAS 956984-76-2
1-(2-Cyanoethyl)-3-thiophen-2-ylpyrazole-4-carboxylic acid
CAS 956984-76-2C11H9N3O2S
1-(2-Cyanoethyl)-3-thiophen-2-ylpyrazole-4-carboxamide chemical structure, C11H10N4OS, CAS 956352-42-4
1-(2-Cyanoethyl)-3-thiophen-2-ylpyrazole-4-carboxamide
CAS 956352-42-4C11H10N4OS
1-(Diaminomethylidene)-2-(5-thiophen-2-yl-1H-pyrazol-3-yl)guanidine chemical structure, C9H11N7S, CAS 4775-07-9
1-(Diaminomethylidene)-2-(5-thiophen-2-yl-1H-pyrazol-3-yl)guanidine
CAS 4775-07-9C9H11N7S
1-Methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine chemical structure, C8H9N3S, CAS 118430-78-7
1-Methyl-3-(thiophen-2-yl)-1H-pyrazol-5-amine
CAS 118430-78-7C8H9N3S
5-(5-Bromothiophen-2-yl)-1H-pyrazole chemical structure, C7H5BrN2S, CAS 166196-67-4
5-(5-Bromothiophen-2-yl)-1H-pyrazole
CAS 166196-67-4C7H5BrN2S
5-(5-Chloro-2-thienyl)-1H-pyrazole chemical structure, C7H5ClN2S, CAS 166196-61-8
5-(5-Chloro-2-thienyl)-1H-pyrazole
CAS 166196-61-8C7H5ClN2S
Ethyl 3-(thien-2-yl)-1H-pyrazole-5-carboxylate chemical structure, C10H10N2O2S, CAS 121195-03-7
Ethyl 3-(thien-2-yl)-1H-pyrazole-5-carboxylate
CAS 121195-03-7C10H10N2O2S
5-(1H-Pyrazol-5-yl)thiophene-2-sulfonyl chloride chemical structure, C7H5ClN2O2S2, CAS 1030288-73-3
5-(1H-Pyrazol-5-yl)thiophene-2-sulfonyl chloride
CAS 1030288-73-3C7H5ClN2O2S2