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Murcko scaffold

Ring system with 4 rings and 25 atoms

146 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 146
With full pages: 10

Scaffold SMILES

O=c1nc2sc(=Cc3ccccc3)c(=O)n2nc1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1nc2sc(=Cc3ccccc3)c(=O)n2nc1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 146 chemicals

[4-[(E)-(6-Benzyl-3,7-dioxo-[1,3]thiazolo[3,2-b][1,2,4]triazin-2-ylidene)methyl]-2-ethoxyphenyl] acetate chemical structure, C23H19N3O5S, CAS 487019-56-7

[4-[(E)-(6-Benzyl-3,7-dioxo-[1,3]thiazolo[3,2-b][1,2,4]triazin-2-ylidene)methyl]-2-ethoxyphenyl] acetate

CAS 487019-56-7C₂₃H₁₉N₃O₅S

4-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]-2-methoxyphenyl acetate chemical structure, C22H17N3O5S, CAS 463959-55-9

4-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-B][1,2,4]triazin-2(3H)-ylidene)methyl]-2-methoxyphenyl acetate

CAS 463959-55-9C₂₂H₁₇N₃O₅S

2-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate chemical structure, C21H15N3O4S, CAS 463959-75-3

2-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate

CAS 463959-75-3C₂₁H₁₅N₃O₄S

(2Z)-6-Benzyl-2-[(2-methoxyphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione chemical structure, C20H15N3O3S, CAS 606954-30-7

(2Z)-6-Benzyl-2-[(2-methoxyphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione

CAS 606954-30-7C₂₀H₁₅N₃O₃S

Methyl 4-[(E)-(6-benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]benzoate chemical structure, C21H15N3O4S, CAS 384368-17-6

Methyl 4-[(E)-(6-benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]benzoate

CAS 384368-17-6C₂₁H₁₅N₃O₄S

(2E)-6-Benzyl-2-[4-(diethylamino)benzylidene]-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H22N4O2S, CAS 463364-64-9

(2E)-6-Benzyl-2-[4-(diethylamino)benzylidene]-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 463364-64-9C₂₃H₂₂N₄O₂S

3-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate chemical structure, C21H15N3O4S, CAS 606955-09-3

3-[(Z)-(6-Benzyl-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene)methyl]phenyl acetate

CAS 606955-09-3C₂₁H₁₅N₃O₄S

(2Z)-6-Benzyl-2-(2,5-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H17N3O4S, CAS 606955-43-5

(2Z)-6-Benzyl-2-(2,5-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 606955-43-5C₂₁H₁₇N₃O₄S

(2Z)-6-Benzyl-2-(3,4,5-trimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C22H19N3O5S, CAS 606955-65-1

(2Z)-6-Benzyl-2-(3,4,5-trimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 606955-65-1C₂₂H₁₉N₃O₅S

(2Z)-6-Benzyl-2-(3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C20H15N3O3S, CAS 606954-37-4

(2Z)-6-Benzyl-2-(3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 606954-37-4C₂₀H₁₅N₃O₃S

(2Z)-6-Benzyl-2-(4-isopropylbenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione chemical structure, C22H19N3O2S, CAS 463364-58-1

(2Z)-6-Benzyl-2-(4-isopropylbenzylidene)-7H-(1,3)thiazolo(3,2-B)(1,2,4)triazine-3,7(2H)-dione

CAS 463364-58-1C₂₂H₁₉N₃O₂S

(2Z)-6-Benzyl-2-(4-ethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H17N3O3S, CAS 638133-68-3

(2Z)-6-Benzyl-2-(4-ethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638133-68-3C₂₁H₁₇N₃O₃S

(2Z)-6-Benzyl-2-(4-ethoxy-3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C22H19N3O4S, CAS 606955-32-2

(2Z)-6-Benzyl-2-(4-ethoxy-3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 606955-32-2C₂₂H₁₉N₃O₄S

(2Z)-6-(2-Chlorobenzyl)-2-(4-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C20H14ClN3O3S, CAS 636991-25-8

(2Z)-6-(2-Chlorobenzyl)-2-(4-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 636991-25-8C₂₀H₁₄ClN₃O₃S

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(2,3-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H21N3O6S, CAS 638133-52-5

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(2,3-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638133-52-5C₂₃H₂₁N₃O₆S

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(4-ethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C23H21N3O5S, CAS 638133-56-9

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(4-ethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638133-56-9C₂₃H₂₁N₃O₅S

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C22H19N3O5S, CAS 638133-57-0

(2Z)-6-(3,4-Dimethoxybenzyl)-2-(3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638133-57-0C₂₂H₁₉N₃O₅S

(2Z)-6-(2-Chlorobenzyl)-2-[4-(dimethylamino)benzylidene]-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H17ClN4O2S, CAS 638134-52-8

(2Z)-6-(2-Chlorobenzyl)-2-[4-(dimethylamino)benzylidene]-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-52-8C₂₁H₁₇ClN₄O₂S

(2Z)-2-Benzylidene-6-(2-chlorobenzyl)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C19H12ClN3O2S, CAS 638134-53-9

(2Z)-2-Benzylidene-6-(2-chlorobenzyl)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-53-9C₁₉H₁₂ClN₃O₂S

(2Z)-6-(2-Chlorobenzyl)-2-(3,4-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H16ClN3O4S, CAS 638134-54-0

(2Z)-6-(2-Chlorobenzyl)-2-(3,4-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-54-0C₂₁H₁₆ClN₃O₄S

(2Z)-6-(2-Chlorobenzyl)-2-(2-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C20H14ClN3O3S, CAS 638134-57-3

(2Z)-6-(2-Chlorobenzyl)-2-(2-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-57-3C₂₀H₁₄ClN₃O₃S

Methyl 4-{(Z)-[6-(2-chlorobenzyl)-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene]methyl}benzoate chemical structure, C21H14ClN3O4S, CAS 638134-65-3

Methyl 4-{(Z)-[6-(2-chlorobenzyl)-3,7-dioxo-7H-[1,3]thiazolo[3,2-b][1,2,4]triazin-2(3H)-ylidene]methyl}benzoate

CAS 638134-65-3C₂₁H₁₄ClN₃O₄S

(2Z)-6-(2-Chlorobenzyl)-2-(2,3-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C21H16ClN3O4S, CAS 638134-67-5

(2Z)-6-(2-Chlorobenzyl)-2-(2,3-dimethoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-67-5C₂₁H₁₆ClN₃O₄S

(2Z)-6-(2-Chlorobenzyl)-2-(4-ethoxy-3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione chemical structure, C22H18ClN3O4S, CAS 638134-69-7

(2Z)-6-(2-Chlorobenzyl)-2-(4-ethoxy-3-methoxybenzylidene)-7H-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7(2H)-dione

CAS 638134-69-7C₂₂H₁₈ClN₃O₄S