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Murcko scaffold

4-(2-Thienyl)pyrimidine scaffold

249 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
249
With full pages
21
Scaffold SMILES

c1csc(-c2ccncn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Thienyl)pyrimidine page
Murcko scaffold c1csc(-c2ccncn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 249 chemicals

N,N-Dimethyl-2-((4'-(thien-2''-yl)pyrimidin-2'-yl)thio)ethylamine chemical structure, C12H15N3S2, CAS 83726-78-7
N,N-Dimethyl-2-((4'-(thien-2''-yl)pyrimidin-2'-yl)thio)ethylamine
CAS 83726-78-7C12H15N3S2
N-(2''-(Dimethylamino)ethyl)-4-(thien-2'-yl)pyrimidin-2-amine chemical structure, C12H16N4S, CAS 83726-76-5
N-(2''-(Dimethylamino)ethyl)-4-(thien-2'-yl)pyrimidin-2-amine
CAS 83726-76-5C12H16N4S
Ethanamine, N,N-dimethyl-2-((4-(2-thienyl)-2-pyrimidinyl)thio)-, monohydrobromide chemical structure, C12H16BrN3S2, CAS 83726-79-8
Ethanamine, N,N-dimethyl-2-((4-(2-thienyl)-2-pyrimidinyl)thio)-, monohydrobromide
CAS 83726-79-8C12H16BrN3S2
Ethanamine, N,N-dimethyl-2-((4-methyl-6-(2-thienyl)-2-pyrimidinyl)thio)- chemical structure, C13H17N3S2, CAS 109628-21-9
Ethanamine, N,N-dimethyl-2-((4-methyl-6-(2-thienyl)-2-pyrimidinyl)thio)-
CAS 109628-21-9C13H17N3S2
N,N-Dimethyl-2-((5-methyl-4-(2-thienyl)-2-pyrimidinyl)thio)ethanamine chemical structure, C13H17N3S2, CAS 109628-22-0
N,N-Dimethyl-2-((5-methyl-4-(2-thienyl)-2-pyrimidinyl)thio)ethanamine
CAS 109628-22-0C13H17N3S2
N,n-dimethyl-2-(4-methyl-6-thiophen-2-yl-pyrimidin-2-yl)sulfanyl-ethanamine Hydrobromide chemical structure, C13H18BrN3S2, CAS 113669-42-4
N,n-dimethyl-2-(4-methyl-6-thiophen-2-yl-pyrimidin-2-yl)sulfanyl-ethanamine Hydrobromide
CAS 113669-42-4C13H18BrN3S2
N,N-Dimethyl-2-(5'-methyl-4'-thien-2''-ylpyrimidin-2'-ylthioethylamine hydrobromide chemical structure, C13H18BrN3S2, CAS 113669-43-5
N,N-Dimethyl-2-(5'-methyl-4'-thien-2''-ylpyrimidin-2'-ylthioethylamine hydrobromide
CAS 113669-43-5C13H18BrN3S2
N,N-Dimethyl-2-(4'-thien-2''-ylpyrimidin-2'-yl)oxyethylamine hydrobromide chemical structure, C12H16BrN3OS, CAS 113669-45-7
N,N-Dimethyl-2-(4'-thien-2''-ylpyrimidin-2'-yl)oxyethylamine hydrobromide
CAS 113669-45-7C12H16BrN3OS
N-(2''-Dimethylaminoethyl)-4-methylthio-6-thien-2'-ylpyrimidin-2-amine hydrobromide chemical structure, C13H19BrN4S2, CAS 113669-47-9
N-(2''-Dimethylaminoethyl)-4-methylthio-6-thien-2'-ylpyrimidin-2-amine hydrobromide
CAS 113669-47-9C13H19BrN4S2
N-(2''-Dimethylaminoethyl)-2-methylthio-6-thien-2'-ylpyrimidine-4-amine hydrobromide chemical structure, C13H19BrN4S2, CAS 113669-48-0
N-(2''-Dimethylaminoethyl)-2-methylthio-6-thien-2'-ylpyrimidine-4-amine hydrobromide
CAS 113669-48-0C13H19BrN4S2
N-(2-Methyl-6-thiophen-2-ylpyrimidin-4-yl)acetamide chemical structure, C11H11N3OS, CAS 92289-58-2
N-(2-Methyl-6-thiophen-2-ylpyrimidin-4-yl)acetamide
CAS 92289-58-2C11H11N3OS
RefChem:381665 chemical structure, C10H7F3N2S2, CAS 2627-53-4
RefChem:381665
CAS 2627-53-4C10H7F3N2S2
4-(2-Thienyl)-6-(trifluoromethyl)-2-pyrimidinamine chemical structure, C9H6F3N3S, CAS 396-63-4
4-(2-Thienyl)-6-(trifluoromethyl)-2-pyrimidinamine
CAS 396-63-4C9H6F3N3S
4-Chloro-2-methylsulfanyl-6-thiophen-2-ylpyrimidine-5-carbonitrile chemical structure, C10H6ClN3S2, CAS 439808-45-4
4-Chloro-2-methylsulfanyl-6-thiophen-2-ylpyrimidine-5-carbonitrile
CAS 439808-45-4C10H6ClN3S2
4-Methyl-6-(thiophen-2-yl)pyrimidin-2-amine chemical structure, C9H9N3S, CAS 26963-43-9
4-Methyl-6-(thiophen-2-yl)pyrimidin-2-amine
CAS 26963-43-9C9H9N3S
2-((4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid chemical structure, C11H7F3N2O2S2, CAS 505054-60-4
2-((4-(Thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid
CAS 505054-60-4C11H7F3N2O2S2
Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate chemical structure, C12H9F3N2O2S2, CAS 505053-94-1
Methyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate
CAS 505053-94-1C12H9F3N2O2S2
Ethyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate chemical structure, C13H11F3N2O2S2, CAS 505054-22-8
Ethyl 2-((4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetate
CAS 505054-22-8C13H11F3N2O2S2
4-(2-Thienyl)pyrimidine chemical structure, C8H6N2S, CAS 19084-26-5
4-(2-Thienyl)pyrimidine
CAS 19084-26-5C8H6N2S
3-(4-Thiophen-2-yl-6-trifluoromethyl-pyrimidine-2-sulfonyl)-propionic acid chemical structure, C12H9F3N2O4S2, CAS 436088-50-5
3-(4-Thiophen-2-yl-6-trifluoromethyl-pyrimidine-2-sulfonyl)-propionic acid
CAS 436088-50-5C12H9F3N2O4S2
4-(5-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine chemical structure, C9H8ClN3S, CAS 199864-44-3
4-(5-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine
CAS 199864-44-3C9H8ClN3S
4-(5-Bromothiophen-2-yl)-6-methylpyrimidin-2-amine chemical structure, C9H8BrN3S, CAS 26963-44-0
4-(5-Bromothiophen-2-yl)-6-methylpyrimidin-2-amine
CAS 26963-44-0C9H8BrN3S
4-(3-Methylthiophen-2-yl)pyrimidin-2-amine chemical structure, C9H9N3S, CAS 856974-83-9
4-(3-Methylthiophen-2-yl)pyrimidin-2-amine
CAS 856974-83-9C9H9N3S
N-Methyl-N-[4-(2-thienyl)-2-pyrimidinyl]cyanamide chemical structure, C10H8N4S, CAS 866020-16-8
N-Methyl-N-[4-(2-thienyl)-2-pyrimidinyl]cyanamide
CAS 866020-16-8C10H8N4S