Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 28 atoms

48 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 28
Chemicals: 48
With full pages: 6

Scaffold SMILES

O=C(CSc1nnc(-c2ccncc2)n1Cc1ccco1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CSc1nnc(-c2ccncc2)n1Cc1ccco1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

N-(2,6-Dimethyl-phenyl)-2-(4-furan-2-ylmethyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide chemical structure, C22H21N5O2S, CAS 333408-86-9

N-(2,6-Dimethyl-phenyl)-2-(4-furan-2-ylmethyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetamide

CAS 333408-86-9C₂₂H₂₁N₅O₂S

2-(4-Furan-2-ylmethyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(2,4,6-trimethyl-phenyl)-acetamide chemical structure, C23H23N5O2S, CAS 333409-63-5

2-(4-Furan-2-ylmethyl-5-pyridin-4-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-N-(2,4,6-trimethyl-phenyl)-acetamide

CAS 333409-63-5C₂₃H₂₃N₅O₂S

N-(4-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H18ClN5O2S, CAS 573695-88-2

N-(4-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573695-88-2C₂₁H₁₈ClN₅O₂S

N-(2-Chloro-4,6-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C22H20ClN5O2S, CAS 573938-52-0

N-(2-Chloro-4,6-dimethylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-4-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 573938-52-0C₂₂H₂₀ClN₅O₂S

N-(3-Chlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16ClN5O2S, CAS 333408-76-7

N-(3-Chlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333408-76-7C₂₀H₁₆ClN₅O₂S

N-(4-Chlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16ClN5O2S, CAS 333408-82-5

N-(4-Chlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333408-82-5C₂₀H₁₆ClN₅O₂S

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide chemical structure, C21H19N5O2S, CAS 333408-98-3

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methylphenyl)acetamide

CAS 333408-98-3C₂₁H₁₉N₅O₂S

N-(2-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16BrN5O2S, CAS 333409-05-5

N-(2-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333409-05-5C₂₀H₁₆BrN₅O₂S

N-(2-Bromo-4-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H18BrN5O2S, CAS 333409-09-9

N-(2-Bromo-4-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333409-09-9C₂₁H₁₈BrN₅O₂S

N-(4-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O3S, CAS 333409-26-0

N-(4-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333409-26-0C₂₂H₂₁N₅O₃S

N-(3-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H18ClN5O2S, CAS 333409-55-5

N-(3-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333409-55-5C₂₁H₁₈ClN₅O₂S

N-(4-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 333409-71-5

N-(4-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 333409-71-5C₂₂H₂₁N₅O₂S

N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H15ClF3N5O2S, CAS 485338-15-6

N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 485338-15-6C₂₁H₁₅ClF₃N₅O₂S

N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H20ClN5O3S, CAS 573945-46-7

N-(4-Chloro-2-methoxy-5-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573945-46-7C₂₂H₂₀ClN₅O₃S

N-(3-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16BrN5O2S, CAS 723327-35-3

N-(3-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 723327-35-3C₂₀H₁₆BrN₅O₂S

N-(2-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O3S, CAS 573949-81-2

N-(2-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573949-81-2C₂₂H₂₁N₅O₃S

N-(4-Bromo-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H18BrN5O2S, CAS 723326-26-9

N-(4-Bromo-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 723326-26-9C₂₁H₁₈BrN₅O₂S

N-(2-Ethyl-6-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C23H23N5O2S, CAS 767309-77-3

N-(2-Ethyl-6-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 767309-77-3C₂₃H₂₃N₅O₂S

N-[5-(Acetylamino)-2-methoxyphenyl]-2-[4-(2-furylmethyl)-5-(4-pyridyl)(1,2,4-t riazol-3-ylthio)]acetamide chemical structure, C23H22N6O4S, CAS 577982-89-9

N-[5-(Acetylamino)-2-methoxyphenyl]-2-[4-(2-furylmethyl)-5-(4-pyridyl)(1,2,4-t riazol-3-ylthio)]acetamide

CAS 577982-89-9C₂₃H₂₂N₆O₄S

N-(3,5-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 578001-01-1

N-(3,5-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 578001-01-1C₂₂H₂₁N₅O₂S

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide chemical structure, C21H19N5O3S, CAS 578003-12-0

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(3-methoxyphenyl)acetamide

CAS 578003-12-0C₂₁H₁₉N₅O₃S

N-(2-Bromo-4,6-difluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H14BrF2N5O2S, CAS 578756-54-4

N-(2-Bromo-4,6-difluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 578756-54-4C₂₀H₁₄BrF₂N₅O₂S

N-(2-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 575466-77-2

N-(2-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 575466-77-2C₂₂H₂₁N₅O₂S

N-(2,4-Difluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H15F2N5O2S, CAS 575460-43-4

N-(2,4-Difluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 575460-43-4C₂₀H₁₅F₂N₅O₂S