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Murcko scaffold

Ring system with 4 rings and 23 atoms

138 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
138
With full pages
1
Scaffold SMILES

O=C(Nc1nc(-c2cc3ccccc3o2)cs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc(-c2cc3ccccc3o2)cs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 138 chemicals

N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-4-(dimethylsulfamoyl)benzamide chemical structure, C20H17N3O4S2, CAS 716365-26-3
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-4-(dimethylsulfamoyl)benzamide
CAS 716365-26-3C20H17N3O4S2
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-4-fluorobenzamide chemical structure, C18H11FN2O2S, CAS 941918-49-6
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-4-fluorobenzamide
CAS 941918-49-6C18H11FN2O2S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3-fluorobenzamide chemical structure, C18H11FN2O2S, CAS 941998-49-8
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3-fluorobenzamide
CAS 941998-49-8C18H11FN2O2S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide chemical structure, C20H16N2O4S, CAS 941961-89-3
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide
CAS 941961-89-3C20H16N2O4S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,4,5-trimethoxybenzamide chemical structure, C21H18N2O5S, CAS 941918-51-0
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,4,5-trimethoxybenzamide
CAS 941918-51-0C21H18N2O5S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,4-dimethoxybenzamide chemical structure, C20H16N2O4S, CAS 941961-91-7
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-3,4-dimethoxybenzamide
CAS 941961-91-7C20H16N2O4S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2-fluorobenzamide chemical structure, C18H11FN2O2S, CAS 941892-72-4
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2-fluorobenzamide
CAS 941892-72-4C18H11FN2O2S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2,6-difluorobenzamide chemical structure, C18H10F2N2O2S, CAS 941918-55-4
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2,6-difluorobenzamide
CAS 941918-55-4C18H10F2N2O2S
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2,3-dimethoxybenzamide chemical structure, C20H16N2O4S, CAS 941961-95-1
N-[4-(1-Benzofuran-2-yl)-1,3-thiazol-2-yl]-2,3-dimethoxybenzamide
CAS 941961-95-1C20H16N2O4S
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-2-(methylsulfonyl)benzamide chemical structure, C19H14N2O4S2, CAS 941998-57-8
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-2-(methylsulfonyl)benzamide
CAS 941998-57-8C19H14N2O4S2
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-3-(methylsulfonyl)benzamide chemical structure, C19H14N2O4S2, CAS 923367-94-6
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-3-(methylsulfonyl)benzamide
CAS 923367-94-6C19H14N2O4S2
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-4-(methylsulfonyl)benzamide chemical structure, C19H14N2O4S2, CAS 941961-97-3
N-(4-(Benzofuran-2-yl)thiazol-2-yl)-4-(methylsulfonyl)benzamide
CAS 941961-97-3C19H14N2O4S2
N-[4-(7-Ethoxy-1-benzofuran-2-yl)-1,3-thiazol-2-yl]-2-(methylsulfanyl)benzamide chemical structure, C21H18N2O3S2, CAS 921871-43-4
N-[4-(7-Ethoxy-1-benzofuran-2-yl)-1,3-thiazol-2-yl]-2-(methylsulfanyl)benzamide
CAS 921871-43-4C21H18N2O3S2
4-[Bis(2-methylpropyl)sulfamoyl]-N-[4-(7-ethoxy-1-benzofuran-2-yl)-1,3-thiazol-2-yl]benzamide chemical structure, C28H33N3O5S2, CAS 941971-15-9
4-[Bis(2-methylpropyl)sulfamoyl]-N-[4-(7-ethoxy-1-benzofuran-2-yl)-1,3-thiazol-2-yl]benzamide
CAS 941971-15-9C28H33N3O5S2
4-Chloro-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C19H13ClN2O3S, CAS 921550-07-4
4-Chloro-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921550-07-4C19H13ClN2O3S
4-(N,N-Diethylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C23H23N3O5S2, CAS 921565-78-8
4-(N,N-Diethylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921565-78-8C23H23N3O5S2
3,4,5-Trimethoxy-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C22H20N2O6S, CAS 921869-41-2
3,4,5-Trimethoxy-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921869-41-2C22H20N2O6S
4-(N,N-Dimethylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C21H19N3O5S2, CAS 921796-46-5
4-(N,N-Dimethylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921796-46-5C21H19N3O5S2
4-(N,N-Dipropylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C25H27N3O5S2, CAS 921550-55-2
4-(N,N-Dipropylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921550-55-2C25H27N3O5S2
4-Cyano-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C20H13N3O3S, CAS 921566-16-7
4-Cyano-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921566-16-7C20H13N3O3S
4-(N,N-Diisobutylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C27H31N3O5S2, CAS 921566-56-5
4-(N,N-Diisobutylsulfamoyl)-N-(4-(7-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921566-56-5C27H31N3O5S2
Methyl 4-((4-(6-methoxybenzofuran-2-yl)thiazol-2-yl)carbamoyl)benzoate chemical structure, C21H16N2O5S, CAS 946305-51-7
Methyl 4-((4-(6-methoxybenzofuran-2-yl)thiazol-2-yl)carbamoyl)benzoate
CAS 946305-51-7C21H16N2O5S
2,5-Dimethoxy-N-(4-(5-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C21H18N2O5S, CAS 946312-52-3
2,5-Dimethoxy-N-(4-(5-methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 946312-52-3C21H18N2O5S
N-(4-(7-Methoxybenzofuran-2-yl)thiazol-2-yl)benzamide chemical structure, C19H14N2O3S, CAS 921565-62-0
N-(4-(7-Methoxybenzofuran-2-yl)thiazol-2-yl)benzamide
CAS 921565-62-0C19H14N2O3S