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Murcko scaffold

5,6,7,8-Tetrahydro-2-phenyl(1)benzothieno(2,3-d)pyrimidin-4(1H)-one scaffold

30 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 20
Chemicals: 30
With full pages: 5

Scaffold SMILES

O=c1[nH]c(-c2ccccc2)nc2sc3c(c12)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5,6,7,8-Tetrahydro-2-phenyl(1)benzothieno(2,3-d)pyrimidin-4(1H)-one page

Murcko scaffold O=c1[nH]c(-c2ccccc2)nc2sc3c(c12)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

5,6,7,8-Tetrahydro-2-phenyl(1)benzothieno(2,3-d)pyrimidin-4(1H)-one chemical structure, C16H14N2OS, CAS 19819-18-2

5,6,7,8-Tetrahydro-2-phenyl(1)benzothieno(2,3-d)pyrimidin-4(1H)-one

CAS 19819-18-2C₁₆H₁₄N₂OS

2-(4-Chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C16H13ClN2OS, CAS 60442-58-2

2-(4-Chlorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 60442-58-2C₁₆H₁₃ClN₂OS

2-(2-Hydroxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one chemical structure, C16H14N2O2S, CAS 142354-83-4

2-(2-Hydroxyphenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(1H)-one

CAS 142354-83-4C₁₆H₁₄N₂O₂S

5-(3-Hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one chemical structure, C16H14N2O2S, CAS 357618-26-9

5-(3-Hydroxyphenyl)-8-thia-4,6-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),5-trien-3-one

CAS 357618-26-9C₁₆H₁₄N₂O₂S

2-(2-Chlorophenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C16H13ClN2OS, CAS 300696-98-4

2-(2-Chlorophenyl)-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one

CAS 300696-98-4C₁₆H₁₃ClN₂OS

2-(4-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ol chemical structure, C16H14N2O2S, CAS 142354-84-5

2-(4-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ol

CAS 142354-84-5C₁₆H₁₄N₂O₂S

2-(4-Fluorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C16H13FN2OS, CAS 335215-50-4

2-(4-Fluorophenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 335215-50-4C₁₆H₁₃FN₂OS

2-(4-Methyl-3-nitrophenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C17H15N3O3S, CAS 5950-43-6

2-(4-Methyl-3-nitrophenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one

CAS 5950-43-6C₁₇H₁₅N₃O₃S

2-(4-Methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C17H16N2O2S, CAS 60442-59-3

2-(4-Methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 60442-59-3C₁₇H₁₆N₂O₂S

2-{3-Nitrophenyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ol chemical structure, C16H13N3O3S, CAS 142354-85-6

2-{3-Nitrophenyl}-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-ol

CAS 142354-85-6C₁₆H₁₃N₃O₃S

2-(4-Propan-2-yloxyphenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one chemical structure, C19H20N2O2S, CAS 5953-61-7

2-(4-Propan-2-yloxyphenyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one

CAS 5953-61-7C₁₉H₂₀N₂O₂S

2-(2-Hydroxy-3-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C17H16N2O3S, CAS 357618-27-0

2-(2-Hydroxy-3-methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 357618-27-0C₁₇H₁₆N₂O₃S

2-(2-Methylphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C17H16N2OS, CAS 60557-06-4

2-(2-Methylphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 60557-06-4C₁₇H₁₆N₂OS

[4-(4-Oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)phenoxy]acetic acid chemical structure, C18H16N2O4S, CAS 5948-70-9

[4-(4-Oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)phenoxy]acetic acid

CAS 5948-70-9C₁₈H₁₆N₂O₄S

2-(2-Methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C17H16N2O2S, CAS 142354-86-7

2-(2-Methoxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 142354-86-7C₁₇H₁₆N₂O₂S

2-[4-(Propan-2-yl)phenyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C19H20N2OS, CAS 5952-69-2

2-[4-(Propan-2-yl)phenyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 5952-69-2C₁₉H₂₀N₂OS

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-6-methyl-2-phenyl- chemical structure, C17H16N2OS, CAS 70733-11-8

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-6-methyl-2-phenyl-

CAS 70733-11-8C₁₇H₁₆N₂OS

Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-(3-(trifluoromethyl)phenyl)- chemical structure, C17H13F3N2OS, CAS 120354-29-2

Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-(3-(trifluoromethyl)phenyl)-

CAS 120354-29-2C₁₇H₁₃F₃N₂OS

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-5-methyl-2-(3-(trifluoromethyl)phenyl)- chemical structure, C18H15F3N2OS, CAS 120354-30-5

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-5-methyl-2-(3-(trifluoromethyl)phenyl)-

CAS 120354-30-5C₁₈H₁₅F₃N₂OS

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-6-methyl-2-(3-(trifluoromethyl)phenyl)- chemical structure, C18H15F3N2OS, CAS 120354-31-6

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-6-methyl-2-(3-(trifluoromethyl)phenyl)-

CAS 120354-31-6C₁₈H₁₅F₃N₂OS

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-7-methyl-2-(3-(trifluoromethyl)phenyl)- chemical structure, C18H15F3N2OS, CAS 120354-32-7

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-7-methyl-2-(3-(trifluoromethyl)phenyl)-

CAS 120354-32-7C₁₈H₁₅F₃N₂OS

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-7-methyl-2-phenyl- chemical structure, C17H16N2OS, CAS 95211-45-3

(1)Benzothieno(2,3-d)pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-7-methyl-2-phenyl-

CAS 95211-45-3C₁₇H₁₆N₂OS

4-(7-Ethyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)benzoic acid chemical structure, C19H18N2O3S, CAS 743439-05-6

4-(7-Ethyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)benzoic acid

CAS 743439-05-6C₁₉H₁₈N₂O₃S

2-[3-Bromo-5-methoxy-4-(propan-2-yloxy)phenyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one chemical structure, C20H21BrN2O3S, CAS 872546-06-0

2-[3-Bromo-5-methoxy-4-(propan-2-yloxy)phenyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one

CAS 872546-06-0C₂₀H₂₁BrN₂O₃S