Murcko scaffold
Benzisothiazole scaffold
560 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 560
- With full pages
- 41
Scaffold SMILES
c1ccc2sncc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 385 to 432 of 560 chemicals
![7-Bromo-4-chlorobenzo[D]isothiazole chemical structure, C7H3BrClNS, CAS 29102-97-4](/s/NMRQEHYSMQRTBW-UHFFFAOYSA-N.svg)
7-Bromo-4-chlorobenzo[D]isothiazole
CAS 29102-97-4C7H3BrClNS
3-Methyl-5-prop-2-enoxy-1,2-benzothiazole
CAS 75608-08-1C11H11NOS
![N-Methylbenzo[d]isothiazol-6-amine chemical structure, C8H8N2S, CAS 2089325-33-5](/s/NIILEHPXPMUSSF-UHFFFAOYSA-N.svg)
N-Methylbenzo[d]isothiazol-6-amine
CAS 2089325-33-5C8H8N2S
![6-(Trifluoromethyl)benzo[d]isothiazole chemical structure, C8H4F3NS, CAS 2383624-72-2](/s/SGKCOVMEUOKDIL-UHFFFAOYSA-N.svg)
6-(Trifluoromethyl)benzo[d]isothiazole
CAS 2383624-72-2C8H4F3NS
![7-(Chloromethyl)benzo[d]isothiazole chemical structure, C8H6ClNS, CAS 2021538-99-6](/s/ZVCMSUWVQPCUMG-UHFFFAOYSA-N.svg)
7-(Chloromethyl)benzo[d]isothiazole
CAS 2021538-99-6C8H6ClNS
![Methyl benzo[d]isothiazole-4-carboxylate chemical structure, C9H7NO2S, CAS 1378676-29-9](/s/BKDHKSWMVQNAAN-UHFFFAOYSA-N.svg)
Methyl benzo[d]isothiazole-4-carboxylate
CAS 1378676-29-9C9H7NO2S
![Ethyl benzo[d]isothiazole-6-carboxylate chemical structure, C10H9NO2S, CAS 2089311-01-1](/s/ZWGPUXKOFCSLDN-UHFFFAOYSA-N.svg)
Ethyl benzo[d]isothiazole-6-carboxylate
CAS 2089311-01-1C10H9NO2S
![Methyl benzo[d]isothiazole-7-carboxylate chemical structure, C9H7NO2S, CAS 2029305-12-0](/s/NEGXLTSVSGMHHG-UHFFFAOYSA-N.svg)
Methyl benzo[d]isothiazole-7-carboxylate
CAS 2029305-12-0C9H7NO2S
![Ethyl benzo[d]isothiazole-7-carboxylate chemical structure, C10H9NO2S, CAS 2025499-21-0](/s/LWUDGPXYJCGOLG-UHFFFAOYSA-N.svg)
Ethyl benzo[d]isothiazole-7-carboxylate
CAS 2025499-21-0C10H9NO2S
![Benzo[d]isothiazol-5-ylboronic acid chemical structure, C7H6BNO2S, CAS 2086293-74-3](/s/YIIKQGLBPGMCDL-UHFFFAOYSA-N.svg)
Benzo[d]isothiazol-5-ylboronic acid
CAS 2086293-74-3C7H6BNO2S
![Benzo[d]isothiazol-7-ylboronic acid chemical structure, C7H6BNO2S, CAS 2246672-25-1](/s/UBSCJBLVSWUKRA-UHFFFAOYSA-N.svg)
Benzo[d]isothiazol-7-ylboronic acid
CAS 2246672-25-1C7H6BNO2S
![5-Bromo-7-methylbenzo[D]isothiazole chemical structure, C8H6BrNS, CAS 1369493-97-9](/s/XNNPMJMWKKPDDQ-UHFFFAOYSA-N.svg)
5-Bromo-7-methylbenzo[D]isothiazole
CAS 1369493-97-9C8H6BrNS
Methyl 6-cyano-1,2-benzothiazole-3-carboxylate
CAS 1989672-61-8C10H6N2O2S
