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Murcko scaffold

Ring system with 5 rings and 27 atoms

3 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
3
With full pages
1
Scaffold SMILES

c1ccc2c(Nc3ccc(Oc4ccn5ncnc5c4)cc3)ncnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(Nc3ccc(Oc4ccn5ncnc5c4)cc3)ncnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

1-(4-((4-([1,2,4]Triazolo[1,5-a]pyrid-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-yl)thiourea chemical structure, C26H26N8O2S, CAS 1429755-58-7
1-(4-((4-([1,2,4]Triazolo[1,5-a]pyrid-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-yl)thiourea
CAS 1429755-58-7C26H26N8O2S
N-[3-Methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-6-nitro-4-quinazolinamine chemical structure, C21H15N7O3, CAS 2307628-66-4
N-[3-Methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-6-nitro-4-quinazolinamine
CAS 2307628-66-4C21H15N7O3
N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)quinazoline-4,6-diamine chemical structure, C21H17N7O, CAS 2307628-67-5
N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)quinazoline-4,6-diamine
CAS 2307628-67-5C21H17N7O