Murcko scaffold
Ring system with 4 rings and 22 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 7
- With full pages
- 1
Scaffold SMILES
O=c1c2ccccc2oc2c(CN3CCCCC3)cccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
Mepixanox
CAS 17854-59-0C20H21NO3
Xanthen-9-one, 3-methoxy-4-(piperidinomethyl)-, hydrochloride
CAS 17854-76-1C20H22ClNO3
Xanthen-9-one, 3-chloro-4-piperidinomethyl-
CAS 43159-88-2C19H18ClNO2
Xanthen-9-one, 3-nitro-4-piperidinomethyl-
CAS 43159-93-9C19H18N2O4
Xanthen-9-one, 3-amino-4-piperidinomethyl-
CAS 43159-97-3C19H20N2O2
Xanthen-9-one, 4-piperidinomethyl-, hydrochloride
CAS 29312-75-2C19H20ClNO2
Xanthen-9-one, 3-isopropoxy-4-(piperidinomethyl)-
CAS 58741-69-8C22H25NO3
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1c2ccccc2C(=O)c2c(Nc3ccccc3)cccc2166 chemicals
C(=C1CCCc2cc3ccccc3nc21)c1ccccc128 chemicals
N=c1ccc2c(=O)n3ccccc3nc2n1Cc1cccnc113 chemicals
O=C1c2ccccc2C(=O)c2c(OC3CCCCO3)cccc218 chemicals
N=c1ccc2c(=O)n3ccccc3nc2n1Cc1ccccc17 chemicals
O=C1c2ccccc2C(=O)c2c(NC3CCCCC3)cccc213 chemicals
O=c1ccoc2cc3cccc(OC4CCCCO4)c3cc122 chemicals
c1ccc(Nc2ccnc3cc4ccccc4cc23)cc12 chemicals
N=c1ccc2c(=O)n3ccccc3nc2n1Cc1ccncc12 chemicals
O=c1c2ccccc2oc2cccc(OC3CCCCO3)c122 chemicals
c1ccc(Oc2cccc3c2Oc2ccccc2O3)cc11 chemical
O=C1CCCc2cc3cccc(OC4CCCCO4)c3cc211 chemical