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Murcko scaffold

1-Cyclobutyl-1H-pyrazole scaffold

329 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 329
With full pages: 30

Scaffold SMILES

c1cnn(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Cyclobutyl-1H-pyrazole page

Murcko scaffold c1cnn(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 329 chemicals

(1s,3s)-3-(1H-Pyrazol-1-yl)cyclobutan-1-ol hydrochloride chemical structure, C7H11ClN2O, CAS 2402839-19-2

(1s,3s)-3-(1H-Pyrazol-1-yl)cyclobutan-1-ol hydrochloride

CAS 2402839-19-2C₇H₁₁ClN₂O

rac-((1r,3r)-3-(1H-Pyrazol-1-yl)cyclobutyl)methanamine dihydrochloride chemical structure, C8H15Cl2N3, CAS 2377033-49-1

rac-((1r,3r)-3-(1H-Pyrazol-1-yl)cyclobutyl)methanamine dihydrochloride

CAS 2377033-49-1C₈H₁₅Cl₂N₃

1-[3-(1H-Pyrazol-1-yl)cyclobutyl]methanamine chemical structure, C8H13N3, CAS 2377032-09-0

1-[3-(1H-Pyrazol-1-yl)cyclobutyl]methanamine

CAS 2377032-09-0C₈H₁₃N₃

Methyl 1-cyclobutylpyrazole-4-carboxylate chemical structure, C9H12N2O2, CAS 2108139-85-9

Methyl 1-cyclobutylpyrazole-4-carboxylate

CAS 2108139-85-9C₉H₁₂N₂O₂

N-(3-Hydroxy-2-pyrazol-1-ylcyclobutyl)prop-2-enamide chemical structure, C10H13N3O2, CAS 2411266-27-6

N-(3-Hydroxy-2-pyrazol-1-ylcyclobutyl)prop-2-enamide

CAS 2411266-27-6C₁₀H₁₃N₃O₂

2-Chloro-N-(3-hydroxy-2-pyrazol-1-ylcyclobutyl)acetamide chemical structure, C9H12ClN3O2, CAS 2411253-59-1

2-Chloro-N-(3-hydroxy-2-pyrazol-1-ylcyclobutyl)acetamide

CAS 2411253-59-1C₉H₁₂ClN₃O₂

(2E)-4-(Dimethylamino)-N-[3-hydroxy-2-(1H-pyrazol-1-yl)cyclobutyl]but-2-enamide chemical structure, C13H20N4O2, CAS 2411332-98-2

(2E)-4-(Dimethylamino)-N-[3-hydroxy-2-(1H-pyrazol-1-yl)cyclobutyl]but-2-enamide

CAS 2411332-98-2C₁₃H₂₀N₄O₂

2-Chloro-N-(3-ethoxy-2-pyrazol-1-ylcyclobutyl)propanamide chemical structure, C12H18ClN3O2, CAS 2411292-12-9

2-Chloro-N-(3-ethoxy-2-pyrazol-1-ylcyclobutyl)propanamide

CAS 2411292-12-9C₁₂H₁₈ClN₃O₂

N-(3-Hydroxy-2-pyrazol-1-ylcyclobutyl)but-2-ynamide chemical structure, C11H13N3O2, CAS 2411274-60-5

N-(3-Hydroxy-2-pyrazol-1-ylcyclobutyl)but-2-ynamide

CAS 2411274-60-5C₁₁H₁₃N₃O₂

4-Bromo-1-cyclobutyl-1H-pyrazole-5-carboxylic acid chemical structure, C8H9BrN2O2, CAS 2416243-51-9

4-Bromo-1-cyclobutyl-1H-pyrazole-5-carboxylic acid

CAS 2416243-51-9C₈H₉BrN₂O₂

(1-(3,3-Difluorocyclobutyl)-1H-pyrazol-4-yl)methanamine chemical structure, C8H11F2N3, CAS 2379590-15-3

