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Murcko scaffold

Ring system with 4 rings and 19 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
12
With full pages
2
Scaffold SMILES

c1ccc(-c2ccn3c(c2)nc2ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccn3c(c2)nc2ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1-Amino-3-(2-chlorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C19H10ClN5, CAS 318259-50-6
1-Amino-3-(2-chlorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 318259-50-6C19H10ClN5
1-Amino-3-(2-fluorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C19H10FN5, CAS 300718-99-4
1-Amino-3-(2-fluorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 300718-99-4C19H10FN5
13-Amino-11-(4-methylphenyl)-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,8,10,12-hexaene-10,12-dicarbonitrile chemical structure, C20H13N5, CAS 150651-39-1
13-Amino-11-(4-methylphenyl)-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,8,10,12-hexaene-10,12-dicarbonitrile
CAS 150651-39-1C20H13N5
1-Amino-3-(3-hydroxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C19H11N5O, CAS 333434-21-2
1-Amino-3-(3-hydroxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 333434-21-2C19H11N5O
1-Amino-3-(4-methoxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C20H13N5O, CAS 150651-38-0
1-Amino-3-(4-methoxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 150651-38-0C20H13N5O
1-Amino-3-(4-chlorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C19H10ClN5, CAS 150651-40-4
1-Amino-3-(4-chlorophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 150651-40-4C19H10ClN5
1-Amino-3-(4-fluorophenyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile chemical structure, C19H10FN5, CAS 300719-01-1
1-Amino-3-(4-fluorophenyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile
CAS 300719-01-1C19H10FN5
1-Amino-3-(3-bromophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C19H10BrN5, CAS 312287-07-3
1-Amino-3-(3-bromophenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 312287-07-3C19H10BrN5
1-Amino-3-(3-ethoxy-4-methoxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C22H17N5O2, CAS 312287-08-4
1-Amino-3-(3-ethoxy-4-methoxyphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 312287-08-4C22H17N5O2
1-Amino-3-[4-(3-cyanopropoxy)-3-methoxyphenyl]pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile chemical structure, C24H18N6O2, CAS 442872-61-9
1-Amino-3-[4-(3-cyanopropoxy)-3-methoxyphenyl]pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
CAS 442872-61-9C24H18N6O2
1-Amino-3-(4-(tert-butyl)phenyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile chemical structure, C23H19N5, CAS 885458-42-4
1-Amino-3-(4-(tert-butyl)phenyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile
CAS 885458-42-4C23H19N5
3-(4-(1-Amino-2,4-dicyanobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenyl)propanoic acid chemical structure, C22H15N5O2, CAS 1314881-75-8
3-(4-(1-Amino-2,4-dicyanobenzo[4,5]imidazo[1,2-a]pyridin-3-yl)phenyl)propanoic acid
CAS 1314881-75-8C22H15N5O2