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Murcko scaffold

Ring system with 4 rings and 24 atoms

15 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
15
With full pages
1
Scaffold SMILES

O=C1CC(Sc2ncc3ccccc3n2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(Sc2ncc3ccccc3n2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

3-[(4,7-Dimethylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C21H19N3O3S, CAS 335210-94-1
3-[(4,7-Dimethylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 335210-94-1C21H19N3O3S
1-(3,4-Dimethylphenyl)-3-((6-methoxy-4-methyl-2-quinazolinyl)thio)-2,5-pyrrolidinedione chemical structure, C22H21N3O3S, CAS 378207-06-8
1-(3,4-Dimethylphenyl)-3-((6-methoxy-4-methyl-2-quinazolinyl)thio)-2,5-pyrrolidinedione
CAS 378207-06-8C22H21N3O3S
1-(3-Chloro-4-methylphenyl)-3-(4,7-dimethylquinazolin-2-yl)sulfanylpyrrolidine-2,5-dione chemical structure, C21H18ClN3O2S, CAS 364617-74-3
1-(3-Chloro-4-methylphenyl)-3-(4,7-dimethylquinazolin-2-yl)sulfanylpyrrolidine-2,5-dione
CAS 364617-74-3C21H18ClN3O2S
1-(3-Methoxyphenyl)-3-[(4,6,7-trimethylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C22H21N3O3S, CAS 384797-10-8
1-(3-Methoxyphenyl)-3-[(4,6,7-trimethylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 384797-10-8C22H21N3O3S
3-[(6-Ethoxy-4-methylquinazolin-2-yl)sulfanyl]-1-phenylpyrrolidine-2,5-dione chemical structure, C21H19N3O3S, CAS 371217-18-4
3-[(6-Ethoxy-4-methylquinazolin-2-yl)sulfanyl]-1-phenylpyrrolidine-2,5-dione
CAS 371217-18-4C21H19N3O3S
3-[(6-Ethoxy-4-methylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C22H21N3O4S, CAS 385420-67-7
3-[(6-Ethoxy-4-methylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 385420-67-7C22H21N3O4S
1-(4-Ethoxyphenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C22H21N3O4S, CAS 384797-63-1
1-(4-Ethoxyphenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 384797-63-1C22H21N3O4S
1-(4-Fluorophenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C20H16FN3O3S, CAS 371125-58-5
1-(4-Fluorophenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 371125-58-5C20H16FN3O3S
1-(2-Iodophenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C20H16IN3O3S, CAS 370582-41-5
1-(2-Iodophenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 370582-41-5C20H16IN3O3S
1-(2-Ethoxyphenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C22H21N3O4S, CAS 497245-32-6
1-(2-Ethoxyphenyl)-3-[(6-methoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 497245-32-6C22H21N3O4S
1-(3-Chloro-4-methylphenyl)-3-[(4,6,7-trimethyl-2-quinazolinyl)sulfanyl]-2,5-pyrrolidinedione chemical structure, C22H20ClN3O2S, CAS 644959-83-1
1-(3-Chloro-4-methylphenyl)-3-[(4,6,7-trimethyl-2-quinazolinyl)sulfanyl]-2,5-pyrrolidinedione
CAS 644959-83-1C22H20ClN3O2S
1-(4-Fluorophenyl)-3-[(4,6,7-trimethyl-2-quinazolinyl)sulfanyl]-2,5-pyrrolidinedione chemical structure, C21H18FN3O2S, CAS 579440-19-0
1-(4-Fluorophenyl)-3-[(4,6,7-trimethyl-2-quinazolinyl)sulfanyl]-2,5-pyrrolidinedione
CAS 579440-19-0C21H18FN3O2S
1-(4-Methoxyphenyl)-3-[(4,6,7-trimethylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C22H21N3O3S, CAS 585557-46-6
1-(4-Methoxyphenyl)-3-[(4,6,7-trimethylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 585557-46-6C22H21N3O3S
1-(3,4-Dimethylphenyl)-3-[(6-ethoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione chemical structure, C23H23N3O3S, CAS 573975-43-6
1-(3,4-Dimethylphenyl)-3-[(6-ethoxy-4-methylquinazolin-2-yl)sulfanyl]pyrrolidine-2,5-dione
CAS 573975-43-6C23H23N3O3S
3-[(6-Methoxy-4-methylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C21H19N3O4S, CAS 378207-74-0
3-[(6-Methoxy-4-methylquinazolin-2-yl)sulfanyl]-1-(4-methoxyphenyl)pyrrolidine-2,5-dione
CAS 378207-74-0C21H19N3O4S