(1-(3,3-Difluorocyclobutyl)-1H-pyrazol-4-yl)methanamine

CAS 2379590-15-3C₈H₁₁F₂N₃

(1-(4-Iodo-1H-pyrazol-1-yl)cyclobutyl)methanol chemical structure, C8H11IN2O, CAS 2411707-93-0

(1-(4-Iodo-1H-pyrazol-1-yl)cyclobutyl)methanol

CAS 2411707-93-0C₈H₁₁IN₂O

(Trans)-tert-butyl 3-(4-iodo-1H-pyrazol-1-yl)cyclobutanecarboxylate chemical structure, C12H17IN2O2, CAS 2260788-72-3

(Trans)-tert-butyl 3-(4-iodo-1H-pyrazol-1-yl)cyclobutanecarboxylate

CAS 2260788-72-3C₁₂H₁₇IN₂O₂

2-(4-Bromo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol chemical structure, C8H11BrN2O, CAS 2432829-51-9

2-(4-Bromo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol

CAS 2432829-51-9C₈H₁₁BrN₂O

4-Iodo-1-(3-methoxy-3-methylcyclobutyl)-1H-pyrazole chemical structure, C9H13IN2O, CAS 2419130-23-5

4-Iodo-1-(3-methoxy-3-methylcyclobutyl)-1H-pyrazole

CAS 2419130-23-5C₉H₁₃IN₂O

3-(4-Iodo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol chemical structure, C8H11IN2O, CAS 2419130-22-4

3-(4-Iodo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol

CAS 2419130-22-4C₈H₁₁IN₂O

4-Bromo-1-(2,2-dimethoxycyclobutyl)-1H-pyrazole chemical structure, C9H13BrN2O2, CAS 2433768-39-7

4-Bromo-1-(2,2-dimethoxycyclobutyl)-1H-pyrazole

CAS 2433768-39-7C₉H₁₃BrN₂O₂

Rel-(1s,3s)-3-(4-bromo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol chemical structure, C8H11BrN2O, CAS 2432829-49-5

Rel-(1s,3s)-3-(4-bromo-1H-pyrazol-1-yl)-1-methylcyclobutan-1-ol

CAS 2432829-49-5C₈H₁₁BrN₂O

2-(4-Bromo-1H-pyrazol-1-yl)cyclobutan-1-ol chemical structure, C7H9BrN2O, CAS 2167803-28-1

2-(4-Bromo-1H-pyrazol-1-yl)cyclobutan-1-ol

CAS 2167803-28-1C₇H₉BrN₂O

1-Cyclobutyl-3-ethynyl-1H-pyrazole chemical structure, C9H10N2, CAS 2445784-97-2

1-Cyclobutyl-3-ethynyl-1H-pyrazole

CAS 2445784-97-2C₉H₁₀N₂

1-(3,3-Difluorocyclobutyl)-1H-pyrazol-4-amine chemical structure, C7H9F2N3, CAS 2168695-26-7

1-(3,3-Difluorocyclobutyl)-1H-pyrazol-4-amine

CAS 2168695-26-7C₇H₉F₂N₃

4-(1-(1H-Pyrazol-1-yl)cyclobutyl)butanoic acid chemical structure, C11H16N2O2, CAS 2489784-76-9

4-(1-(1H-Pyrazol-1-yl)cyclobutyl)butanoic acid

CAS 2489784-76-9C₁₁H₁₆N₂O₂

(1r,3r)-3-(4-Bromo-1H-pyrazol-1-yl)cyclobutan-1-ol chemical structure, C7H9BrN2O, CAS 2325898-96-0

(1r,3r)-3-(4-Bromo-1H-pyrazol-1-yl)cyclobutan-1-ol

CAS 2325898-96-0C₇H₉BrN₂O

4-Bromo-1-(1-methylcyclobutyl)pyrazole chemical structure, C8H11BrN2, CAS 2413346-18-4

4-Bromo-1-(1-methylcyclobutyl)pyrazole

CAS 2413346-18-4C₈H₁₁BrN₂