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Murcko scaffold

Ring system with 4 rings and 22 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
14
With full pages
5
Scaffold SMILES

O=c1nc2n(-c3ccccc3)c3ccccc3cc-2c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1nc2n(-c3ccccc3)c3ccccc3cc-2c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

3-Butyl-10-(2,3-dimethylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C23H23N3O2, CAS 310421-60-4
3-Butyl-10-(2,3-dimethylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 310421-60-4C23H23N3O2
3-Methyl-10-(4-methylphenyl)pyrimido[4,5-b]quinoline-2,4-dione chemical structure, C19H15N3O2, CAS 76896-48-5
3-Methyl-10-(4-methylphenyl)pyrimido[4,5-b]quinoline-2,4-dione
CAS 76896-48-5C19H15N3O2
10-(4-Methylphenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione chemical structure, C18H12N4O4, CAS 310421-56-8
10-(4-Methylphenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione
CAS 310421-56-8C18H12N4O4
8-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione chemical structure, C17H10ClN3O2, CAS 84459-37-0
8-Chloro-10-phenylpyrimido[4,5-b]quinoline-2,4-dione
CAS 84459-37-0C17H10ClN3O2
3-Methyl-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C18H13N3O2, CAS 69083-37-0
3-Methyl-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 69083-37-0C18H13N3O2
10-(3-Chlorophenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione chemical structure, C17H9ClN4O4, CAS 317326-90-2
10-(3-Chlorophenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione
CAS 317326-90-2C17H9ClN4O4
10-(4-Chlorophenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione chemical structure, C17H9ClN4O4, CAS 317326-91-3
10-(4-Chlorophenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione
CAS 317326-91-3C17H9ClN4O4
3-Butyl-10-(2,4-dimethylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C23H23N3O2, CAS 317326-94-6
3-Butyl-10-(2,4-dimethylphenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 317326-94-6C23H23N3O2
3-Butyl-10-(4-chlorophenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C21H18ClN3O2, CAS 317326-95-7
3-Butyl-10-(4-chlorophenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 317326-95-7C21H18ClN3O2
3-Butyl-10-(4-fluorophenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C21H18FN3O2, CAS 310421-62-6
3-Butyl-10-(4-fluorophenyl)pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 310421-62-6C21H18FN3O2
10-(3-Bromophenyl)-3-butylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C21H18BrN3O2, CAS 354562-86-0
10-(3-Bromophenyl)-3-butylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 354562-86-0C21H18BrN3O2
7-Nitro-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione chemical structure, C17H10N4O4, CAS 84459-36-9
7-Nitro-10-phenylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione
CAS 84459-36-9C17H10N4O4
10-(3-Aminophenyl)-2,4-dioxo-2H,3H,4H,10H-pyrimido[4,5-b]quinoline-8-carbonitrile chemical structure, C18H11N5O2, CAS 1448807-88-2
10-(3-Aminophenyl)-2,4-dioxo-2H,3H,4H,10H-pyrimido[4,5-b]quinoline-8-carbonitrile
CAS 1448807-88-2C18H11N5O2
10-(3-Aminophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile, hydrochloride chemical structure, C18H12ClN5O2, CAS 2490418-78-3
10-(3-Aminophenyl)-2,4-dioxopyrimido[4,5-b]quinoline-8-carbonitrile, hydrochloride
CAS 2490418-78-3C18H12ClN5O2