Murcko scaffold
N-(1,3-Benzothiazol-2-yl)-4-piperidin-1-ylsulfonylbenzamide scaffold
329 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 329
- With full pages
- 5
Scaffold SMILES
O=C(Nc1nc2ccccc2s1)c1ccc(S(=O)(=O)N2CCCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 193 to 240 of 329 chemicals
![N-(6-Acetamidobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C23H26N4O4S2, CAS 361479-35-8](/s/IXEYZMYPWVJJRT-UHFFFAOYSA-N.svg)
N-(6-Acetamidobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide
CAS 361479-35-8C23H26N4O4S2
![(Z)-Methyl 2-(6-fluoro-2-((4-((3-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C23H24FN3O5S2, CAS 897734-19-9](/s/KOBDGGGUAXAESG-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(6-fluoro-2-((4-((3-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate
CAS 897734-19-9C23H24FN3O5S2
![(Z)-4-((3-Methylpiperidin-1-yl)sulfonyl)-N-(3-(prop-2-yn-1-yl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H24N4O5S3, CAS 865182-37-2](/s/VBNYAPKXNBYYNX-UHFFFAOYSA-N.svg)
(Z)-4-((3-Methylpiperidin-1-yl)sulfonyl)-N-(3-(prop-2-yn-1-yl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 865182-37-2C23H24N4O5S3
![(Z)-N-(6-Ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C24H29N3O4S2, CAS 850909-93-2](/s/JPDOPJARHJJUNU-UHFFFAOYSA-N.svg)
(Z)-N-(6-Ethoxy-3-ethylbenzo[d]thiazol-2(3H)-ylidene)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 850909-93-2C24H29N3O4S2
N-(3-Ethyl-1,3-benzothiazol-2-ylidene)-4-(3-methylpiperidin-1-yl)sulfonylbenzamide
CAS 850910-81-5C22H25N3O3S2
![(E)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C23H26FN3O3S2, CAS 850910-27-9](/s/KREKZNZLFRKDJZ-UHFFFAOYSA-N.svg)
(E)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 850910-27-9C23H26FN3O3S2
![(Z)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-(2-methoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide chemical structure, C24H30N4O6S3, CAS 865160-18-5](/s/NDGRMDVSTWUVCQ-UHFFFAOYSA-N.svg)
(Z)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-(2-methoxyethyl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide
CAS 865160-18-5C24H30N4O6S3
![(Z)-N-(3-(2-Ethoxyethyl)-6-fluorobenzo[d]thiazol-2(3H)-ylidene)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C24H28FN3O4S2, CAS 897616-36-3](/s/LFTWTZWOGRCAJZ-UHFFFAOYSA-N.svg)
(Z)-N-(3-(2-Ethoxyethyl)-6-fluorobenzo[d]thiazol-2(3H)-ylidene)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 897616-36-3C24H28FN3O4S2
![(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H22FN3O3S2, CAS 683770-36-7](/s/BEJPIPXWCKKNEN-UHFFFAOYSA-N.svg)
(E)-N-(6-Fluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 683770-36-7C21H22FN3O3S2
![(E)-N-(3-Ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C22H24FN3O3S2, CAS 850910-35-9](/s/JNEPOXSIDWASOU-UHFFFAOYSA-N.svg)
(E)-N-(3-Ethyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 850910-35-9C22H24FN3O3S2
![N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H21Cl2N3O3S2, CAS 851080-33-6](/s/OCBHGZLQIXPLPT-UHFFFAOYSA-N.svg)
N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide
CAS 851080-33-6C21H21Cl2N3O3S2
![(Z)-Methyl 2-(6-methoxy-2-((4-(piperidin-1-ylsulfonyl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C23H25N3O6S2, CAS 865199-74-2](/s/RVZCZPBEFGDDIO-UHFFFAOYSA-N.svg)
(Z)-Methyl 2-(6-methoxy-2-((4-(piperidin-1-ylsulfonyl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate
