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Murcko scaffold

Ring system with 4 rings and 25 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(Nc1ccc(Oc2cccnc2)nc1)N1CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(Oc2cccnc2)nc1)N1CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

SB 243213 chemical structure, C22H19F3N4O2, CAS 200940-22-3
SB 243213
CAS 200940-22-3C22H19F3N4O2
SB-242084 chemical structure, C21H19ClN4O2, CAS 181632-25-7
SB-242084
CAS 181632-25-7C21H19ClN4O2
1H-Indole-1-carboxamide, 2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-, hydrochloride (1:1) chemical structure, C22H20ClF3N4O2, CAS 200940-23-4
1H-Indole-1-carboxamide, 2,3-dihydro-5-methyl-N-[6-[(2-methyl-3-pyridinyl)oxy]-3-pyridinyl]-6-(trifluoromethyl)-, hydrochloride (1:1)
CAS 200940-23-4C22H20ClF3N4O2
6-Chloro-5-methyl-N-(6-((2-methyl-3-pyridinyl)oxy)-3-pyridinyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride chemical structure, C21H21Cl3N4O2, CAS 1049747-87-6
6-Chloro-5-methyl-N-(6-((2-methyl-3-pyridinyl)oxy)-3-pyridinyl)-2,3-dihydro-1H-indole-1-carboxamide dihydrochloride
CAS 1049747-87-6C21H21Cl3N4O2
6-Chloro-5-methyl-1-[[2-(2-methylpyrid-3-yloxy)pyrid-5-yl]carbamoyl]indoline dihydrochloride hydrate chemical structure, C21H23Cl3N4O3
6-Chloro-5-methyl-1-[[2-(2-methylpyrid-3-yloxy)pyrid-5-yl]carbamoyl]indoline dihydrochloride hydrate
C21H23Cl3N4O3
SB 242084 hydrochloride chemical structure, C21H20Cl2N4O2, CAS 1260505-34-7
SB 242084 hydrochloride
CAS 1260505-34-7C21H20Cl2N4O2
Sb 243213 dihydrochloride chemical structure, C22H21Cl2F3N4O2, CAS 1780372-25-9
Sb 243213 dihydrochloride
CAS 1780372-25-9C22H21Cl2F3N4O2