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Murcko scaffold

3,4-Dihydro-1-(phenylmethyl)isoquinoline scaffold

69 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
69
With full pages
9
Scaffold SMILES

c1ccc(CC2=NCCc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,4-Dihydro-1-(phenylmethyl)isoquinoline page
Murcko scaffold c1ccc(CC2=NCCc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 69 chemicals

1-[(3,4-Diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline chemical structure, C24H31NO4, CAS 861-27-8
1-[(3,4-Diethoxyphenyl)methyl]-6,7-diethoxy-3,4-dihydroisoquinoline
CAS 861-27-8C24H31NO4
Isoquinolinium, 3,4-dihydro-6,7-dimethoxy-2-methyl-1-veratryl-, iodide chemical structure, C21H26INO4, CAS 3947-79-3
Isoquinolinium, 3,4-dihydro-6,7-dimethoxy-2-methyl-1-veratryl-, iodide
CAS 3947-79-3C21H26INO4
2-Methyl-3,4-dihydropapaverinium chemical structure, C21H26NO4+, CAS 96550-47-9
2-Methyl-3,4-dihydropapaverinium
CAS 96550-47-9C21H26NO4+
1-((3,4-Dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxyisoquinoline chemical structure, C20H23NO4, CAS 6957-27-3
1-((3,4-Dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxyisoquinoline
CAS 6957-27-3C20H23NO4
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(o-fluorobenzyl)-, hydrobromide chemical structure, C18H19BrFNO2, CAS 10268-23-2
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(o-fluorobenzyl)-, hydrobromide
CAS 10268-23-2C18H19BrFNO2
3,4-Dihydro-1-(phenylmethyl)isoquinoline chemical structure, C16H15N, CAS 24853-83-6
3,4-Dihydro-1-(phenylmethyl)isoquinoline
CAS 24853-83-6C16H15N
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(p-fluorobenzyl)-, hydrobromide chemical structure, C18H19BrFNO2, CAS 36113-30-1
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(p-fluorobenzyl)-, hydrobromide
CAS 36113-30-1C18H19BrFNO2
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(m-fluorobenzyl)-, hydrobromide chemical structure, C18H19BrFNO2, CAS 36113-31-2
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-(m-fluorobenzyl)-, hydrobromide
CAS 36113-31-2C18H19BrFNO2
1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline--hydrogen bromide (1/1) chemical structure, C20H24BrNO4, CAS 57543-00-7
1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline--hydrogen bromide (1/1)
CAS 57543-00-7C20H24BrNO4
1-((2-Bromo-4,5-dimethoxyphenyl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline--hydrogen chloride (1/1) chemical structure, C20H23BrClNO4, CAS 59444-56-3
1-((2-Bromo-4,5-dimethoxyphenyl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline--hydrogen chloride (1/1)
CAS 59444-56-3C20H23BrClNO4
6'-Bromodihydropapaverine chemical structure, C20H22BrNO4, CAS 41823-67-0
6'-Bromodihydropapaverine
CAS 41823-67-0C20H22BrNO4
Diproteverine chemical structure, C26H35NO4, CAS 69373-95-1
Diproteverine
CAS 69373-95-1C26H35NO4
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-((4,5-dimethoxy-2-iodo)benzyl)-, hydrochloride chemical structure, C20H23ClINO4, CAS 73168-81-7
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-((4,5-dimethoxy-2-iodo)benzyl)-, hydrochloride
CAS 73168-81-7C20H23ClINO4
Isoquinolinium, 3,4-dihydro-6,7-dimethoxy-1-((4,5-dimethoxy-2-iodophenyl)methyl)-2-methyl-, iodide chemical structure, C21H25I2NO4, CAS 74411-75-9
Isoquinolinium, 3,4-dihydro-6,7-dimethoxy-1-((4,5-dimethoxy-2-iodophenyl)methyl)-2-methyl-, iodide
CAS 74411-75-9C21H25I2NO4
Drotaverine, acephyllinate drug combination chemical structure, C33H41N5O8, CAS 61954-97-0
Drotaverine, acephyllinate drug combination
CAS 61954-97-0C33H41N5O8
6,7-Dimethoxy-1-(4-nitrobenzyl)-3,4-dihydroisoquinoline chemical structure, C18H18N2O4, CAS 10268-39-0
6,7-Dimethoxy-1-(4-nitrobenzyl)-3,4-dihydroisoquinoline
CAS 10268-39-0C18H18N2O4
1-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline chemical structure, C20H22N2O6, CAS 16251-41-5
1-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline
CAS 16251-41-5C20H22N2O6
6,7-Isoquinolinediol, 1-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro- chemical structure, C16H15NO4, CAS 56632-95-2
6,7-Isoquinolinediol, 1-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-
CAS 56632-95-2C16H15NO4
1-Benzyl-6,7-dimethoxy-3,4-dihydro-isoquinoline chemical structure, C18H19NO2, CAS 4876-00-0
1-Benzyl-6,7-dimethoxy-3,4-dihydro-isoquinoline
CAS 4876-00-0C18H19NO2
6,7-Dimethoxy-1-(3-methoxybenzyl)-3,4-dihydroisoquinoline chemical structure, C19H21NO3, CAS 1860-59-9
6,7-Dimethoxy-1-(3-methoxybenzyl)-3,4-dihydroisoquinoline
CAS 1860-59-9C19H21NO3
1,2-Dehydroreticuline chemical structure, C19H22NO4+, CAS 16202-17-8
1,2-Dehydroreticuline
CAS 16202-17-8C19H22NO4+
3',4'-Desoxy-3,4-dihydropapaveroline chemical structure, C16H15NO2, CAS 17578-74-4
3',4'-Desoxy-3,4-dihydropapaveroline
CAS 17578-74-4C16H15NO2
3,4-Dihydroisoquinoline, 1-[3-hydroxybenzyl]-6-methoxy- chemical structure, C17H17NO2, CAS 84375-15-5
3,4-Dihydroisoquinoline, 1-[3-hydroxybenzyl]-6-methoxy-
CAS 84375-15-5C17H17NO2
3,4-Dihydroisoquinolin-7-ol, 1-[4-hydroxybenzyl]-6-methoxy- chemical structure, C17H17NO3, CAS 47145-46-0
3,4-Dihydroisoquinolin-7-ol, 1-[4-hydroxybenzyl]-6-methoxy-
CAS 47145-46-0C17H17NO3