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Murcko scaffold

5-(1H-Imidazol-2-yl)pyrrolidin-2-one scaffold

44 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
44
With full pages
3
Scaffold SMILES

O=C1CCC(c2ncc[nH]2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(1H-Imidazol-2-yl)pyrrolidin-2-one page
Murcko scaffold O=C1CCC(c2ncc[nH]2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

rac-(4R,5S)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride chemical structure, C10H18Cl2N4O, CAS 2307779-95-7
rac-(4R,5S)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride
CAS 2307779-95-7C10H18Cl2N4O
rac-(4R,5S)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 1909287-21-3
rac-(4R,5S)-4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one
CAS 1909287-21-3C10H16N4O
N-{[(2S,3R)-1-methyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidin-3-yl]methyl}prop-2-enamide chemical structure, C13H18N4O2, CAS 2094023-99-9
N-{[(2S,3R)-1-methyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidin-3-yl]methyl}prop-2-enamide
CAS 2094023-99-9C13H18N4O2
rac-(2R,3R)-1-Ethyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 2307780-43-2
rac-(2R,3R)-1-Ethyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 2307780-43-2C11H15N3O3
4-(Aminomethyl)-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one chemical structure, C11H18N4O, CAS 1955518-81-6
4-(Aminomethyl)-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one
CAS 1955518-81-6C11H18N4O
1-Ethyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C11H15N3O3, CAS 1955514-69-8
1-Ethyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 1955514-69-8C11H15N3O3
4-(Aminomethyl)-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride chemical structure, C11H20Cl2N4O, CAS 1955518-82-7
4-(Aminomethyl)-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride
CAS 1955518-82-7C11H20Cl2N4O
4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride chemical structure, C10H18Cl2N4O, CAS 1955531-85-7
4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one dihydrochloride
CAS 1955531-85-7C10H18Cl2N4O
4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 1955523-81-5
4-(Aminomethyl)-1-methyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one
CAS 1955523-81-5C10H16N4O
rac-(2R,3R)-1-Methyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C10H13N3O3, CAS 2307735-99-3
rac-(2R,3R)-1-Methyl-2-(1-methyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 2307735-99-3C10H13N3O3
rac-(2R,3R)-1-Ethyl-2-(1-ethyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O3, CAS 2307772-17-2
rac-(2R,3R)-1-Ethyl-2-(1-ethyl-1H-imidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 2307772-17-2C12H17N3O3
(2S,3S)-1-(2-Methoxyethyl)-2-(1-methylimidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid chemical structure, C12H17N3O4, CAS 2307773-83-5
(2S,3S)-1-(2-Methoxyethyl)-2-(1-methylimidazol-2-yl)-5-oxopyrrolidine-3-carboxylic acid
CAS 2307773-83-5C12H17N3O4
5-(1H-Imidazol-2-yl)pyrrolidin-2-one chemical structure, C7H9N3O, CAS 2358270-07-0
5-(1H-Imidazol-2-yl)pyrrolidin-2-one
CAS 2358270-07-0C7H9N3O
2-Chloro-N-[[(2R,3S)-1-methyl-2-(1-methylimidazol-2-yl)-5-oxopyrrolidin-3-yl]methyl]propanamide chemical structure, C13H19ClN4O2, CAS 2411184-10-4
2-Chloro-N-[[(2R,3S)-1-methyl-2-(1-methylimidazol-2-yl)-5-oxopyrrolidin-3-yl]methyl]propanamide
CAS 2411184-10-4C13H19ClN4O2
Methyl (E)-4-[[(2R,3S)-1-methyl-2-(1-methylimidazol-2-yl)-5-oxopyrrolidin-3-yl]methylamino]-4-oxobut-2-enoate chemical structure, C15H20N4O4, CAS 2411180-90-8
Methyl (E)-4-[[(2R,3S)-1-methyl-2-(1-methylimidazol-2-yl)-5-oxopyrrolidin-3-yl]methylamino]-4-oxobut-2-enoate
CAS 2411180-90-8C15H20N4O4
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-methylpyrrolidin-2-one chemical structure, C8H12N4O, CAS 2227725-87-1
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-methylpyrrolidin-2-one
CAS 2227725-87-1C8H12N4O
rac-(4R,5R)-4-Amino-5-(1-methyl-1H-imidazol-2-yl)-1-propylpyrrolidin-2-one chemical structure, C11H18N4O, CAS 2227641-83-8
rac-(4R,5R)-4-Amino-5-(1-methyl-1H-imidazol-2-yl)-1-propylpyrrolidin-2-one
CAS 2227641-83-8C11H18N4O
4-Amino-5-(1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 2171590-26-2
4-Amino-5-(1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one
CAS 2171590-26-2C10H16N4O
rac-(4R,5R)-4-Amino-5-[1-(propan-2-yl)-1H-imidazol-2-yl]-1-propylpyrrolidin-2-one chemical structure, C13H22N4O, CAS 2227689-40-7
rac-(4R,5R)-4-Amino-5-[1-(propan-2-yl)-1H-imidazol-2-yl]-1-propylpyrrolidin-2-one
CAS 2227689-40-7C13H22N4O
rac-(4R,5R)-4-Amino-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 2227783-10-8
rac-(4R,5R)-4-Amino-1-ethyl-5-(1-methyl-1H-imidazol-2-yl)pyrrolidin-2-one
CAS 2227783-10-8C10H16N4O
rac-(4R,5R)-4-Amino-1-ethyl-5-(4-methyl-1H-imidazol-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 2227832-26-8
rac-(4R,5R)-4-Amino-1-ethyl-5-(4-methyl-1H-imidazol-2-yl)pyrrolidin-2-one
CAS 2227832-26-8C10H16N4O
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one chemical structure, C10H16N4O, CAS 2227831-87-8
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one
CAS 2227831-87-8C10H16N4O
rac-(4R,5R)-4-Amino-5-(1-methyl-1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one chemical structure, C11H18N4O, CAS 2227757-14-2
rac-(4R,5R)-4-Amino-5-(1-methyl-1H-imidazol-2-yl)-1-(propan-2-yl)pyrrolidin-2-one
CAS 2227757-14-2C11H18N4O
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-propylpyrrolidin-2-one chemical structure, C10H16N4O, CAS 2227725-60-0
rac-(4R,5R)-4-Amino-5-(1H-imidazol-2-yl)-1-propylpyrrolidin-2-one
CAS 2227725-60-0C10H16N4O