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Murcko scaffold

Ring system with 2 rings and 12 atoms

91 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
91
With full pages
12
Scaffold SMILES

c1ccc(Nc2cc[nH]n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2cc[nH]n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 91 chemicals

Methyl 3-anilino-5-methyl-1-propanoyl-1H-pyrazole-4-carboxylate chemical structure, C15H17N3O3, CAS 70698-50-9
Methyl 3-anilino-5-methyl-1-propanoyl-1H-pyrazole-4-carboxylate
CAS 70698-50-9C15H17N3O3
RefChem:313890 chemical structure, C12H14N4O2, CAS 61485-23-2
RefChem:313890
CAS 61485-23-2C12H14N4O2
N-(1,3-Dimethyl-5-pyrazolyl)anthranilic acid chemical structure, C12H13N3O2, CAS 34798-68-0
N-(1,3-Dimethyl-5-pyrazolyl)anthranilic acid
CAS 34798-68-0C12H13N3O2
1H-Pyrazol-5-amine, 1-ethyl-3-methyl-N-phenyl- chemical structure, C12H15N3, CAS 847453-88-7
1H-Pyrazol-5-amine, 1-ethyl-3-methyl-N-phenyl-
CAS 847453-88-7C12H15N3
1,5-Dimethyl-N-phenyl-1H-pyrazol-3-amine chemical structure, C11H13N3, CAS 847453-90-1
1,5-Dimethyl-N-phenyl-1H-pyrazol-3-amine
CAS 847453-90-1C11H13N3
1H-Pyrazol-5-amine, 1,3-dimethyl-N-phenyl- chemical structure, C11H13N3, CAS 877168-07-5
1H-Pyrazol-5-amine, 1,3-dimethyl-N-phenyl-
CAS 877168-07-5C11H13N3
5-Amino-3-(phenylamino)-1H-pyrazole-4-carboxamide chemical structure, C10H11N5O, CAS 953806-05-8
5-Amino-3-(phenylamino)-1H-pyrazole-4-carboxamide
CAS 953806-05-8C10H11N5O
4-[(5-Methyl-4-nitro-1H-pyrazol-3-yl)amino]benzoic acid chemical structure, C11H10N4O4, CAS 293764-65-5
4-[(5-Methyl-4-nitro-1H-pyrazol-3-yl)amino]benzoic acid
CAS 293764-65-5C11H10N4O4
4-Nitro-5-(4-iodoanilino)-3-methyl-1H-pyrazole chemical structure, C10H9IN4O2, CAS 414895-90-2
4-Nitro-5-(4-iodoanilino)-3-methyl-1H-pyrazole
CAS 414895-90-2C10H9IN4O2
5-Methyl-4-nitro-N-phenyl-1H-pyrazol-3-amine chemical structure, C10H10N4O2, CAS 312311-39-0
5-Methyl-4-nitro-N-phenyl-1H-pyrazol-3-amine
CAS 312311-39-0C10H10N4O2
5-Methyl-N-(4-methylphenyl)-4-nitro-1H-pyrazol-3-amine chemical structure, C11H12N4O2, CAS 304872-69-3
5-Methyl-N-(4-methylphenyl)-4-nitro-1H-pyrazol-3-amine
CAS 304872-69-3C11H12N4O2
N-(4-Fluorophenyl)-4-nitro-1H-pyrazol-5-amine chemical structure, C9H7FN4O2, CAS 400079-94-9
N-(4-Fluorophenyl)-4-nitro-1H-pyrazol-5-amine
CAS 400079-94-9C9H7FN4O2
5-Amino-3-(4-fluoro-3-methylanilino)-1H-pyrazole-4-carbonitrile chemical structure, C11H10FN5, CAS 1030827-94-1
5-Amino-3-(4-fluoro-3-methylanilino)-1H-pyrazole-4-carbonitrile
CAS 1030827-94-1C11H10FN5
5-Amino-3-(4-fluoro-3-methylanilino)-1-methyl-1H-pyrazole-4-carbonitrile chemical structure, C12H12FN5, CAS 956778-58-8
5-Amino-3-(4-fluoro-3-methylanilino)-1-methyl-1H-pyrazole-4-carbonitrile
CAS 956778-58-8C12H12FN5
3-Amino-5-(4-fluoro-3-methylanilino)-1-methyl-1H-pyrazole-4-carbonitrile chemical structure, C12H12FN5, CAS 956778-61-3
3-Amino-5-(4-fluoro-3-methylanilino)-1-methyl-1H-pyrazole-4-carbonitrile
CAS 956778-61-3C12H12FN5
N'-[4-Cyano-3-(4-fluoro-3-methylanilino)-1H-pyrazol-5-yl]-N,N-dimethyliminoformamide chemical structure, C14H15FN6, CAS 1106699-25-5
N'-[4-Cyano-3-(4-fluoro-3-methylanilino)-1H-pyrazol-5-yl]-N,N-dimethyliminoformamide
CAS 1106699-25-5C14H15FN6
N-(3-Chlorophenyl)-4-nitro-1H-pyrazol-5-amine chemical structure, C9H7ClN4O2, CAS 400079-85-8
N-(3-Chlorophenyl)-4-nitro-1H-pyrazol-5-amine
CAS 400079-85-8C9H7ClN4O2
Ethyl 3-methyl-5-(phenylamino)-1H-pyrazole-4-carboxylate chemical structure, C13H15N3O2, CAS 4501-60-4
Ethyl 3-methyl-5-(phenylamino)-1H-pyrazole-4-carboxylate
CAS 4501-60-4C13H15N3O2
3-Amino-5-(phenylamino)-1H-pyrazole-4-carbonitrile chemical structure, C10H9N5, CAS 130224-42-9
3-Amino-5-(phenylamino)-1H-pyrazole-4-carbonitrile
CAS 130224-42-9C10H9N5
5-Amino-3-((4-methoxyphenyl)amino)-1H-pyrazole-4-carbonitrile chemical structure, C11H11N5O, CAS 112606-39-0
5-Amino-3-((4-methoxyphenyl)amino)-1H-pyrazole-4-carbonitrile
CAS 112606-39-0C11H11N5O
1,3-Dimethyl-5-{[4-(trifluoromethyl)phenyl]amino}-1H-pyrazole-4-carbonitrile chemical structure, C13H11F3N4, CAS 1027902-03-9
1,3-Dimethyl-5-{[4-(trifluoromethyl)phenyl]amino}-1H-pyrazole-4-carbonitrile
CAS 1027902-03-9C13H11F3N4
1H-Pyrazole-4-carbonitrile, 3-amino-5-[(3-methoxyphenyl)amino]- chemical structure, C11H11N5O, CAS 170464-97-8
1H-Pyrazole-4-carbonitrile, 3-amino-5-[(3-methoxyphenyl)amino]-
CAS 170464-97-8C11H11N5O
N3-phenyl-1H-pyrazole-3,5-diamine chemical structure, C9H10N4, CAS 16945-71-4
N3-phenyl-1H-pyrazole-3,5-diamine
CAS 16945-71-4C9H10N4
5-Anilino-3-methyl-4-pyrazolecarboxylic acid chemical structure, C11H11N3O2, CAS 57861-20-8
5-Anilino-3-methyl-4-pyrazolecarboxylic acid
CAS 57861-20-8C11H11N3O2