Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Octahydropyrrolo[1,2-a]piperazin-6-one scaffold

36 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 10
Chemicals: 36
With full pages: 4

Scaffold SMILES

O=C1CCC2CNCCN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the Octahydropyrrolo[1,2-a]piperazin-6-one page

Murcko scaffold O=C1CCC2CNCCN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

(7R,8aR)-7-Methylhexahydropyrrolo[1,2-a]pyrazin-6(2H)-one chemical structure, C8H14N2O, CAS 272786-83-1

(7R,8aR)-7-Methylhexahydropyrrolo[1,2-a]pyrazin-6(2H)-one

CAS 272786-83-1C₈H₁₄N₂O

(7S,8aR)-7-Methyl-2,3,4,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-6-one chemical structure, C8H14N2O, CAS 272786-82-0

(7S,8aR)-7-Methyl-2,3,4,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-6-one

CAS 272786-82-0C₈H₁₄N₂O

Octahydropyrrolo[1,2-a]piperazin-6-one chemical structure, C7H12N2O, CAS 117810-52-3

Octahydropyrrolo[1,2-a]piperazin-6-one

CAS 117810-52-3C₇H₁₂N₂O

(R)-Hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one chemical structure, C7H12N2O, CAS 151763-89-2

(R)-Hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one

CAS 151763-89-2C₇H₁₂N₂O

(S)-Hexahydropyrrolo[1,2-A]pyrazin-6(2H)-one chemical structure, C7H12N2O, CAS 151763-88-1

(S)-Hexahydropyrrolo[1,2-A]pyrazin-6(2H)-one

CAS 151763-88-1C₇H₁₂N₂O

7-Methyl-octahydropyrrolo(1,2-a)piperazin-6-one chemical structure, C8H14N2O, CAS 200418-23-1

7-Methyl-octahydropyrrolo(1,2-a)piperazin-6-one

CAS 200418-23-1C₈H₁₄N₂O

Octahydropyrrolo[1,2-a]pyrazin-6-one hydrochloride chemical structure, C7H13ClN2O, CAS 1187385-53-0

Octahydropyrrolo[1,2-a]pyrazin-6-one hydrochloride

CAS 1187385-53-0C₇H₁₃ClN₂O

8a-Methylhexahydropyrrolo[1,2-a]pyrazin-6(2H)-one chemical structure, C8H14N2O, CAS 1092478-43-7

8a-Methylhexahydropyrrolo[1,2-a]pyrazin-6(2H)-one

CAS 1092478-43-7C₈H₁₄N₂O

(R)-Hexahydro-pyrrolo[1,2-a]pyrazin-6-one hydrochloride chemical structure, C7H13ClN2O, CAS 1429238-55-0

(R)-Hexahydro-pyrrolo[1,2-a]pyrazin-6-one hydrochloride

CAS 1429238-55-0C₇H₁₃ClN₂O

2-(Prop-2-enoyl)-octahydropyrrolo[1,2-a]piperazin-6-one chemical structure, C10H14N2O2, CAS 1555296-45-1

2-(Prop-2-enoyl)-octahydropyrrolo[1,2-a]piperazin-6-one

CAS 1555296-45-1C₁₀H₁₄N₂O₂

tert-Butyl 6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate chemical structure, C12H20N2O3, CAS 1429200-16-7

tert-Butyl 6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

CAS 1429200-16-7C₁₂H₂₀N₂O₃

(S)-Hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one hydrochloride chemical structure, C7H13ClN2O, CAS 2445347-90-8

(S)-Hexahydropyrrolo[1,2-a]pyrazin-6(2H)-one hydrochloride

CAS 2445347-90-8C₇H₁₃ClN₂O

6-Oxooctahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid chemical structure, C8H12N2O3, CAS 2168835-41-2

6-Oxooctahydropyrrolo[1,2-a]pyrazine-1-carboxylic acid

CAS 2168835-41-2C₈H₁₂N₂O₃

rel-(1R,8aS)-6-oxo-2,3,4,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-1-carboxylic acid chemical structure, C8H12N2O3, CAS 1808250-09-0

rel-(1R,8aS)-6-oxo-2,3,4,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazine-1-carboxylic acid

CAS 1808250-09-0C₈H₁₂N₂O₃

tert-Butyl N-{6-oxo-octahydropyrrolo[1,2-a]piperazin-7-yl}carbamate chemical structure, C12H21N3O3, CAS 1934374-11-4

tert-Butyl N-{6-oxo-octahydropyrrolo[1,2-a]piperazin-7-yl}carbamate

CAS 1934374-11-4C₁₂H₂₁N₃O₃

tert-Butyl (R)-6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate chemical structure, C12H20N2O3, CAS 2412857-06-6

tert-Butyl (R)-6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

CAS 2412857-06-6C₁₂H₂₀N₂O₃

tert-Butyl (S)-6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate chemical structure, C12H20N2O3, CAS 2412856-87-0

tert-Butyl (S)-6-oxohexahydropyrrolo[1,2-a]pyrazine-2(1H)-carboxylate

CAS 2412856-87-0C₁₂H₂₀N₂O₃

7-Amino-2-(propan-2-yl)-octahydropyrrolo[1,2-a]piperazin-6-one dihydrochloride chemical structure, C10H21Cl2N3O, CAS 2125333-31-3

7-Amino-2-(propan-2-yl)-octahydropyrrolo[1,2-a]piperazin-6-one dihydrochloride

CAS 2125333-31-3C₁₀H₂₁Cl₂N₃O

7-Amino-2-(propan-2-yl)-octahydropyrrolo[1,2-a]pyrazin-6-one chemical structure, C10H19N3O, CAS 2125333-30-2

7-Amino-2-(propan-2-yl)-octahydropyrrolo[1,2-a]pyrazin-6-one

CAS 2125333-30-2C₁₀H₁₉N₃O

7-Amino-2-methyl-octahydropyrrolo(1,2-a)piperazin-6-one dihydrochloride chemical structure, C8H17Cl2N3O, CAS 2241138-43-0

7-Amino-2-methyl-octahydropyrrolo(1,2-a)piperazin-6-one dihydrochloride

CAS 2241138-43-0C₈H₁₇Cl₂N₃O

7-Amino-2-methyl-octahydropyrrolo[1,2-a]pyrazin-6-one chemical structure, C8H15N3O, CAS 2166903-57-5

7-Amino-2-methyl-octahydropyrrolo[1,2-a]pyrazin-6-one

CAS 2166903-57-5C₈H₁₅N₃O

7-Amino-2-methylsulfonyl-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one, hydrochloride chemical structure, C8H16ClN3O3S, CAS 2241131-22-4

7-Amino-2-methylsulfonyl-1,3,4,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-6-one, hydrochloride

CAS 2241131-22-4C₈H₁₆ClN₃O₃S

7-Amino-2-methanesulfonyl-octahydropyrrolo[1,2-a]pyrazin-6-one chemical structure, C8H15N3O3S, CAS 2168063-82-7

7-Amino-2-methanesulfonyl-octahydropyrrolo[1,2-a]pyrazin-6-one

CAS 2168063-82-7C₈H₁₅N₃O₃S

2-[4-(Dimethylamino)but-2-enoyl]-octahydropyrrolo[1,2-a]piperazin-6-one chemical structure, C13H21N3O2, CAS 2249690-09-1

2-[4-(Dimethylamino)but-2-enoyl]-octahydropyrrolo[1,2-a]piperazin-6-one

CAS 2249690-09-1C₁₃H₂₁N₃O₂