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Murcko scaffold

Ring system with 4 rings and 20 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
13
With full pages
5
Scaffold SMILES

O=c1c2sc3ncccc3c2ncn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2sc3ncccc3c2ncn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

9-(Dimethylamino)-3-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C17H14N4OS, CAS 159583-13-8
9-(Dimethylamino)-3-phenylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 159583-13-8C17H14N4OS
9-(Dimethylamino)-3-(4-methylphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C18H16N4OS, CAS 6048-64-2
9-(Dimethylamino)-3-(4-methylphenyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 6048-64-2C18H16N4OS
12-Nitro-5-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,10,12-pentaen-6-one chemical structure, C15H8N4O3S, CAS 293735-80-5
12-Nitro-5-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,10,12-pentaen-6-one
CAS 293735-80-5C15H8N4O3S
9-Dimethylamino-3-(p-chlorophenyl)-3H-5-thia-1,3,6-triazafluoren-4-one chemical structure, C17H13ClN4OS, CAS 159583-14-9
9-Dimethylamino-3-(p-chlorophenyl)-3H-5-thia-1,3,6-triazafluoren-4-one
CAS 159583-14-9C17H13ClN4OS
9-(Dimethylamino)-3-(4-methoxyphenyl)-4-pyrido[1,2]thieno[3,4-d]pyrimidinone chemical structure, C18H16N4O2S, CAS 159583-16-1
9-(Dimethylamino)-3-(4-methoxyphenyl)-4-pyrido[1,2]thieno[3,4-d]pyrimidinone
CAS 159583-16-1C18H16N4O2S
7,9-Dimethyl-3-[3-(trifluoromethyl)phenyl]pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C18H12F3N3OS, CAS 371213-81-9
7,9-Dimethyl-3-[3-(trifluoromethyl)phenyl]pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 371213-81-9C18H12F3N3OS
7-(Difluoromethyl)-3-(2,4-dimethylphenyl)-9-methylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C19H15F2N3OS, CAS 677014-65-2
7-(Difluoromethyl)-3-(2,4-dimethylphenyl)-9-methylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 677014-65-2C19H15F2N3OS
3-(2,4-Dichlorophenyl)-7-(difluoromethyl)-9-methylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C17H9Cl2F2N3OS, CAS 677329-74-7
3-(2,4-Dichlorophenyl)-7-(difluoromethyl)-9-methylpyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4(3H)-one
CAS 677329-74-7C17H9Cl2F2N3OS
13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one chemical structure, C19H18N4OS, CAS 869802-44-8
13-(Dimethylamino)-5-(4-ethylphenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one
CAS 869802-44-8C19H18N4OS
5-(4-Methoxyphenyl)-13-((prop-2-yn-1-yl)amino)-8-thia-3,5,10-triazatricyclo(7.4.0.0^(2,7))trideca-1(13),2(7),3,9,11-pentaen-6-one chemical structure, C19H14N4O2S, CAS 902747-98-2
5-(4-Methoxyphenyl)-13-((prop-2-yn-1-yl)amino)-8-thia-3,5,10-triazatricyclo(7.4.0.0^(2,7))trideca-1(13),2(7),3,9,11-pentaen-6-one
CAS 902747-98-2C19H14N4O2S
3-(4-Chlorophenyl)-9-(2-propyn-1-ylamino)pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one chemical structure, C18H11ClN4OS, CAS 902747-93-7
3-(4-Chlorophenyl)-9-(2-propyn-1-ylamino)pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one
CAS 902747-93-7C18H11ClN4OS
Pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one, 3-(4-methoxyphenyl)-2,7,9-trimethyl- chemical structure, C19H17N3O2S, CAS 89481-29-8
Pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one, 3-(4-methoxyphenyl)-2,7,9-trimethyl-
CAS 89481-29-8C19H17N3O2S
Pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one, 3-(2-methyl-4-nitrophenyl)-2,7,9-trimethyl- chemical structure, C19H16N4O3S, CAS 89481-30-1
Pyrido(3',2':4,5)thieno(3,2-d)pyrimidin-4(3H)-one, 3-(2-methyl-4-nitrophenyl)-2,7,9-trimethyl-
CAS 89481-30-1C19H16N4O3S