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Murcko scaffold

2-(Pyrrolidin-1-yl)pyrazine scaffold

156 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
156
With full pages
4
Scaffold SMILES

c1cnc(N2CCCC2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-1-yl)pyrazine page
Murcko scaffold c1cnc(N2CCCC2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 156 chemicals

Pyrazinecarbothioamide, 6-(1-pyrrolidinyl)- chemical structure, C9H12N4S, CAS 61689-75-6
Pyrazinecarbothioamide, 6-(1-pyrrolidinyl)-
CAS 61689-75-6C9H12N4S
Pyrazinecarbothioamide, N-[(diethylamino)methyl]-6-(1-pyrrolidinyl)- chemical structure, C14H23N5S, CAS 61689-69-8
Pyrazinecarbothioamide, N-[(diethylamino)methyl]-6-(1-pyrrolidinyl)-
CAS 61689-69-8C14H23N5S
Pyrazinecarbothioamide, N-(hydroxymethyl)-6-(1-pyrrolidinyl)- chemical structure, C10H14N4OS, CAS 61689-74-5
Pyrazinecarbothioamide, N-(hydroxymethyl)-6-(1-pyrrolidinyl)-
CAS 61689-74-5C10H14N4OS
3-(Pyrrolidin-1-yl)pyrazine-2-carbonitrile chemical structure, C9H10N4, CAS 67130-88-5
3-(Pyrrolidin-1-yl)pyrazine-2-carbonitrile
CAS 67130-88-5C9H10N4
3-(Pyrrolidin-1-yl)pyrazine-2-carboxylic Acid chemical structure, C9H11N3O2, CAS 342422-98-4
3-(Pyrrolidin-1-yl)pyrazine-2-carboxylic Acid
CAS 342422-98-4C9H11N3O2
3-(1-Pyrrolidinyl)-2-pyrazinecarbothioamide chemical structure, C9H12N4S, CAS 342422-99-5
3-(1-Pyrrolidinyl)-2-pyrazinecarbothioamide
CAS 342422-99-5C9H12N4S
2-Amino-5-bromo-3-pyrrolidin-1-ylpyrazine chemical structure, C8H11BrN4, CAS 893611-72-8
2-Amino-5-bromo-3-pyrrolidin-1-ylpyrazine
CAS 893611-72-8C8H11BrN4
1-(Pyrazin-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 1103848-03-8
1-(Pyrazin-2-yl)pyrrolidine-2-carboxylic acid
CAS 1103848-03-8C9H11N3O2
tert-Butyl N-[1-(6-chloropyrazin-2-yl)pyrrolidin-3-yl]carbamate chemical structure, C13H19ClN4O2, CAS 159603-27-7
tert-Butyl N-[1-(6-chloropyrazin-2-yl)pyrrolidin-3-yl]carbamate
CAS 159603-27-7C13H19ClN4O2
6-(Pyrrolidin-1-yl)pyrazine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 40262-63-3
6-(Pyrrolidin-1-yl)pyrazine-2-carboxylic acid
CAS 40262-63-3C9H11N3O2
5-(Pyrrolidin-1-yl)pyrazin-2-amine chemical structure, C8H12N4, CAS 1034711-12-0
5-(Pyrrolidin-1-yl)pyrazin-2-amine
CAS 1034711-12-0C8H12N4
2-Chloro-6-(pyrrolidin-1-yl)pyrazine chemical structure, C8H10ClN3, CAS 1000339-30-9
2-Chloro-6-(pyrrolidin-1-yl)pyrazine
CAS 1000339-30-9C8H10ClN3
2-Bromo-5-(pyrrolidin-1-yl)pyrazine chemical structure, C8H10BrN3, CAS 1001050-21-0
2-Bromo-5-(pyrrolidin-1-yl)pyrazine
CAS 1001050-21-0C8H10BrN3
3-(Pyrrolidin-1-yl)pyrazin-2-amine chemical structure, C8H12N4, CAS 912773-12-7
3-(Pyrrolidin-1-yl)pyrazin-2-amine
CAS 912773-12-7C8H12N4
5-(Pyrrolidin-1-yl)pyrazine-2-boronic acid chemical structure, C8H12BN3O2, CAS 1310404-24-0
5-(Pyrrolidin-1-yl)pyrazine-2-boronic acid
CAS 1310404-24-0C8H12BN3O2
6-(Pyrrolidin-1-yl)pyrazine-2-boronic acid chemical structure, C8H12BN3O2, CAS 1310383-13-1
6-(Pyrrolidin-1-yl)pyrazine-2-boronic acid
CAS 1310383-13-1C8H12BN3O2
2-Bromo-6-(pyrrolidin-1-yl)pyrazine chemical structure, C8H10BrN3, CAS 1017781-85-9
2-Bromo-6-(pyrrolidin-1-yl)pyrazine
CAS 1017781-85-9C8H10BrN3
1-(5-Bromopyrazin-2-yl)pyrrolidin-3-ol chemical structure, C8H10BrN3O, CAS 959239-16-8
1-(5-Bromopyrazin-2-yl)pyrrolidin-3-ol
CAS 959239-16-8C8H10BrN3O
2-Bromo-6-(3-hydroxypyrrolidin-1-yl)pyrazine chemical structure, C8H10BrN3O, CAS 1159820-92-4
2-Bromo-6-(3-hydroxypyrrolidin-1-yl)pyrazine
CAS 1159820-92-4C8H10BrN3O
5-(Pyrrolidin-1-yl)pyrazine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 1210030-17-3
5-(Pyrrolidin-1-yl)pyrazine-2-carboxylic acid
CAS 1210030-17-3C9H11N3O2
Methyl 5-(pyrrolidin-1-yl)pyrazine-2-carboxylate chemical structure, C10H13N3O2, CAS 944133-94-2
Methyl 5-(pyrrolidin-1-yl)pyrazine-2-carboxylate
CAS 944133-94-2C10H13N3O2
2-Chloro-3-(pyrrolidin-1-yl)pyrazine chemical structure, C8H10ClN3, CAS 1209459-63-1
2-Chloro-3-(pyrrolidin-1-yl)pyrazine
CAS 1209459-63-1C8H10ClN3
1-(6-Chloropyrazin-2-yl)pyrrolidin-3-ol chemical structure, C8H10ClN3O, CAS 959239-43-1
1-(6-Chloropyrazin-2-yl)pyrrolidin-3-ol
CAS 959239-43-1C8H10ClN3O
1-(Pyrazin-2-yl)pyrrolidin-3-ol chemical structure, C8H11N3O, CAS 1261236-01-4
1-(Pyrazin-2-yl)pyrrolidin-3-ol
CAS 1261236-01-4C8H11N3O