Murcko scaffold
N-(Phenylcarbamothioyl)pyridine-3-carboxamide scaffold
33 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 33
- With full pages
- 14
Scaffold SMILES
O=C(NC(=S)Nc1ccccc1)c1cccnc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 33 of 33 chemicals
![N-[(4-Acetylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H13N3O2S, CAS 299201-13-1](/s/RRUBDEKKSNDNFC-UHFFFAOYSA-N.svg)
N-[(4-Acetylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 299201-13-1C15H13N3O2S
![N-[(2-Cyanophenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H10N4OS, CAS 332389-66-9](/s/JMJLEBWTWRSAQN-UHFFFAOYSA-N.svg)
N-[(2-Cyanophenyl)carbamothioyl]pyridine-3-carboxamide
CAS 332389-66-9C14H10N4OS
N-(Phenylcarbamothioyl)pyridine-3-carboxamide
CAS 388071-30-5C13H11N3OS
![N-[Ethyl(phenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H15N3OS, CAS 412937-29-2](/s/ARZMXAORQLRAIX-UHFFFAOYSA-N.svg)
N-[Ethyl(phenyl)carbamothioyl]pyridine-3-carboxamide
CAS 412937-29-2C15H15N3OS
![N-[(2-Chlorophenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C13H10ClN3OS, CAS 388071-32-7](/s/FHNAQXUWFQFZLM-UHFFFAOYSA-N.svg)
N-[(2-Chlorophenyl)carbamothioyl]pyridine-3-carboxamide
CAS 388071-32-7C13H10ClN3OS
![N-[(4-Methoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H13N3O2S, CAS 306766-64-3](/s/QLWJSHDGSWFZHT-UHFFFAOYSA-N.svg)
N-[(4-Methoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 306766-64-3C14H13N3O2S
Methyl 4-(pyridine-3-carbonylcarbamothioylamino)benzoate
CAS 306766-66-5C15H13N3O3S
3-(3-Nicotinoylthioureido)benzoic acid
CAS 370574-29-1C14H11N3O3S
Ethyl 3-(pyridine-3-carbonylcarbamothioylamino)benzoate
CAS 400828-85-5C16H15N3O3S
![N-[(2-Methyl-5-nitrophenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12N4O3S, CAS 693236-09-8](/s/RXHLVGGITZONEK-UHFFFAOYSA-N.svg)
N-[(2-Methyl-5-nitrophenyl)carbamothioyl]pyridine-3-carboxamide
CAS 693236-09-8C14H12N4O3S
![5-Bromo-N-[(3-hydroxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C13H10BrN3O2S, CAS 431908-42-8](/s/HIBPDMCVJVYHCC-UHFFFAOYSA-N.svg)
5-Bromo-N-[(3-hydroxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431908-42-8C13H10BrN3O2S
![5-Bromo-N-[(4-methylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12BrN3OS, CAS 431940-07-7](/s/MDOBRZLJZHBYSP-UHFFFAOYSA-N.svg)
5-Bromo-N-[(4-methylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431940-07-7C14H12BrN3OS
![5-Bromo-N-[(3-chloro-4-methylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H11BrClN3OS, CAS 431980-83-5](/s/CHFKAPOPKSZPIH-UHFFFAOYSA-N.svg)
5-Bromo-N-[(3-chloro-4-methylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431980-83-5C14H11BrClN3OS
![5-Bromo-N-[(3-chloro-2-methylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H11BrClN3OS, CAS 432020-74-1](/s/GTRNPYJTPWGGMC-UHFFFAOYSA-N.svg)
5-Bromo-N-[(3-chloro-2-methylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 432020-74-1C14H11BrClN3OS
![5-Bromo-N-[(4-ethoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H14BrN3O2S, CAS 431932-71-7](/s/ITWGBXMOFQSQSI-UHFFFAOYSA-N.svg)
5-Bromo-N-[(4-ethoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431932-71-7C15H14BrN3O2S
![5-Bromo-N-[(4-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12BrN3O2S, CAS 431980-75-5](/s/BMAUCLNWVMBFNK-UHFFFAOYSA-N.svg)
