CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 10 atoms

166 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
166
With full pages
23
Scaffold SMILES

c1csc(-c2cscn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(-c2cscn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 166 chemicals

Arotinolol chemical structure, C15H21N3O2S3, CAS 68377-92-4
Arotinolol
CAS 68377-92-4C15H21N3O2S3
Formamide, N-(4-(5-nitro-2-thienyl)-2-thiazolyl)- chemical structure, C8H5N3O3S2, CAS 58139-46-1
Formamide, N-(4-(5-nitro-2-thienyl)-2-thiazolyl)-
CAS 58139-46-1C8H5N3O3S2
Formamide, N-(4-(4-nitro-2-thienyl)-2-thiazolyl)- chemical structure, C8H5N3O3S2, CAS 58139-52-9
Formamide, N-(4-(4-nitro-2-thienyl)-2-thiazolyl)-
CAS 58139-52-9C8H5N3O3S2
Acetamide, N-(4-(4-nitro-2-thienyl)-2-thiazolyl)- chemical structure, C9H7N3O3S2, CAS 58139-53-0
Acetamide, N-(4-(4-nitro-2-thienyl)-2-thiazolyl)-
CAS 58139-53-0C9H7N3O3S2
N-(4-(5-Nitro-2-thienyl)-2-thiazolyl)acetamide chemical structure, C9H7N3O3S2, CAS 34800-28-7
N-(4-(5-Nitro-2-thienyl)-2-thiazolyl)acetamide
CAS 34800-28-7C9H7N3O3S2
4-(5-Nitro-2-thienyl)-2-thiazolamine chemical structure, C7H5N3O2S2, CAS 34801-16-6
4-(5-Nitro-2-thienyl)-2-thiazolamine
CAS 34801-16-6C7H5N3O2S2
4-(4-Nitrothiophen-2-yl)thiazol-2-amine chemical structure, C7H5N3O2S2, CAS 58139-51-8
4-(4-Nitrothiophen-2-yl)thiazol-2-amine
CAS 58139-51-8C7H5N3O2S2
Arotinolol hydrochloride chemical structure, C15H22ClN3O2S3, CAS 68377-91-3
Arotinolol hydrochloride
CAS 68377-91-3C15H22ClN3O2S3
4-(2-Thienyl)-1,3-thiazol-2-amine chemical structure, C7H6N2S2, CAS 28989-50-6
4-(2-Thienyl)-1,3-thiazol-2-amine
CAS 28989-50-6C7H6N2S2
5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid chemical structure, C9H7NO2S2, CAS 400715-45-9
5-(2-Methyl-1,3-thiazol-4-yl)thiophene-2-carboxylic acid
CAS 400715-45-9C9H7NO2S2
Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)- chemical structure, C7H4Cl2N2S2, CAS 959042-70-7
Thiazol-2-amine, 4-(4,5-dichloro-2-thienyl)-
CAS 959042-70-7C7H4Cl2N2S2
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C9H8N2OS2, CAS 34800-25-4
N-[4-(Thiophen-2-yl)-1,3-thiazol-2-yl]acetamide
CAS 34800-25-4C9H8N2OS2
4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C7H5ClN2S2, CAS 123971-45-9
4-(5-Chlorothiophen-2-yl)-1,3-thiazol-2-amine
CAS 123971-45-9C7H5ClN2S2
4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C7H5BrN2S2, CAS 34801-14-4
4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-amine
CAS 34801-14-4C7H5BrN2S2
2-Methyl-4-(2-thienyl)-1,3-thiazole chemical structure, C8H7NS2, CAS 21036-67-9
2-Methyl-4-(2-thienyl)-1,3-thiazole
CAS 21036-67-9C8H7NS2
5-Methyl-4-(2-thienyl)-1,3-thiazol-2-amine chemical structure, C8H8N2S2, CAS 206555-52-4
5-Methyl-4-(2-thienyl)-1,3-thiazol-2-amine
CAS 206555-52-4C8H8N2S2
N-(2-Amino-4-(2-thienyl)-1,3-thiazol-5-yl)acetamide chemical structure, C9H9N3OS2, CAS 518350-11-3
N-(2-Amino-4-(2-thienyl)-1,3-thiazol-5-yl)acetamide
CAS 518350-11-3C9H9N3OS2
4-(5-Ethylthiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C9H10N2S2, CAS 524932-70-5
4-(5-Ethylthiophen-2-yl)-1,3-thiazol-2-amine
CAS 524932-70-5C9H10N2S2
N-[4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C9H7BrN2OS2, CAS 34800-26-5
N-[4-(5-Bromothiophen-2-yl)-1,3-thiazol-2-yl]acetamide
CAS 34800-26-5C9H7BrN2OS2
2-[2-Methyl-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetic acid chemical structure, C10H9NO2S2, CAS 314032-13-8
2-[2-Methyl-4-(thiophen-2-yl)-1,3-thiazol-5-yl]acetic acid
CAS 314032-13-8C10H9NO2S2
2-(4-(Thiophen-2-yl)thiazol-2-yl)acetonitrile chemical structure, C9H6N2S2, CAS 351443-25-9
2-(4-(Thiophen-2-yl)thiazol-2-yl)acetonitrile
CAS 351443-25-9C9H6N2S2
2-Chloro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]acetamide chemical structure, C9H7ClN2OS2, CAS 436094-95-0
2-Chloro-N-[4-(thiophen-2-yl)-1,3-thiazol-2-yl]acetamide
CAS 436094-95-0C9H7ClN2OS2
4-(3-Bromothiophen-2-yl)-1,3-thiazol-2-amine chemical structure, C7H5BrN2S2, CAS 81216-90-2
4-(3-Bromothiophen-2-yl)-1,3-thiazol-2-amine
CAS 81216-90-2C7H5BrN2S2
4-(3-Chloro-2-thienyl)-1,3-thiazol-2-amine chemical structure, C7H5ClN2S2, CAS 339114-12-4
4-(3-Chloro-2-thienyl)-1,3-thiazol-2-amine
CAS 339114-12-4C7H5ClN2S2