Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 28 atoms

39 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 28
Chemicals: 39
With full pages: 5

Scaffold SMILES

O=C(CSc1nnc(-c2ccccn2)n1Cc1ccco1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CSc1nnc(-c2ccccn2)n1Cc1ccco1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

2-[[4-(Furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-5-methylphenyl)acetamide chemical structure, C22H21N5O3S, CAS 841207-89-4

2-[[4-(Furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(2-methoxy-5-methylphenyl)acetamide

CAS 841207-89-4C₂₂H₂₁N₅O₃S

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide chemical structure, C21H19N5O3S, CAS 573693-48-8

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-methoxyphenyl)acetamide

CAS 573693-48-8C₂₁H₁₉N₅O₃S

N-(2-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O3S, CAS 577999-79-2

N-(2-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 577999-79-2C₂₂H₂₁N₅O₃S

N-(4-Chloro-2-methoxy-5-methylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C22H20ClN5O3S, CAS 573947-98-5

N-(4-Chloro-2-methoxy-5-methylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 573947-98-5C₂₂H₂₀ClN₅O₃S

N-(3-Chloro-2-methylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C21H18ClN5O2S, CAS 577983-12-1

N-(3-Chloro-2-methylphenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 577983-12-1C₂₁H₁₈ClN₅O₂S

N-(4-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C21H18ClN5O2S, CAS 573942-32-2

N-(4-Chloro-2-methylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573942-32-2C₂₁H₁₈ClN₅O₂S

N-(3,4-Dichlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H15Cl2N5O2S, CAS 680599-40-0

N-(3,4-Dichlorophenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 680599-40-0C₂₀H₁₅Cl₂N₅O₂S

N-(2,5-Dichlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H15Cl2N5O2S, CAS 573971-48-9

N-(2,5-Dichlorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573971-48-9C₂₀H₁₅Cl₂N₅O₂S

N-(4-Acetamidophenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C22H20N6O3S, CAS 585553-09-9

N-(4-Acetamidophenyl)-2-[[4-(furan-2-ylmethyl)-5-pyridin-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 585553-09-9C₂₂H₂₀N₆O₃S

N-[5-(Acetylamino)-2-methoxyphenyl]-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C23H22N6O4S, CAS 573937-69-6

N-[5-(Acetylamino)-2-methoxyphenyl]-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573937-69-6C₂₃H₂₂N₆O₄S

N-(4-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16BrN5O2S, CAS 679822-29-8

N-(4-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 679822-29-8C₂₀H₁₆BrN₅O₂S

2-[4-(2-Furylmethyl)-5-(2-pyridyl)(1,2,4-triazol-3-ylthio)]-N-(4-methylphenyl) acetamide chemical structure, C21H19N5O2S, CAS 840487-04-9

2-[4-(2-Furylmethyl)-5-(2-pyridyl)(1,2,4-triazol-3-ylthio)]-N-(4-methylphenyl) acetamide

CAS 840487-04-9C₂₁H₁₉N₅O₂S

N-(3-Chloro-4-fluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H15ClFN5O2S, CAS 577982-85-5

N-(3-Chloro-4-fluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 577982-85-5C₂₀H₁₅ClFN₅O₂S

N-(2-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 577984-07-7

N-(2-Ethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 577984-07-7C₂₂H₂₁N₅O₂S

N-(3,5-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 752986-01-9

N-(3,5-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 752986-01-9C₂₂H₂₁N₅O₂S

N-(3,4-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S, CAS 573695-55-3

N-(3,4-Dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 573695-55-3C₂₂H₂₁N₅O₂S

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-sulfamoylphenyl)acetamide chemical structure, C20H18N6O4S2, CAS 573696-25-0

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-sulfamoylphenyl)acetamide

CAS 573696-25-0C₂₀H₁₈N₆O₄S₂

Methyl 4-[({[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzoate chemical structure, C22H19N5O4S, CAS 578747-41-8

Methyl 4-[({[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzoate

CAS 578747-41-8C₂₂H₁₉N₅O₄S

N-(3-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16BrN5O2S, CAS 679424-91-0

N-(3-Bromophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 679424-91-0C₂₀H₁₆BrN₅O₂S

N-(4-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O3S, CAS 577788-51-3

N-(4-Ethoxyphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 577788-51-3C₂₂H₂₁N₅O₃S

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide chemical structure, C21H19N5O3S, CAS 577962-01-7

2-{[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-methoxyphenyl)acetamide

CAS 577962-01-7C₂₁H₁₉N₅O₃S

4-[({[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzamide chemical structure, C21H18N6O3S, CAS 577963-78-1

4-[({[4-(Furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzamide

CAS 577963-78-1C₂₁H₁₈N₆O₃S

N-(4-Fluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H16FN5O2S, CAS 585551-76-4

N-(4-Fluorophenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 585551-76-4C₂₀H₁₆FN₅O₂S

N-(2-Chloro-4,6-dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H20ClN5O2S, CAS 579442-36-7

N-(2-Chloro-4,6-dimethylphenyl)-2-{[4-(furan-2-ylmethyl)-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide

CAS 579442-36-7C₂₂H₂₀ClN₅O₂S