CAS 865199-74-2C23H25N3O6S2
![(E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C22H25N3O4S2, CAS 685106-40-5](/s/NJZSUVNHSOYOAW-UHFFFAOYSA-N.svg)
(E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 685106-40-5C22H25N3O4S2
![N-(6-Bromobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H22BrN3O3S2, CAS 361167-25-1](/s/XOCUBNVRBDIYOU-UHFFFAOYSA-N.svg)
N-(6-Bromobenzo[d]thiazol-2-yl)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide
CAS 361167-25-1C21H22BrN3O3S2
![4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(6-methylbenzo[d]thiazol-2-yl)benzamide chemical structure, C22H25N3O3S2, CAS 361167-26-2](/s/PKBRYPVALZKAEQ-UHFFFAOYSA-N.svg)
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(6-methylbenzo[d]thiazol-2-yl)benzamide
CAS 361167-26-2C22H25N3O3S2
![(Z)-N-(3-Methyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-4-(piperidin-1-ylsulfonyl)benzamide chemical structure, C21H23N3O5S3, CAS 683237-68-5](/s/OLCRVMRMENMTTI-UHFFFAOYSA-N.svg)
(Z)-N-(3-Methyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-4-(piperidin-1-ylsulfonyl)benzamide
CAS 683237-68-5C21H23N3O5S3
![N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide chemical structure, C19H17Cl2N3O3S2, CAS 905678-42-4](/s/WGICCYPBGCPQES-UHFFFAOYSA-N.svg)
N-(4,5-Dichlorobenzo[d]thiazol-2-yl)-4-(piperidin-1-ylsulfonyl)benzamide
CAS 905678-42-4C19H17Cl2N3O3S2
![(Z)-N-(6-Methoxy-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C24H29N3O5S2, CAS 1006265-89-9](/s/LWEZOAHCLHQPPG-UHFFFAOYSA-N.svg)
(Z)-N-(6-Methoxy-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 1006265-89-9C24H29N3O5S2
![4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(4-methylbenzo[d]thiazol-2-yl)benzamide chemical structure, C22H25N3O3S2, CAS 361167-29-5](/s/VCGVIXANMATSLQ-UHFFFAOYSA-N.svg)
4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
CAS 361167-29-5C22H25N3O3S2
![(Z)-Ethyl 2-(2-((4-((2-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate chemical structure, C24H28N4O7S3, CAS 865248-08-4](/s/AZCHHCWMJIXHKJ-UHFFFAOYSA-N.svg)
(Z)-Ethyl 2-(2-((4-((2-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate
CAS 865248-08-4C24H28N4O7S3
![N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H22ClN3O3S2, CAS 896675-95-9](/s/QAABSSBAMILVEQ-UHFFFAOYSA-N.svg)
N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 896675-95-9C21H22ClN3O3S2
![N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H22ClN3O3S2, CAS 896675-97-1](/s/XTOWLMLHDMFODF-UHFFFAOYSA-N.svg)
N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 896675-97-1C21H22ClN3O3S2
![N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide chemical structure, C21H22ClN3O3S2, CAS 896675-99-3](/s/BNTJRNBKGVOGQX-UHFFFAOYSA-N.svg)
N-(7-Chloro-4-methylbenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide
CAS 896675-99-3C21H22ClN3O3S2
N-(3-Ethyl-6-methyl-1,3-benzothiazol-2-ylidene)-4-(3-methylpiperidin-1-yl)sulfonylbenzamide
CAS 850909-08-9C23H27N3O3S2
- (E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide685106-36-9C22H25N3O4S2
- (E)-N-(4-Methoxy-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide685106-38-1C22H25N3O4S2
- N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide683260-06-2C21H22N4O6S2
- N-[3-(2-Ethoxyethyl)-1,3-benzothiazol-2-ylidene]-4-(3-methylpiperidin-1-yl)sulfonylbenzamide865162-46-5C24H29N3O4S2
