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Murcko scaffold

3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one scaffold

38 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
38
With full pages
8
Scaffold SMILES

O=C1NCCn2cccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one page
Murcko scaffold O=C1NCCn2cccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

6-Bromo-2-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C8H9BrN2O, CAS 123257-08-9
6-Bromo-2-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 123257-08-9C8H9BrN2O
2-Methyl-3,4-dihydropyrrolo(1,2-a)pyrazin-1(2H)-one chemical structure, C8H10N2O, CAS 54993-52-1
2-Methyl-3,4-dihydropyrrolo(1,2-a)pyrazin-1(2H)-one
CAS 54993-52-1C8H10N2O
3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C7H8N2O, CAS 54906-42-2
3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 54906-42-2C7H8N2O
Mukanadin C chemical structure, C7H7BrN2O2, CAS 1839104-78-7
Mukanadin C
CAS 1839104-78-7C7H7BrN2O2
6,7-Dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one chemical structure, C7H6Br2N2O2, CAS 219783-00-3
6,7-Dibromo-4-hydroxy-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one
CAS 219783-00-3C7H6Br2N2O2
Longamide B chemical structure, C9H8Br2N2O3, CAS 200264-70-6
Longamide B
CAS 200264-70-6C9H8Br2N2O3
2-Ethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C9H12N2O, CAS 709037-15-0
2-Ethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 709037-15-0C9H12N2O
2-Propyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1-one chemical structure, C10H14N2O, CAS 709037-16-1
2-Propyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1-one
CAS 709037-16-1C10H14N2O
2-Propan-2-yl-3,4-dihydropyrrolo[1,2-a]pyrazin-1-one chemical structure, C10H14N2O, CAS 709037-17-2
2-Propan-2-yl-3,4-dihydropyrrolo[1,2-a]pyrazin-1-one
CAS 709037-17-2C10H14N2O
3-Hydroxy-2,3-dimethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C9H12N2O2, CAS 116212-49-8
3-Hydroxy-2,3-dimethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 116212-49-8C9H12N2O2
2-(2-Aminoethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C9H13N3O, CAS 283604-46-6
2-(2-Aminoethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 283604-46-6C9H13N3O
6-Nitro-3,4-dihydropyrrolo[1,2-A]pyrazin-1(2H)-one chemical structure, C7H7N3O3, CAS 54906-41-1
6-Nitro-3,4-dihydropyrrolo[1,2-A]pyrazin-1(2H)-one
CAS 54906-41-1C7H7N3O3
7-Nitro-3,4-dihydropyrrolo[1,2-A]pyrazin-1(2H)-one chemical structure, C7H7N3O3, CAS 54906-40-0
7-Nitro-3,4-dihydropyrrolo[1,2-A]pyrazin-1(2H)-one
CAS 54906-40-0C7H7N3O3
8-Amino-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C7H9N3O, CAS 952417-61-7
8-Amino-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 952417-61-7C7H9N3O
Ethyl 1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate chemical structure, C10H12N2O3, CAS 1338563-13-5
Ethyl 1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylate
CAS 1338563-13-5C10H12N2O3
Ethyl 8-hydroxy-2-methyl-1-oxo-3,4-dihydropyrrolo[1,2-a]pyrazine-7-carboxylate chemical structure, C11H14N2O4, CAS 701208-31-3
Ethyl 8-hydroxy-2-methyl-1-oxo-3,4-dihydropyrrolo[1,2-a]pyrazine-7-carboxylate
CAS 701208-31-3C11H14N2O4
6-Bromo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one chemical structure, C7H7BrN2O, CAS 1374684-64-6
6-Bromo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one
CAS 1374684-64-6C7H7BrN2O
7-Bromo-1H,2H,3H,4H-pyrrolo(1,2-a)pyrazin-1-one chemical structure, C7H7BrN2O, CAS 736990-40-2
7-Bromo-1H,2H,3H,4H-pyrrolo(1,2-a)pyrazin-1-one
CAS 736990-40-2C7H7BrN2O
7-Iodo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one chemical structure, C7H7IN2O, CAS 1416221-80-1
7-Iodo-3,4-dihydro-2H-pyrrolo[1,2-a]pyrazin-1-one
CAS 1416221-80-1C7H7IN2O
2-Methyl-7-nitro-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C8H9N3O3, CAS 54993-50-9
2-Methyl-7-nitro-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 54993-50-9C8H9N3O3
2-Methyl-6-nitro-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C8H9N3O3, CAS 54993-49-6
2-Methyl-6-nitro-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 54993-49-6C8H9N3O3
4-Methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one chemical structure, C8H10N2O, CAS 1243415-14-6
4-Methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
CAS 1243415-14-6C8H10N2O
Ethyl2-(7-iodo-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)acetate chemical structure, C11H13IN2O3, CAS 1218810-48-0
Ethyl2-(7-iodo-1-oxo-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-4-yl)acetate
CAS 1218810-48-0C11H13IN2O3
7-Bromo-4-methyl-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one chemical structure, C8H9BrN2O, CAS 1869739-39-8
7-Bromo-4-methyl-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-1-one
CAS 1869739-39-8C8H9BrN2O