CompoundList
Sign in
Murcko scaffold

2-Phenyl-5,6-dihydro-4H-1,3,4-oxadiazin-5-one scaffold

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
13
With full pages
7
Scaffold SMILES

O=C1COC(c2ccccc2)=NN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-5,6-dihydro-4H-1,3,4-oxadiazin-5-one page
Murcko scaffold O=C1COC(c2ccccc2)=NN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

4-(2-Chloroethyl)-2-(2-hydroxyphenyl)-4H-1,3,4-oxadiazin-5(6H)-one chemical structure, C11H11ClN2O3, CAS 53995-34-9
4-(2-Chloroethyl)-2-(2-hydroxyphenyl)-4H-1,3,4-oxadiazin-5(6H)-one
CAS 53995-34-9C11H11ClN2O3
3-[2-(4-Methylphenyl)-5-oxo-5,6-dihydro-4H-1,3,4-oxadiazin-4-yl]propanenitrile chemical structure, C13H13N3O2, CAS 861212-61-5
3-[2-(4-Methylphenyl)-5-oxo-5,6-dihydro-4H-1,3,4-oxadiazin-4-yl]propanenitrile
CAS 861212-61-5C13H13N3O2
2-(3-Chlorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one chemical structure, C9H7ClN2O2, CAS 87427-89-2
2-(3-Chlorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one
CAS 87427-89-2C9H7ClN2O2
2-(4-Methoxyphenyl)-4H-1,3,4-oxadiazin-5(6H)-one chemical structure, C10H10N2O3, CAS 87427-90-5
2-(4-Methoxyphenyl)-4H-1,3,4-oxadiazin-5(6H)-one
CAS 87427-90-5C10H10N2O3
2-(4-Fluorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one chemical structure, C9H7FN2O2, CAS 87427-91-6
2-(4-Fluorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one
CAS 87427-91-6C9H7FN2O2
2-(3,5-Dichlorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one chemical structure, C9H6Cl2N2O2, CAS 87427-92-7
2-(3,5-Dichlorophenyl)-4H-1,3,4-oxadiazin-5(6H)-one
CAS 87427-92-7C9H6Cl2N2O2
2-Phenyl-5,6-dihydro-4H-1,3,4-oxadiazin-5-one chemical structure, C9H8N2O2, CAS 28669-17-2
2-Phenyl-5,6-dihydro-4H-1,3,4-oxadiazin-5-one
CAS 28669-17-2C9H8N2O2
2-(4-Aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one chemical structure, C9H9N3O2, CAS 83112-44-1
2-(4-Aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one
CAS 83112-44-1C9H9N3O2
2-(4-Chlorophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one chemical structure, C9H7ClN2O2, CAS 142048-60-0
2-(4-Chlorophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one
CAS 142048-60-0C9H7ClN2O2
2-(4-Bromophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one chemical structure, C9H7BrN2O2, CAS 2126176-84-7
2-(4-Bromophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one
CAS 2126176-84-7C9H7BrN2O2
(2E)-4-[2-(Diethylamino)ethyl]-2-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,3,4-oxadiazinan-5-one--hydrogen chloride (1/1) chemical structure, C15H22ClN3O3, CAS 53995-41-8
(2E)-4-[2-(Diethylamino)ethyl]-2-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,3,4-oxadiazinan-5-one--hydrogen chloride (1/1)
CAS 53995-41-8C15H22ClN3O3
2-(2-Hydroxyphenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one chemical structure, C9H8N2O3, CAS 28669-14-9
2-(2-Hydroxyphenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one
CAS 28669-14-9C9H8N2O3
N-[4-(5-Oxo-4H-1,3,4-oxadiazin-2-yl)phenyl]prop-2-enamide chemical structure, C12H11N3O3, CAS 2361641-75-8
N-[4-(5-Oxo-4H-1,3,4-oxadiazin-2-yl)phenyl]prop-2-enamide
CAS 2361641-75-8C12H11N3O3