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Murcko scaffold

3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione scaffold

85 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
85
With full pages
10
Scaffold SMILES

O=C1CNC(=O)c2ccccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione page
Murcko scaffold O=C1CNC(=O)c2ccccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 85 chemicals

4-tert-Butyl-7-chloro-1,3-dihydro-1,4-benzodiazepine-2,5-dione chemical structure, C13H15ClN2O2, CAS 167689-85-2
4-tert-Butyl-7-chloro-1,3-dihydro-1,4-benzodiazepine-2,5-dione
CAS 167689-85-2C13H15ClN2O2
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-3,4-dihydro-4-(1-methylethyl)- chemical structure, C12H13ClN2O2, CAS 167689-87-4
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-3,4-dihydro-4-(1-methylethyl)-
CAS 167689-87-4C12H13ClN2O2
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7-methyl- chemical structure, C14H18N2O2, CAS 167689-91-0
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7-methyl-
CAS 167689-91-0C14H18N2O2
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7-methoxy- chemical structure, C14H18N2O3, CAS 167689-92-1
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7-methoxy-
CAS 167689-92-1C14H18N2O3
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-4-(2,2-dimethylpropyl)-3,4-dihydro- chemical structure, C14H17ClN2O2, CAS 167689-93-2
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-4-(2,2-dimethylpropyl)-3,4-dihydro-
CAS 167689-93-2C14H17ClN2O2
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7,9-dimethyl- chemical structure, C15H20N2O2, CAS 167690-03-1
1H-1,4-Benzodiazepine-2,5-dione, 4-(1,1-dimethylethyl)-3,4-dihydro-7,9-dimethyl-
CAS 167690-03-1C15H20N2O2
9-Chloro-11-methyl-5-tert-butyl-2,5-Diazabicyclo(5.4.0)undeca-8,10,12-triene-3,6-dione, 9-chloro-11-methyl-5-tert-butyl- chemical structure, C14H17ClN2O2, CAS 167690-08-6
9-Chloro-11-methyl-5-tert-butyl-2,5-Diazabicyclo(5.4.0)undeca-8,10,12-triene-3,6-dione, 9-chloro-11-methyl-5-tert-butyl-
CAS 167690-08-6C14H17ClN2O2
7-Chloro-3H-1,4-benzodiazepin-2,5(1H,4H)-dione chemical structure, C9H7ClN2O2, CAS 5177-39-9
7-Chloro-3H-1,4-benzodiazepin-2,5(1H,4H)-dione
CAS 5177-39-9C9H7ClN2O2
8-Chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione chemical structure, C10H9ClN2O2, CAS 5973-31-9
8-Chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS 5973-31-9C10H9ClN2O2
7-Chloro-5-hydroxy-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C15H17ClN2O2, CAS 258849-85-3
7-Chloro-5-hydroxy-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-85-3C15H17ClN2O2
3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione chemical structure, C9H8N2O2, CAS 5118-94-5
3,4-Dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS 5118-94-5C9H8N2O2
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-3,4-dihydro-1-methyl- chemical structure, C10H9ClN2O2, CAS 5973-28-4
1H-1,4-Benzodiazepine-2,5-dione, 7-chloro-3,4-dihydro-1-methyl-
CAS 5973-28-4C10H9ClN2O2
4-Methyl-7-nitro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione chemical structure, C10H9N3O4, CAS 84377-96-8
4-Methyl-7-nitro-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS 84377-96-8C10H9N3O4
3,4-Dihydro-7-fluoro-4-methyl-1H-1,4-benzodiazepine-2,5-dione chemical structure, C10H9FN2O2, CAS 78755-80-3
3,4-Dihydro-7-fluoro-4-methyl-1H-1,4-benzodiazepine-2,5-dione
CAS 78755-80-3C10H9FN2O2
(R)-3-(2,5-Dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-3-yl)propanoic acid chemical structure, C12H12N2O4, CAS 1630765-36-4
(R)-3-(2,5-Dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-3-yl)propanoic acid
CAS 1630765-36-4C12H12N2O4
3-[(3S)-2,5-Dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl]propanoic acid chemical structure, C12H12N2O4, CAS 1217809-77-2
3-[(3S)-2,5-Dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl]propanoic acid
CAS 1217809-77-2C12H12N2O4
2,5-Dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-8-carboxylic acid chemical structure, C10H8N2O4, CAS 195985-12-7
2,5-Dioxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-8-carboxylic acid
CAS 195985-12-7C10H8N2O4
7-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione chemical structure, C9H7BrN2O2, CAS 195986-74-4
7-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS 195986-74-4C9H7BrN2O2
7-Amino-3-methyl-3,4-dihydro-1H-benzo(e)(1,4)diazepine-2,5-dione chemical structure, C10H11N3O2, CAS 1009315-86-9
7-Amino-3-methyl-3,4-dihydro-1H-benzo(e)(1,4)diazepine-2,5-dione
CAS 1009315-86-9C10H11N3O2
1-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione chemical structure, C10H10N2O2, CAS 1133-42-2
1-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione
CAS 1133-42-2C10H10N2O2
4-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione chemical structure, C10H10N2O2, CAS 3415-35-8
4-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-2,5-dione
CAS 3415-35-8C10H10N2O2
7-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione chemical structure, C10H10N2O2, CAS 422318-46-5
7-Methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione
CAS 422318-46-5C10H10N2O2
3-Methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione chemical structure, C10H10N2O2, CAS 24919-37-7
3-Methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
CAS 24919-37-7C10H10N2O2
3-(2,5-Dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl)propanoic acid chemical structure, C12H12N2O4, CAS 24919-53-7
3-(2,5-Dioxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-3-yl)propanoic acid
CAS 24919-53-7C12H12N2O4