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Murcko scaffold

Ring system with 4 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
8
With full pages
1
Scaffold SMILES

C1=C(c2ccccc2)Nc2nnnn2C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=C(c2ccccc2)Nc2nnnn2C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

5-(3,4-Dimethylphenyl)-7-(3-nitrophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C18H16N6O2, CAS 827013-53-6
5-(3,4-Dimethylphenyl)-7-(3-nitrophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 827013-53-6C18H16N6O2
7-(3,4-Dimethoxyphenyl)-5-(3-methoxyphenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C19H19N5O3, CAS 671766-74-8
7-(3,4-Dimethoxyphenyl)-5-(3-methoxyphenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 671766-74-8C19H19N5O3
5-(3-Methoxyphenyl)-7-(2,3,4-trimethoxyphenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C20H21N5O4, CAS 698379-27-0
5-(3-Methoxyphenyl)-7-(2,3,4-trimethoxyphenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 698379-27-0C20H21N5O4
5-(4-Chlorophenyl)-7-(4-ethylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C18H16ClN5, CAS 672265-00-8
5-(4-Chlorophenyl)-7-(4-ethylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 672265-00-8C18H16ClN5
5-(4-Chlorophenyl)-7-(4-methylphenyl)-4,7-dihydrotetraazolo[1,5-a]pyrimidine chemical structure, C17H14ClN5, CAS 578751-00-5
5-(4-Chlorophenyl)-7-(4-methylphenyl)-4,7-dihydrotetraazolo[1,5-a]pyrimidine
CAS 578751-00-5C17H14ClN5
5-(3-Chloro-4-ethoxyphenyl)-7-[2-(difluoromethoxy)phenyl]-4,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C19H16ClF2N5O2, CAS 6207-33-6
5-(3-Chloro-4-ethoxyphenyl)-7-[2-(difluoromethoxy)phenyl]-4,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 6207-33-6C19H16ClF2N5O2
7-(2,3-Dimethoxyphenyl)-5-(4-ethylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C20H21N5O2, CAS 6211-01-4
7-(2,3-Dimethoxyphenyl)-5-(4-ethylphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 6211-01-4C20H21N5O2
5-(4-Ethylphenyl)-7-(2-fluorophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine chemical structure, C18H16FN5, CAS 6203-68-5
5-(4-Ethylphenyl)-7-(2-fluorophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine
CAS 6203-68-5C18H16FN5