- (Z)-N-(3-Ethyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide1007540-99-9C22H24FN3O3S2
- (Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide865176-37-0C24H28N4O5S3
- (Z)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-ethyl-4-methoxybenzo[d]thiazol-2(3H)-ylidene)benzamide533868-54-1C24H29N3O4S2
- (Z)-N-(6-Chloro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamide393835-18-2C22H24ClN3O3S2
- N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-4-((3-methylpiperidin-1-yl)sulfonyl)benzamide896676-40-7C22H25N3O5S2
- N-(4,7-Dimethoxybenzo[d]thiazol-2-yl)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide896676-41-8C22H25N3O5S2
- N-(3-Methyl-1,3-benzothiazol-2-ylidene)-4-(2-methylpiperidin-1-yl)sulfonylbenzamide683260-95-9C21H23N3O3S2
- (Z)-Methyl 2-(6-fluoro-2-((4-(piperidin-1-ylsulfonyl)benzoyl)imino)benzo[d]thiazol-3(2H)-yl)acetate865198-03-4C22H22FN3O5S2
- (Z)-4-((2-Ethylpiperidin-1-yl)sulfonyl)-N-(3-methyl-6-nitrobenzo[d]thiazol-2(3H)-ylidene)benzamide850910-49-5C22H24N4O5S2
- N-(6-Bromo-1,3-benzothiazol-2-yl)-4-[(2-methylpiperidin-1-yl)sulfonyl]benzamide683268-82-8C20H20BrN3O3S2
- (Z)-Methyl 3-ethyl-2-((4-((3-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-2,3-dihydrobenzo[d]thiazole-6-carboxylate850909-34-1C24H27N3O5S2
- (Z)-4-((4-Methylpiperidin-1-yl)sulfonyl)-N-(3-(prop-2-yn-1-yl)-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)benzamide865182-35-0C23H24N4O5S3
- N-(3,6-Dimethyl-1,3-benzothiazol-2-ylidene)-4-(4-methylpiperidin-1-yl)sulfonylbenzamide683261-01-0C22H25N3O3S2
- (Z)-Methyl 2-(2-((4-((4-methylpiperidin-1-yl)sulfonyl)benzoyl)imino)-6-sulfamoylbenzo[d]thiazol-3(2H)-yl)acetate865199-07-1C23H26N4O7S3
- (Z)-N-(4,6-Difluoro-3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-ethylpiperidin-1-yl)sulfonyl)benzamide1007463-92-4C22H23F2N3O3S2
- (Z)-4-((3,5-Dimethylpiperidin-1-yl)sulfonyl)-N-(3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)benzamide865162-41-0C25H31N3O4S2
- N-(3-Methyl-1,3-benzothiazol-2-ylidene)-4-(3-methylpiperidin-1-yl)sulfonylbenzamide683260-94-8C21H23N3O3S2
- (Z)-N-(3-(2-Ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-4-((2-methylpiperidin-1-yl)sulfonyl)benzamide865162-47-6C24H29N3O4S2
- 4-(3,5-Dimethylpiperidin-1-yl)sulfonyl-N-(3-prop-2-ynyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)benzamide865182-24-7C24H26N4O5S3
- (Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)-4-((2-ethylpiperidin-1-yl)sulfonyl)benzamide865180-41-2C24H28N4O5S3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1nc2ccccc2s1)c1ccc(S(=O)(=O)N2CCOCC2)cc110 chemicals
O=C(Nc1cc2c(s1)CNCC2)c1ccc(S(=O)(=O)N2CCCCC2)cc19 chemicals
O=C(Nc1cc2c(s1)CNCC2)c1ccc(S(=O)(=O)N2CCOCC2)cc18 chemicals
O=C(Nc1cc2c(s1)CNCC2)c1ccc(C(=O)c2ccccc2)cc16 chemicals
O=C(Nc1nc2ccccc2s1)c1ccc(C(=O)c2ccccc2)cc16 chemicals
O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1cc2ccccc2o13 chemicals
O=C(Nc1nc2ccccc2s1)C1CCN(S(=O)(=O)c2ccccc2)CC11 chemical
O=C(Nc1cc2ccccc2s1)N1CCN(Cc2ccccc2)CC11 chemical
O=C1c2ccccc2C(=O)N1CCC1CCN(Cc2ccccc2)CC11 chemical![Scaffold O=S(=O)(c1ccc(C=Cc2nc3ccccc3[nH]2)cc1)N1CCCCC1](/scaffold/GCMDSFDPHLEEQV-UHFFFAOYSA-N/structure.svg)
O=S(=O)(c1ccc(C=Cc2nc3ccccc3[nH]2)cc1)N1CCCCC11 chemical
O=C(Nc1ccc(CN2CCCCC2)cc1)c1cc2ccccc2s11 chemical
O=C(CN1C(=O)c2ccccc2C1=O)N1CCN(Cc2ccccc2)CC11 chemical