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Murcko scaffold

Ring system with 2 rings and 13 atoms

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
31
With full pages
6
Scaffold SMILES

c1ccc(CCc2nncs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCc2nncs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

5-(2-Phenylethyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H11N3S, CAS 39181-40-3
5-(2-Phenylethyl)-1,3,4-thiadiazol-2-amine
CAS 39181-40-3C10H11N3S
2-Ethyl-N-[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]butanamide chemical structure, C16H21N3OS, CAS 713092-05-8
2-Ethyl-N-[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]butanamide
CAS 713092-05-8C16H21N3OS
3-Ethoxy-N-[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]propanamide chemical structure, C15H19N3O2S, CAS 827620-75-7
3-Ethoxy-N-[5-(2-phenylethyl)-1,3,4-thiadiazol-2-yl]propanamide
CAS 827620-75-7C15H19N3O2S
5-(4-Methoxyphenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3OS, CAS 101007-44-7
5-(4-Methoxyphenethyl)-1,3,4-thiadiazol-2-amine
CAS 101007-44-7C11H13N3OS
5-(2-Phenylpropyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S, CAS 100988-20-3
5-(2-Phenylpropyl)-1,3,4-thiadiazol-2-amine
CAS 100988-20-3C11H13N3S
5-[2-(3,4-Dimethoxyphenyl)ethyl]-1,3,4-thiadiazol-2-amine chemical structure, C12H15N3O2S, CAS 299442-02-7
5-[2-(3,4-Dimethoxyphenyl)ethyl]-1,3,4-thiadiazol-2-amine
CAS 299442-02-7C12H15N3O2S
5-[2-(2-Methoxy-phenyl)-ethyl]-[1,3,4]thiadiazol-2-ylamine chemical structure, C11H13N3OS, CAS 299932-80-2
5-[2-(2-Methoxy-phenyl)-ethyl]-[1,3,4]thiadiazol-2-ylamine
CAS 299932-80-2C11H13N3OS
5-[2-(3-Methoxy-phenyl)-ethyl]-[1,3,4]thiadiazol-2-ylamine chemical structure, C11H13N3OS, CAS 100988-16-7
5-[2-(3-Methoxy-phenyl)-ethyl]-[1,3,4]thiadiazol-2-ylamine
CAS 100988-16-7C11H13N3OS
N-Methyl-5-phenethyl-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S, CAS 87410-88-6
N-Methyl-5-phenethyl-1,3,4-thiadiazol-2-amine
CAS 87410-88-6C11H13N3S
5-(2-Methylphenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S, CAS 100988-13-4
5-(2-Methylphenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-13-4C11H13N3S
5-(3-Methylphenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S, CAS 100988-14-5
5-(3-Methylphenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-14-5C11H13N3S
5-(4-Methylphenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H13N3S, CAS 100988-15-6
5-(4-Methylphenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-15-6C11H13N3S
2-Amino-5-(3-chlorophenethyl)-1,3,4-thiadiazole chemical structure, C10H10ClN3S, CAS 100988-17-8
2-Amino-5-(3-chlorophenethyl)-1,3,4-thiadiazole
CAS 100988-17-8C10H10ClN3S
5-(4-Chlorophenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H10ClN3S, CAS 100988-18-9
5-(4-Chlorophenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-18-9C10H10ClN3S
5-(3,4-Dichlorophenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H9Cl2N3S, CAS 100988-19-0
5-(3,4-Dichlorophenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-19-0C10H9Cl2N3S
N-Methyl-5-(2-phenylpropyl)-1,3,4-thiadiazol-2-amine chemical structure, C12H15N3S, CAS 87527-76-2
N-Methyl-5-(2-phenylpropyl)-1,3,4-thiadiazol-2-amine
CAS 87527-76-2C12H15N3S
N-Methyl-5-[2-(4-nitrophenyl)propyl]-1,3,4-thiadiazol-2-amine chemical structure, C12H14N4O2S, CAS 87527-79-5
N-Methyl-5-[2-(4-nitrophenyl)propyl]-1,3,4-thiadiazol-2-amine
CAS 87527-79-5C12H14N4O2S
N-Methyl-5-(2-methyl-2-phenylpropyl)-1,3,4-thiadiazol-2-amine chemical structure, C13H17N3S, CAS 87410-89-7
N-Methyl-5-(2-methyl-2-phenylpropyl)-1,3,4-thiadiazol-2-amine
CAS 87410-89-7C13H17N3S
5-(2-Chlorophenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C10H10ClN3S, CAS 100988-30-5
5-(2-Chlorophenethyl)-1,3,4-thiadiazol-2-amine
CAS 100988-30-5C10H10ClN3S
5-[2-(4-Fluorophenyl)ethyl]-1,3,4-thiadiazol-2-amine chemical structure, C10H10FN3S, CAS 88742-89-6
5-[2-(4-Fluorophenyl)ethyl]-1,3,4-thiadiazol-2-amine
CAS 88742-89-6C10H10FN3S
5-(2-(Trifluoromethyl)phenethyl)-1,3,4-thiadiazol-2-amine chemical structure, C11H10F3N3S, CAS 141421-45-6
5-(2-(Trifluoromethyl)phenethyl)-1,3,4-thiadiazol-2-amine
CAS 141421-45-6C11H10F3N3S
5-[2-(3,4,5-Trimethoxyphenyl)ethyl]-1,3,4-thiadiazol-2-amine chemical structure, C13H17N3O3S, CAS 88742-95-4
5-[2-(3,4,5-Trimethoxyphenyl)ethyl]-1,3,4-thiadiazol-2-amine
CAS 88742-95-4C13H17N3O3S
5-(2-Methyl-1-phenylpropan-2-yl)-1,3,4-thiadiazol-2-amine chemical structure, C12H15N3S, CAS 1032464-22-4
5-(2-Methyl-1-phenylpropan-2-yl)-1,3,4-thiadiazol-2-amine
CAS 1032464-22-4C12H15N3S
2-Amino-5-(2-bromophenethyl)-1,3,4-thiadiazole chemical structure, C10H10BrN3S, CAS 1375068-24-8
2-Amino-5-(2-bromophenethyl)-1,3,4-thiadiazole
CAS 1375068-24-8C10H10BrN3S