(1,2-Benzothiazol-3-yl)methanamine hydrochloride
CAS 73437-28-2C8H9ClN2S
3-(2-Bromoethyl)-1,2-benzothiazole
CAS 1935987-70-4C9H8BrNS
1,2-Benzisothiazole-3-methanol
CAS 1823873-23-9C8H7NOS
3-Fluoro-1,2-benzothiazole
CAS 2742653-53-6C7H4FNS
![4-Methoxybenzo[d]isothiazole-3-carboxylic acid chemical structure, C9H7NO3S, CAS 1384079-93-9](/s/LBPJGQMNHOVIAP-UHFFFAOYSA-N.svg)
4-Methoxybenzo[d]isothiazole-3-carboxylic acid
CAS 1384079-93-9C9H7NO3S
1,2-Benzothiazole-3-carbonyl azide
CAS 1824318-75-3C8H4N4OS
6-Chloro-4-methyl-1,2-benzothiazole
CAS 1427446-16-9C8H6ClNS
![4-Bromo-6-methylbenzo[d]isothiazole chemical structure, C8H6BrNS, CAS 1427446-45-4](/s/SBQDWKIXZOXIAF-UHFFFAOYSA-N.svg)
4-Bromo-6-methylbenzo[d]isothiazole
CAS 1427446-45-4C8H6BrNS
5-Bromo-6-methyl-1,2-benzothiazole
CAS 1427403-77-7C8H6BrNS
Methyl 7-methyl-1,2-benzothiazole-5-carboxylate
CAS 1427368-56-6C10H9NO2S
4-Chloro-5-fluoro-1,2-benzothiazole
CAS 1427452-25-2C7H3ClFNS
- 6-Bromo-7-fluoro-1,2-benzothiazole1427328-10-6C7H3BrFNS
- 4-Bromo-6-chloro-1,2-benzothiazole1427419-08-6C7H3BrClNS
- 6-Bromo-7-chloro-1,2-benzothiazole1427447-75-3C7H3BrClNS
- 5-Bromo-6-methoxy-1,2-benzisothiazole1427419-31-5C8H6BrNOS
- 6-Bromo-5-methoxy-1,2-benzisothiazole1427404-73-6C8H6BrNOS
- 7-Bromo-5-methoxy-1,2-benzothiazole1427447-86-6C8H6BrNOS
- 6-Chloro-1,2-benzothiazole-3-carbaldehyde1823920-56-4C8H4ClNOS
- 6-Fluoro-1,2-benzothiazole-3-carbaldehyde1823908-98-0C8H4FNOS
- N-(1,2-Benzothiazol-5-yl)prop-2-enamide2185980-50-9C10H8N2OS
- N-[2-(1,2-Benzothiazol-3-yl)ethyl]prop-2-enamide2176843-65-3C12H12N2OS
- (5-Chloro-1,2-benzothiazol-3-yl)methanamine hydrochloride73437-35-1C8H8Cl2N2S
- 6-Bromo-3-chloro-5-fluoro-1,2-benzothiazole2137980-90-4C7H2BrClFNS
- 7-Methylbenzo[d]isothiazol-4-ol693220-44-9C8H7NOS
- 1,2-Benzisothiazol-4-ol, 7-amino-67322-83-2C7H6N2OS
- 6-Hydroxybenzo[d]isothiazole-3-carboxylic acid932702-33-5C8H5NO3S
- Benzo[d]isothiazol-4-ol67982-15-4C7H5NOS
- 7-Fluorobenzo[d]isothiazol-4-ol934180-40-2C7H4FNOS
- 3-Aminobenzo[d]isothiazol-6-ol613262-24-1C7H6N2OS
- 1,2-Benzisothiazol-6-ol934180-38-8C7H5NOS
- 3-Methylbenzo[d]isothiazol-6-ol192443-26-8C8H7NOS
- 3-Methylbenzo[d]isothiazol-4-ol1187732-47-3C8H7NOS
- 4-Bromo-3-chloro-1,2-benzothiazole1809150-02-4C7H3BrClNS
- 7-Bromo-3-chloro-1,2-benzothiazole2138254-24-5C7H3BrClNS
- 3-Chlorobenzo[d]isothiazol-6-amine2305621-31-0C7H5ClN2S
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals