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Murcko scaffold

Ring system with 4 rings and 22 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(Nc1ccncc1)c1cccc2oc3ccccc3c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccncc1)c1cccc2oc3ccccc3c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

1-Dibenzofurancarboxamide, N-(3,5-dichloro-4-pyridinyl)-4-methoxy- chemical structure, C19H12Cl2N2O3, CAS 685874-42-4
1-Dibenzofurancarboxamide, N-(3,5-dichloro-4-pyridinyl)-4-methoxy-
CAS 685874-42-4C19H12Cl2N2O3
N-(3,5-Dichloropyrid-4-yl)-4-difluoromethoxy-8-nitro-dibenzo[b,d]furan-1-carboxamide chemical structure, C19H9Cl2F2N3O5, CAS 685875-02-9
N-(3,5-Dichloropyrid-4-yl)-4-difluoromethoxy-8-nitro-dibenzo[b,d]furan-1-carboxamide
CAS 685875-02-9C19H9Cl2F2N3O5
N-(3,5-Dichloropyrid-4-yl)-4-difluoromethoxy-8-amino-dibenzo[b,d]furan-1-carboxamide chemical structure, C19H11Cl2F2N3O3, CAS 685875-03-0
N-(3,5-Dichloropyrid-4-yl)-4-difluoromethoxy-8-amino-dibenzo[b,d]furan-1-carboxamide
CAS 685875-03-0C19H11Cl2F2N3O3
4-(Methylthio)-N-4-pyridinyl-1-dibenzofurancarboxamide chemical structure, C19H14N2O2S, CAS 1026370-74-0
4-(Methylthio)-N-4-pyridinyl-1-dibenzofurancarboxamide
CAS 1026370-74-0C19H14N2O2S
Oglemilast chemical structure, C20H13Cl2F2N3O5S, CAS 778576-62-8
Oglemilast
CAS 778576-62-8C20H13Cl2F2N3O5S
Oglemilast sodium chemical structure, C20H12Cl2F2N3NaO5S, CAS 873334-87-3
Oglemilast sodium
CAS 873334-87-3C20H12Cl2F2N3NaO5S
Sodium [9-[(3,5-dichloro-4-pyridinyl)carbamoyl]-6-(difluoromethoxy)dibenzofuran-2-yl]-(methylsulfonimidoyl)azanide chemical structure, C20H13Cl2F2N4NaO4S, CAS 778576-63-9
Sodium [9-[(3,5-dichloro-4-pyridinyl)carbamoyl]-6-(difluoromethoxy)dibenzofuran-2-yl]-(methylsulfonimidoyl)azanide
CAS 778576-63-9C20H13Cl2F2N4NaO4S