Murcko scaffold

2-Oxo-N-phenyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide scaffold

25 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 25
With full pages: 5

Scaffold SMILES

O=C1CC(C(=O)Nc2ccccc2)n2c(nc3ccccc32)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Oxo-N-phenyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide page

Murcko scaffold O=C1CC(C(=O)Nc2ccccc2)n2c(nc3ccccc32)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

N-(2,4-Dimethylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1031378-21-8C₁₉H₁₈N₄O₂

N-(2,4-Dichlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1031378-48-9C₁₇H₁₂Cl₂N₄O₂

N-(4-Isopropylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008014-84-3C₂₀H₂₀N₄O₂

2-Oxo-N-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008014-71-8C₁₈H₁₃F₃N₄O₂

N-(3-Chlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008924-84-2C₁₇H₁₃ClN₄O₂

N-(5-Chloro-2-methylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008465-14-2C₁₈H₁₅ClN₄O₂

N-[4-(Acetylamino)phenyl]-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1009716-52-2C₁₉H₁₇N₅O₃

N-(4-Acetylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1007931-40-9C₁₉H₁₆N₄O₃

N-(3-Fluorophenyl)-2-oxo-4,10-dihydro-3H-pyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008068-51-6C₁₇H₁₃FN₄O₂

N-(3-Chloro-4-fluorophenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1009500-44-0C₁₇H₁₂ClFN₄O₂

N-(2,4-Dimethoxyphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008999-29-8C₁₉H₁₈N₄O₄

N-(2-Fluorophenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1032070-46-4C₁₇H₁₃FN₄O₂

2-Oxo-N-phenyl-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1009664-99-6C₁₇H₁₄N₄O₂

2-Oxo-N-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1008283-69-9C₂₀H₂₀N₄O₅

2-Hydroxy-N-[2-(trifluoromethyl)phenyl]-3,4-dihydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1025705-35-4C₁₈H₁₃F₃N₄O₂

2-Hydroxy-N-(2-methoxyphenyl)-3,4-dihydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1236257-55-8C₁₈H₁₆N₄O₃

4-Methoxy-3-(2-oxo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-carboxamido)benzoic acid

CAS 1246040-91-4C₁₉H₁₆N₄O₅

3-(2-Oxo-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-carboxamido)benzoic acid

CAS 1246041-01-9C₁₈H₁₄N₄O₄

N-(4-Methylphenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1025382-78-8C₁₈H₁₆N₄O₂

N-(2-Chlorophenyl)-2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1093066-90-0C₁₇H₁₃ClN₄O₂

N-(3,4-Difluorophenyl)-2-hydroxy-3,4-dihydropyrimido[1,2-a]benzimidazole-4-carboxamide

CAS 1236260-67-5C₁₇H₁₂F₂N₄O₂

$N-(2,5-Dimethylphenyl)-11-oxo-1,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,9-tetraene-13-carboxamide chemical structure, C19H18N4O2, CAS 1092795-51-1$

N-(2,5-Dimethylphenyl)-11-oxo-1,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,9-tetraene-13-carboxamide

CAS 1092795-51-1C₁₉H₁₈N₄O₂

$Methyl 4-methoxy-3-{11-oxo-1,8,10-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,9-tetraene-13-amido}benzoate chemical structure, C20H18N4O5, CAS 1421445-90-0$