5-Bromo-N-[(4-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431980-75-5C14H12BrN3O2S
![5-Bromo-N-[(2-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12BrN3O2S, CAS 431941-31-0](/s/ZINFACBPSAWDDA-UHFFFAOYSA-N.svg)
5-Bromo-N-[(2-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431941-31-0C14H12BrN3O2S
![5-Bromo-N-[(3-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12BrN3O2S, CAS 431906-63-7](/s/KRFRXGNJRXPBBD-UHFFFAOYSA-N.svg)
5-Bromo-N-[(3-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431906-63-7C14H12BrN3O2S
![5-Bromo-N-[(2,4-dimethylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H14BrN3OS, CAS 431928-61-9](/s/FQXRXXPMHXMASY-UHFFFAOYSA-N.svg)
5-Bromo-N-[(2,4-dimethylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431928-61-9C15H14BrN3OS
![5-Bromo-N-[(2,5-dimethylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H14BrN3OS, CAS 431909-55-6](/s/YKCIHAQWZCDMRG-UHFFFAOYSA-N.svg)
5-Bromo-N-[(2,5-dimethylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 431909-55-6C15H14BrN3OS
![Propan-2-yl 4-[(5-bromopyridine-3-carbonyl)carbamothioylamino]benzoate chemical structure, C17H16BrN3O3S, CAS 445406-03-1](/s/HWIHVLRRZGTMMI-UHFFFAOYSA-N.svg)
Propan-2-yl 4-[(5-bromopyridine-3-carbonyl)carbamothioylamino]benzoate
CAS 445406-03-1C17H16BrN3O3S
![5-Bromo-N-[[2-(trifluoromethyl)phenyl]carbamothioyl]pyridine-3-carboxamide chemical structure, C14H9BrF3N3OS, CAS 430443-74-6](/s/BQAPLDYHNMQWFT-UHFFFAOYSA-N.svg)
5-Bromo-N-[[2-(trifluoromethyl)phenyl]carbamothioyl]pyridine-3-carboxamide
CAS 430443-74-6C14H9BrF3N3OS
![5-Bromo-N-[(2,4-dimethoxyphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C15H14BrN3O3S, CAS 429636-63-5](/s/LJVVPSDJQQKVBU-UHFFFAOYSA-N.svg)
5-Bromo-N-[(2,4-dimethoxyphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 429636-63-5C15H14BrN3O3S
![N-[(2-Bromo-4-methylphenyl)carbamothioyl]pyridine-3-carboxamide chemical structure, C14H12BrN3OS, CAS 496772-49-7](/s/IBHZZNRQYCIQND-UHFFFAOYSA-N.svg)
N-[(2-Bromo-4-methylphenyl)carbamothioyl]pyridine-3-carboxamide
CAS 496772-49-7C14H12BrN3OS
- Butyl 4-[(5-bromopyridine-3-carbonyl)carbamothioylamino]benzoate430443-93-9C18H18BrN3O3S
- 2-Chloro-N-[(4-methoxyphenyl)carbamothioyl]pyridine-3-carboxamide89374-29-8C14H12ClN3O2S
- N-(4-Bromophenyl)-N'-[(2-chloro-3-pyridyl)carbonyl]thiourea89374-30-1C13H9BrClN3OS
- 5-Bromo-N-{[5-(butan-2-yl)-2-hydroxyphenyl]carbamothioyl}pyridine-3-carboxamide433318-02-6C17H18BrN3O2S
- N-[(4-Ethoxy-2-nitrophenyl)carbamothioyl]pyridine-3-carboxamide306766-67-6C15H14N4O4S
- N-[(3-Chloro-2-hydroxy-5-nitrophenyl)carbamothioyl]pyridine-3-carboxamide329713-46-4C13H9ClN4O4S
- Ach-806870142-71-5C19H20F3N3O2S
- 2-Chloro-N-(phenylcarbamothioyl)pyridine-3-carboxamide89374-26-5C13H10ClN3OS
- N-[(2,5-Dichloro-3-pyridyl)carbonyl]-N'-(4-methoxyphenyl)thiourea680216-91-5C14H11Cl2N3O2S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1ccccc1476 chemicals
O=C(NN=Cc1ccccc1)c1ccccc1265 chemicals
O=C(C=Cc1ccccc1)Nc1ccccc1175 chemicals
O=C(CCc1ccccc1)Nc1ccccc1153 chemicals
O=C(NCCc1ccccc1)c1ccccc1147 chemicals
S=C(NCc1ccccc1)Nc1ccccc1127 chemicals
O=C(CCNc1ccccc1)c1ccccc1120 chemicals
O=C(NC(=S)Nc1ccccc1)c1ccccc196 chemicals
O=S(=O)(NCCc1ccccc1)c1ccccc183 chemicals
O=C(CNc1ccccc1)Nc1ccccc183 chemicals
O=C(CSc1ccccc1)Nc1ccccc177 chemicals
c1ccc(CCNCc2ccccc2)cc173 chemicals