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Murcko scaffold

Ring system with 3 rings and 24 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(NCCc1c[nH]c2ccccc12)C(=O)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCCc1c[nH]c2ccccc12)C(=O)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-[2-(1H-Indol-3-yl)ethyl]-N'-(1-phenylethyl)oxamide chemical structure, C20H21N3O2, CAS 443325-74-4
N-[2-(1H-Indol-3-yl)ethyl]-N'-(1-phenylethyl)oxamide
CAS 443325-74-4C20H21N3O2
N1-(2-(1H-indol-3-yl)ethyl)-N2-(2-methoxybenzyl)oxalamide chemical structure, C20H21N3O3, CAS 941939-36-2
N1-(2-(1H-indol-3-yl)ethyl)-N2-(2-methoxybenzyl)oxalamide
CAS 941939-36-2C20H21N3O3
N1-(2-(1H-indol-3-yl)ethyl)-N2-(4-fluorobenzyl)oxalamide chemical structure, C19H18FN3O2, CAS 941889-33-4
N1-(2-(1H-indol-3-yl)ethyl)-N2-(4-fluorobenzyl)oxalamide
CAS 941889-33-4C19H18FN3O2
N1-(2-(1H-indol-3-yl)ethyl)-N2-(2-chlorobenzyl)oxalamide chemical structure, C19H18ClN3O2, CAS 941895-48-3
N1-(2-(1H-indol-3-yl)ethyl)-N2-(2-chlorobenzyl)oxalamide
CAS 941895-48-3C19H18ClN3O2
N1-(2-(dimethylamino)-2-(1-methyl-1H-indol-3-yl)ethyl)-N2-(2-methoxybenzyl)oxalamide chemical structure, C23H28N4O3, CAS 1091473-26-5
N1-(2-(dimethylamino)-2-(1-methyl-1H-indol-3-yl)ethyl)-N2-(2-methoxybenzyl)oxalamide
CAS 1091473-26-5C23H28N4O3
N1-(2-chlorobenzyl)-N2-(2-(dimethylamino)-2-(1-methyl-1H-indol-3-yl)ethyl)oxalamide chemical structure, C22H25ClN4O2, CAS 1091395-61-7
N1-(2-chlorobenzyl)-N2-(2-(dimethylamino)-2-(1-methyl-1H-indol-3-yl)ethyl)oxalamide
CAS 1091395-61-7C22H25ClN4O2
N1-(2-hydroxy-2-(1-methyl-1H-indol-3-yl)ethyl)-N2-(1-phenylethyl)oxalamide chemical structure, C21H23N3O3, CAS 1448052-47-8
N1-(2-hydroxy-2-(1-methyl-1H-indol-3-yl)ethyl)-N2-(1-phenylethyl)oxalamide
CAS 1448052-47-8C21H23N3O3
N1-(4-fluorobenzyl)-N2-(2-hydroxy-2-(1-methyl-1H-indol-3-yl)ethyl)oxalamide chemical structure, C20H20FN3O3, CAS 1448131-32-5
N1-(4-fluorobenzyl)-N2-(2-hydroxy-2-(1-methyl-1H-indol-3-yl)ethyl)oxalamide
CAS 1448131-32-5C20H20FN3O3