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Murcko scaffold

Ring system with 2 rings and 17 atoms

66 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 17
Chemicals: 66
With full pages: 26

Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1ccccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccccc1)Nc1ccccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

2-Propenamide, 3-phenyl-N-2-pyridinyl-, monohydrochloride chemical structure, C14H13ClN2O, CAS 63731-90-8

2-Propenamide, 3-phenyl-N-2-pyridinyl-, monohydrochloride

CAS 63731-90-8C₁₄H₁₃ClN₂O

2-Propenamide, 3-(4-methoxyphenyl)-N-2-pyridinyl-, (E)- chemical structure, C15H14N2O2, CAS 113985-25-4

2-Propenamide, 3-(4-methoxyphenyl)-N-2-pyridinyl-, (E)-

CAS 113985-25-4C₁₅H₁₄N₂O₂

3-(4-Fluorophenyl)-N-(2-pyridinyl)acrylamide chemical structure, C14H11FN2O, CAS 340258-31-3

3-(4-Fluorophenyl)-N-(2-pyridinyl)acrylamide

CAS 340258-31-3C₁₄H₁₁FN₂O

N-(5-Chloro-2-pyridinyl)-3-phenylacrylamide chemical structure, C14H11ClN2O, CAS 100622-76-2

N-(5-Chloro-2-pyridinyl)-3-phenylacrylamide

CAS 100622-76-2C₁₄H₁₁ClN₂O

(2E)-2-Cyano-3-(4-methylphenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide chemical structure, C17H15N3O, CAS 488825-85-0

(2E)-2-Cyano-3-(4-methylphenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide

CAS 488825-85-0C₁₇H₁₅N₃O

(E)-N-(5-Chloropyridin-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide chemical structure, C17H17ClN2O4, CAS 469878-57-7

(E)-N-(5-Chloropyridin-2-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-enamide

CAS 469878-57-7C₁₇H₁₇ClN₂O₄

(E)-3-(2,6-Dichlorophenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide chemical structure, C15H12Cl2N2O, CAS 560097-21-4

(E)-3-(2,6-Dichlorophenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide

CAS 560097-21-4C₁₅H₁₂Cl₂N₂O

(E)-3-(2,4-Dichlorophenyl)-N-(4,6-dimethylpyridin-2-yl)prop-2-enamide chemical structure, C16H14Cl2N2O, CAS 1164536-90-6

(E)-3-(2,4-Dichlorophenyl)-N-(4,6-dimethylpyridin-2-yl)prop-2-enamide

CAS 1164536-90-6C₁₆H₁₄Cl₂N₂O

(E)-N-(4,6-Dimethylpyridin-2-yl)-3-(4-nitrophenyl)prop-2-enamide chemical structure, C16H15N3O3, CAS 418786-77-3

(E)-N-(4,6-Dimethylpyridin-2-yl)-3-(4-nitrophenyl)prop-2-enamide

CAS 418786-77-3C₁₆H₁₅N₃O₃

(E)-3-(4-tert-Butylphenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide chemical structure, C19H22N2O, CAS 424809-05-2

(E)-3-(4-tert-Butylphenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide

CAS 424809-05-2C₁₉H₂₂N₂O

(E)-3-(4-Chlorophenyl)-N-(5-chloropyridin-2-yl)prop-2-enamide chemical structure, C14H10Cl2N2O, CAS 425421-78-9

(E)-3-(4-Chlorophenyl)-N-(5-chloropyridin-2-yl)prop-2-enamide

CAS 425421-78-9C₁₄H₁₀Cl₂N₂O

3-(2-Chlorophenyl)-N-(5-chloro-2-pyridinyl)acrylamide chemical structure, C14H10Cl2N2O, CAS 6187-44-6

3-(2-Chlorophenyl)-N-(5-chloro-2-pyridinyl)acrylamide

CAS 6187-44-6C₁₄H₁₀Cl₂N₂O

(2E)-N-(5-Chloropyridin-2-yl)-3-(3-nitrophenyl)prop-2-enamide chemical structure, C14H10ClN3O3, CAS 6235-05-8

(2E)-N-(5-Chloropyridin-2-yl)-3-(3-nitrophenyl)prop-2-enamide

CAS 6235-05-8C₁₄H₁₀ClN₃O₃

(E)-N-(5-Chloropyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide chemical structure, C14H10ClN3O3, CAS 600122-68-7

(E)-N-(5-Chloropyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide

CAS 600122-68-7C₁₄H₁₀ClN₃O₃

(E)-N-(4-Methylpyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide chemical structure, C15H13N3O3, CAS 1429221-56-6

(E)-N-(4-Methylpyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide

CAS 1429221-56-6C₁₅H₁₃N₃O₃

(E)-N-(5-Chloropyridin-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-enamide chemical structure, C16H15ClN2O3, CAS 377757-42-1

(E)-N-(5-Chloropyridin-2-yl)-3-(3,4-dimethoxyphenyl)prop-2-enamide

CAS 377757-42-1C₁₆H₁₅ClN₂O₃

(E)-N-(6-Methylpyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide chemical structure, C15H13N3O3, CAS 339218-37-0

(E)-N-(6-Methylpyridin-2-yl)-3-(2-nitrophenyl)prop-2-enamide

CAS 339218-37-0C₁₅H₁₃N₃O₃

(E)-3-(2,6-Dichlorophenyl)-N-(3-methylpyridin-2-yl)prop-2-enamide chemical structure, C15H12Cl2N2O, CAS 544425-33-4

(E)-3-(2,6-Dichlorophenyl)-N-(3-methylpyridin-2-yl)prop-2-enamide

CAS 544425-33-4C₁₅H₁₂Cl₂N₂O

(E)-3-(2-Chloro-6-fluorophenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide chemical structure, C15H12ClFN2O, CAS 543719-11-5

(E)-3-(2-Chloro-6-fluorophenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide

CAS 543719-11-5C₁₅H₁₂ClFN₂O

(E)-2-Cyano-3-(2-hydroxyphenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide chemical structure, C16H13N3O2, CAS 488708-01-6

(E)-2-Cyano-3-(2-hydroxyphenyl)-N-(6-methylpyridin-2-yl)prop-2-enamide

CAS 488708-01-6C₁₆H₁₃N₃O₂

(2E)-2-Cyano-3-phenyl-N-(pyridin-2-yl)prop-2-enamide chemical structure, C15H11N3O, CAS 1006694-43-4

(2E)-2-Cyano-3-phenyl-N-(pyridin-2-yl)prop-2-enamide

CAS 1006694-43-4C₁₅H₁₁N₃O

(E)-2-Cyano-3-(2-hydroxyphenyl)-N-pyridin-2-ylprop-2-enamide chemical structure, C15H11N3O2, CAS 489443-51-8

(E)-2-Cyano-3-(2-hydroxyphenyl)-N-pyridin-2-ylprop-2-enamide

CAS 489443-51-8C₁₅H₁₁N₃O₂

(2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide chemical structure, C16H13N3O2, CAS 367278-79-3

(2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide

CAS 367278-79-3C₁₆H₁₃N₃O₂

(E)-3-(4-(tert-Butyl)phenyl)-2-cyano-N-(6-methylpyridin-2-yl)acrylamide chemical structure, C20H21N3O, CAS 496021-27-3

(E)-3-(4-(tert-Butyl)phenyl)-2-cyano-N-(6-methylpyridin-2-yl)acrylamide

CAS 496021-27-3C₂₀H₂₁N₃O