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Murcko scaffold

Ring system with 4 rings and 23 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
4
With full pages
1
Scaffold SMILES

c1ccc(Nc2nc3cc(Oc4ccncc4)ccc3[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc3cc(Oc4ccncc4)ccc3[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

4-({2-[(4-Bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide chemical structure, C21H18BrN5O2, CAS 611213-70-8
4-({2-[(4-Bromophenyl)(methyl)amino]-1H-1,3-benzodiazol-5-yl}oxy)-N-methylpyridine-2-carboxamide
CAS 611213-70-8C21H18BrN5O2
4-((2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-3H-benzimidazol-5-yl)oxy)-N-methyl-pyridine-2-carboxamide chemical structure, C21H15ClF3N5O2, CAS 611212-56-7
4-((2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-3H-benzimidazol-5-yl)oxy)-N-methyl-pyridine-2-carboxamide
CAS 611212-56-7C21H15ClF3N5O2
(4-Chloro-3-trifluoromethyl-phenyl)-[5-(pyridin-4-yloxy)-1H-benzimidazol-2-yl]-amine chemical structure, C19H12ClF3N4O, CAS 769959-89-9
(4-Chloro-3-trifluoromethyl-phenyl)-[5-(pyridin-4-yloxy)-1H-benzimidazol-2-yl]-amine
CAS 769959-89-9C19H12ClF3N4O
Chz868 chemical structure, C22H19F2N5O2, CAS 1895895-38-1
Chz868
CAS 1895895-38-1C22H19F2N5O2