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Murcko scaffold

Ring system with 3 rings and 24 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
14
With full pages
6
Scaffold SMILES

O=C(CNC(=O)c1ccccc1)NN=Cc1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)c1ccccc1)NN=Cc1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-nitrobenzamide chemical structure, C18H15N5O4, CAS 391891-76-2
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-nitrobenzamide
CAS 391891-76-2C18H15N5O4
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-methyl-3-nitrobenzamide chemical structure, C19H17N5O4, CAS 391892-86-7
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-methyl-3-nitrobenzamide
CAS 391892-86-7C19H17N5O4
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-methyl-3-nitrobenzamide chemical structure, C19H17N5O4, CAS 391892-97-0
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-methyl-3-nitrobenzamide
CAS 391892-97-0C19H17N5O4
N-[1-(2-Methyl-1H-indol-3-yl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-benzamide chemical structure, C19H18N4O2, CAS 373613-54-8
N-[1-(2-Methyl-1H-indol-3-yl)-meth-(E)-ylidene-hydrazinocarbonylmethyl]-benzamide
CAS 373613-54-8C19H18N4O2
(E)-3,4-Dimethoxy-N-(2-(2-((2-methyl-1H-indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide chemical structure, C21H22N4O4, CAS 349568-79-2
(E)-3,4-Dimethoxy-N-(2-(2-((2-methyl-1H-indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)benzamide
CAS 349568-79-2C21H22N4O4
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-3,4,5-triethoxybenzamide chemical structure, C24H28N4O5, CAS 391893-44-0
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-3,4,5-triethoxybenzamide
CAS 391893-44-0C24H28N4O5
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-(N,N-dimethylsulfamoyl)benzamide chemical structure, C20H21N5O4S, CAS 391895-87-7
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-(N,N-dimethylsulfamoyl)benzamide
CAS 391895-87-7C20H21N5O4S
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-(tert-butyl)benzamide chemical structure, C22H24N4O2, CAS 391891-97-7
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-4-(tert-butyl)benzamide
CAS 391891-97-7C22H24N4O2
4-Butoxy-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C22H24N4O3, CAS 391892-19-6
4-Butoxy-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 391892-19-6C22H24N4O3
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-chloro-6-fluorobenzamide chemical structure, C18H14ClFN4O2, CAS 391892-53-8
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-chloro-6-fluorobenzamide
CAS 391892-53-8C18H14ClFN4O2
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-(trifluoromethyl)benzamide chemical structure, C19H15F3N4O2, CAS 391892-64-1
(E)-N-(2-(2-((1H-Indol-3-yl)methylene)hydrazinyl)-2-oxoethyl)-2-(trifluoromethyl)benzamide
CAS 391892-64-1C19H15F3N4O2
3-Bromo-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C18H15BrN4O2, CAS 881403-21-0
3-Bromo-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 881403-21-0C18H15BrN4O2
3,4-Dichloro-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide chemical structure, C18H14Cl2N4O2, CAS 881660-02-2
3,4-Dichloro-N-(2-(2-(1H-indol-3-ylmethylene)hydrazino)-2-oxoethyl)benzamide
CAS 881660-02-2C18H14Cl2N4O2
N-(2-(2-(1H-Indol-3-ylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide chemical structure, C21H22N4O3, CAS 765907-45-7
N-(2-(2-(1H-Indol-3-ylmethylene)hydrazino)-2-oxoethyl)-4-propoxybenzamide
CAS 765907-45-7C21H22N4O3