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Murcko scaffold

2-Thiophen-2-yl-piperazine scaffold

76 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
76
With full pages
3
Scaffold SMILES

c1csc(C2CNCCN2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Thiophen-2-yl-piperazine page
Murcko scaffold c1csc(C2CNCCN2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 76 chemicals

2-Thiophen-2-yl-piperazine chemical structure, C8H12N2S, CAS 85803-49-2
2-Thiophen-2-yl-piperazine
CAS 85803-49-2C8H12N2S
Ethyl 3-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C11H16N2O2S, CAS 85803-50-5
Ethyl 3-(thiophen-2-yl)piperazine-1-carboxylate
CAS 85803-50-5C11H16N2O2S
1-Methyl-3-(thiophen-2-yl)piperazine chemical structure, C9H14N2S, CAS 85803-52-7
1-Methyl-3-(thiophen-2-yl)piperazine
CAS 85803-52-7C9H14N2S
tert-Butyl 3-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H20N2O2S, CAS 886771-38-6
tert-Butyl 3-(thiophen-2-yl)piperazine-1-carboxylate
CAS 886771-38-6C13H20N2O2S
2-(5-Chloro-2-thienyl)piperazine chemical structure, C8H11ClN2S, CAS 111760-39-5
2-(5-Chloro-2-thienyl)piperazine
CAS 111760-39-5C8H11ClN2S
2-(3-Methylthiophen-2-yl)piperazine chemical structure, C9H14N2S, CAS 111760-31-7
2-(3-Methylthiophen-2-yl)piperazine
CAS 111760-31-7C9H14N2S
2-(5-Methylthiophen-2-yl)piperazine chemical structure, C9H14N2S, CAS 111760-40-8
2-(5-Methylthiophen-2-yl)piperazine
CAS 111760-40-8C9H14N2S
2-(4-Methylthiophen-2-yl)piperazine chemical structure, C9H14N2S, CAS 111760-41-9
2-(4-Methylthiophen-2-yl)piperazine
CAS 111760-41-9C9H14N2S
2-(5-Bromothiophen-2-yl)piperazine chemical structure, C8H11BrN2S, CAS 111760-29-3
2-(5-Bromothiophen-2-yl)piperazine
CAS 111760-29-3C8H11BrN2S
(R)-2-(Thiophen-2-yl)piperazine chemical structure, C8H12N2S, CAS 1212855-86-1
(R)-2-(Thiophen-2-yl)piperazine
CAS 1212855-86-1C8H12N2S
(S)-2-(Thiophen-2-yl)piperazine chemical structure, C8H12N2S, CAS 1213957-52-8
(S)-2-(Thiophen-2-yl)piperazine
CAS 1213957-52-8C8H12N2S
tert-Butyl (R)-3-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H20N2O2S, CAS 1240586-11-1
tert-Butyl (R)-3-(thiophen-2-yl)piperazine-1-carboxylate
CAS 1240586-11-1C13H20N2O2S
tert-Butyl (S)-3-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H20N2O2S, CAS 1240586-20-2
tert-Butyl (S)-3-(thiophen-2-yl)piperazine-1-carboxylate
CAS 1240586-20-2C13H20N2O2S
1-Methyl-2-(thiophen-2-yl)piperazine chemical structure, C9H14N2S, CAS 1018645-67-4
1-Methyl-2-(thiophen-2-yl)piperazine
CAS 1018645-67-4C9H14N2S
1-Ethyl-3-(2-thienyl)piperazine chemical structure, C10H16N2S, CAS 1248908-16-8
1-Ethyl-3-(2-thienyl)piperazine
CAS 1248908-16-8C10H16N2S
2-(Thiophen-2-yl)piperazine dihydrochloride chemical structure, C8H14Cl2N2S, CAS 1351590-47-0
2-(Thiophen-2-yl)piperazine dihydrochloride
CAS 1351590-47-0C8H14Cl2N2S
2-Thiophen-2-YL-piperazine-1-carboxylic acid tert-butyl ester chemical structure, C13H20N2O2S, CAS 886771-44-4
2-Thiophen-2-YL-piperazine-1-carboxylic acid tert-butyl ester
CAS 886771-44-4C13H20N2O2S
tert-Butyl (2R)-2-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H20N2O2S, CAS 1240585-53-8
tert-Butyl (2R)-2-(thiophen-2-yl)piperazine-1-carboxylate
CAS 1240585-53-8C13H20N2O2S
tert-Butyl (S)-2-(thiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H20N2O2S, CAS 1240588-22-0
tert-Butyl (S)-2-(thiophen-2-yl)piperazine-1-carboxylate
CAS 1240588-22-0C13H20N2O2S
2-(5-Chlorothiophen-2-yl)-1-methylpiperazine chemical structure, C9H13ClN2S, CAS 1225551-31-4
2-(5-Chlorothiophen-2-yl)-1-methylpiperazine
CAS 1225551-31-4C9H13ClN2S
2-(5-Bromothiophen-2-yl)-1-methylpiperazine chemical structure, C9H13BrN2S, CAS 1226125-82-1
2-(5-Bromothiophen-2-yl)-1-methylpiperazine
CAS 1226125-82-1C9H13BrN2S
2-(4-Bromothiophen-2-yl)-1-methylpiperazine chemical structure, C9H13BrN2S, CAS 1368850-23-0
2-(4-Bromothiophen-2-yl)-1-methylpiperazine
CAS 1368850-23-0C9H13BrN2S
tert-Butyl 3-(5-chlorothiophen-2-yl)piperazine-1-carboxylate chemical structure, C13H19ClN2O2S, CAS 1497150-24-9
tert-Butyl 3-(5-chlorothiophen-2-yl)piperazine-1-carboxylate
CAS 1497150-24-9C13H19ClN2O2S
1-Methyl-2-(5-methylthiophen-2-yl)piperazine chemical structure, C10H16N2S, CAS 1368350-65-5
1-Methyl-2-(5-methylthiophen-2-yl)piperazine
CAS 1368350-65-5C10H16N2S