Murcko scaffold
Ring system with 4 rings and 27 atoms
5 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 5
- With full pages
- 5
Scaffold SMILES
O=C(Nc1csc2ccccc12)c1ccc(S(=O)(=O)N2CCCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 5 of 5 chemicals
![Methyl 3-(4-((2-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate chemical structure, C23H24N2O5S2, CAS 683768-10-7](/s/PBOTYLDVENPAIK-UHFFFAOYSA-N.svg)
Methyl 3-(4-((2-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate
CAS 683768-10-7C23H24N2O5S2
![Methyl 3-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate chemical structure, C24H26N2O5S2, CAS 397289-54-2](/s/ZQRGMDRRCFHKPJ-UHFFFAOYSA-N.svg)
Methyl 3-(4-((3,5-dimethylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate
CAS 397289-54-2C24H26N2O5S2
![Methyl 3-(4-(piperidin-1-ylsulfonyl)benzamido)benzo[b]thiophene-2-carboxylate chemical structure, C22H22N2O5S2, CAS 397278-79-4](/s/CBIHPHYQDPYWNF-UHFFFAOYSA-N.svg)
Methyl 3-(4-(piperidin-1-ylsulfonyl)benzamido)benzo[b]thiophene-2-carboxylate
CAS 397278-79-4C22H22N2O5S2
![Methyl 3-(4-((4-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate chemical structure, C23H24N2O5S2, CAS 683768-08-3](/s/FZYHTWKYBHLYJD-UHFFFAOYSA-N.svg)
Methyl 3-(4-((4-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate
CAS 683768-08-3C23H24N2O5S2
![Methyl 3-(4-((3-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate chemical structure, C23H24N2O5S2, CAS 683768-09-4](/s/LUFFHHWOBPCABN-UHFFFAOYSA-N.svg)
Methyl 3-(4-((3-methylpiperidin-1-yl)sulfonyl)benzamido)benzo[b]thiophene-2-carboxylate
CAS 683768-09-4C23H24N2O5S2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2ncccc12](/scaffold/YOOZSXQWGPLESR-UHFFFAOYSA-N/structure.svg)
O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2ncccc124 chemicals
O=C(Nc1ccc(Oc2cccnc2)nc1)N1CCc2ccccc213 chemicals
O=C(CN1CCN(Cc2ccccc2)CC1)N1CCc2ccccc212 chemicals
O=C(c1ccccc1)C1CCN(CCN2C(=O)Cc3ccccc32)CC12 chemicals![Scaffold O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2ccccc12](/scaffold/GCCPYLCLTHXPRB-UHFFFAOYSA-N/structure.svg)
O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2ccccc122 chemicals![Scaffold O=C(C(=O)N1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccccc12](/scaffold/TWDRZUNNYNNDNT-UHFFFAOYSA-N/structure.svg)
O=C(C(=O)N1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccccc122 chemicals![Scaffold O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2cnccc12](/scaffold/WFLDUXYGKGIBTI-UHFFFAOYSA-N/structure.svg)
O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2cnccc122 chemicals![Scaffold O=C(c1ccc(C=Cc2n[nH]c3ccccc23)cc1)N1CCNCC1](/scaffold/YYLKKYCXAOBSRM-UHFFFAOYSA-N/structure.svg)
O=C(c1ccc(C=Cc2n[nH]c3ccccc23)cc1)N1CCNCC12 chemicals
C(=Nc1ccc(Oc2ccccc2)cc1)c1occ2ccccc121 chemical![Scaffold O=C(Nc1c[nH]c2ccccc12)c1ccc(S(=O)(=O)N2CCCCC2)cc1](/scaffold/JDIQKPMCWYGZMH-UHFFFAOYSA-N/structure.svg)
O=C(Nc1c[nH]c2ccccc12)c1ccc(S(=O)(=O)N2CCCCC2)cc11 chemical![Scaffold O=C(Cn1cnc2[nH]c(=O)[nH]c(=O)c21)N1CCN(Cc2ccccc2)CC1](/scaffold/NXTFANVFXZLXOI-UHFFFAOYSA-N/structure.svg)
O=C(Cn1cnc2[nH]c(=O)[nH]c(=O)c21)N1CCN(Cc2ccccc2)CC11 chemical
O=C(Cn1c(=O)oc2ccccc21)N1CCN(S(=O)(=O)c2ccccc2)CC11 chemical