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Murcko scaffold

Ring system with 4 rings and 21 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
6
With full pages
1
Scaffold SMILES

c1ccc(C2CC(c3ccccc3)n3nnnc3N2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CC(c3ccccc3)n3nnnc3N2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-(3-Bromophenyl)-7-phenyl-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine chemical structure, C16H14BrN5, CAS 683798-92-7
5-(3-Bromophenyl)-7-phenyl-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine
CAS 683798-92-7C16H14BrN5
Hbf-0259 chemical structure, C16H12Cl2FN5, CAS 957011-15-3
Hbf-0259
CAS 957011-15-3C16H12Cl2FN5
7-(2,3-Dimethoxyphenyl)-5-(4-iodophenyl)-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine chemical structure, C18H18IN5O2, CAS 6769-73-9
7-(2,3-Dimethoxyphenyl)-5-(4-iodophenyl)-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine
CAS 6769-73-9C18H18IN5O2
7-(4-Chlorophenyl)-5-(3,4-dimethylphenyl)-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine chemical structure, C18H18ClN5, CAS 6769-97-7
7-(4-Chlorophenyl)-5-(3,4-dimethylphenyl)-1,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine
CAS 6769-97-7C18H18ClN5
7-(3,4-Dichlorophenyl)-5-(3,4-dimethoxyphenyl)-4,5,6,7-tetrahydrotetraazolo[1,5-a]pyrimidine chemical structure, C18H17Cl2N5O2, CAS 903189-42-4
7-(3,4-Dichlorophenyl)-5-(3,4-dimethoxyphenyl)-4,5,6,7-tetrahydrotetraazolo[1,5-a]pyrimidine
CAS 903189-42-4C18H17Cl2N5O2
5-(3,4-Dimethoxyphenyl)-7-(2-fluorophenyl)-4,5,6,7-tetrahydrotetraazolo[1,5-a]pyrimidine chemical structure, C18H18FN5O2, CAS 903184-11-2
5-(3,4-Dimethoxyphenyl)-7-(2-fluorophenyl)-4,5,6,7-tetrahydrotetraazolo[1,5-a]pyrimidine
CAS 903184-11-2C18H18FN5O2