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Murcko scaffold

3-Phenylbenzofuro[3,2-d]pyrimidine-2,4(1H,3H)-dione scaffold

34 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
34
With full pages
2
Scaffold SMILES

O=c1[nH]c2c(oc3ccccc32)c(=O)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylbenzofuro[3,2-d]pyrimidine-2,4(1H,3H)-dione page
Murcko scaffold O=c1[nH]c2c(oc3ccccc32)c(=O)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

8-Chloro-3-phenyl-1H-[1]benzofuro[3,2-d]pyrimidine-2,4-dione chemical structure, C16H9ClN2O3, CAS 892284-07-0
8-Chloro-3-phenyl-1H-[1]benzofuro[3,2-d]pyrimidine-2,4-dione
CAS 892284-07-0C16H9ClN2O3
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetamide chemical structure, C18H13N3O4, CAS 877656-68-3
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetamide
CAS 877656-68-3C18H13N3O4
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N,N-diethylacetamide chemical structure, C22H21N3O4, CAS 877656-84-3
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N,N-diethylacetamide
CAS 877656-84-3C22H21N3O4
Ethyl 2-(2,4-dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetate chemical structure, C20H16N2O5, CAS 877656-86-5
Ethyl 2-(2,4-dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetate
CAS 877656-86-5C20H16N2O5
2-[3-(4-Methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C19H15N3O4, CAS 877656-92-3
2-[3-(4-Methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877656-92-3C19H15N3O4
N,N-Diethyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C23H23N3O4, CAS 877657-34-6
N,N-Diethyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877657-34-6C23H23N3O4
Methyl 2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate chemical structure, C20H16N2O5, CAS 895789-14-7
Methyl 2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate
CAS 895789-14-7C20H16N2O5
Ethyl 2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate chemical structure, C21H18N2O5, CAS 877657-36-8
Ethyl 2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate
CAS 877657-36-8C21H18N2O5
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C18H12FN3O4, CAS 895789-53-4
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 895789-53-4C18H12FN3O4
N,N-Diethyl-2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C22H20FN3O4, CAS 877657-55-1
N,N-Diethyl-2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877657-55-1C22H20FN3O4
Methyl 2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate chemical structure, C19H13FN2O5, CAS 877657-57-3
Methyl 2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate
CAS 877657-57-3C19H13FN2O5
Ethyl 2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate chemical structure, C20H15FN2O5, CAS 877657-59-5
Ethyl 2-[3-(4-fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetate
CAS 877657-59-5C20H15FN2O5
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-methylacetamide chemical structure, C19H15N3O4, CAS 877657-61-9
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-methylacetamide
CAS 877657-61-9C19H15N3O4
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-propan-2-ylacetamide chemical structure, C21H19N3O4, CAS 877657-63-1
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-propan-2-ylacetamide
CAS 877657-63-1C21H19N3O4
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-(2-methoxyethyl)acetamide chemical structure, C21H19N3O5, CAS 877657-65-3
2-(2,4-Dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)-N-(2-methoxyethyl)acetamide
CAS 877657-65-3C21H19N3O5
N-tert-Butyl-2-(2,4-dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetamide chemical structure, C22H21N3O4, CAS 877657-67-5
N-tert-Butyl-2-(2,4-dioxo-3-phenyl-[1]benzofuro[3,2-d]pyrimidin-1-yl)acetamide
CAS 877657-67-5C22H21N3O4
2-(2,4-Dioxo-3-phenyl-3,4-dihydrobenzofuro[3,2-d]pyrimidin-1(2H)-yl)-N,N-diisopropylacetamide chemical structure, C24H25N3O4, CAS 877657-69-7
2-(2,4-Dioxo-3-phenyl-3,4-dihydrobenzofuro[3,2-d]pyrimidin-1(2H)-yl)-N,N-diisopropylacetamide
CAS 877657-69-7C24H25N3O4
N-Methyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C20H17N3O4, CAS 877657-73-3
N-Methyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877657-73-3C20H17N3O4
2-(2,4-Dioxo-3-(p-tolyl)-3,4-dihydrobenzofuro[3,2-d]pyrimidin-1(2H)-yl)-N-isopropylacetamide chemical structure, C22H21N3O4, CAS 877657-74-4
2-(2,4-Dioxo-3-(p-tolyl)-3,4-dihydrobenzofuro[3,2-d]pyrimidin-1(2H)-yl)-N-isopropylacetamide
CAS 877657-74-4C22H21N3O4
N-(2-Methoxyethyl)-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C22H21N3O5, CAS 877657-75-5
N-(2-Methoxyethyl)-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877657-75-5C22H21N3O5
N-tert-Butyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide chemical structure, C23H23N3O4, CAS 877657-76-6
N-tert-Butyl-2-[3-(4-methylphenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]acetamide
CAS 877657-76-6C23H23N3O4
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-methylacetamide chemical structure, C19H14FN3O4, CAS 895791-98-7
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-methylacetamide
CAS 895791-98-7C19H14FN3O4
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-propan-2-ylacetamide chemical structure, C21H18FN3O4, CAS 895792-12-8
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-propan-2-ylacetamide
CAS 895792-12-8C21H18FN3O4
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-(2-methoxyethyl)acetamide chemical structure, C21H18FN3O5, CAS 887456-02-2
2-[3-(4-Fluorophenyl)-2,4-dioxo-[1]benzofuro[3,2-d]pyrimidin-1-yl]-N-(2-methoxyethyl)acetamide
CAS 887456-02-2C21H18FN3O5