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Murcko scaffold

Ring system with 4 rings and 25 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
13
With full pages
2
Scaffold SMILES

O=C1N=c2ccccc2=C1c1cn(NC(=O)c2ccccc2)c(=S)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1N=c2ccccc2=C1c1cn(NC(=O)c2ccccc2)c(=S)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

(E)-2-Chloro-N-(5-(5-methyl-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzamide chemical structure, C19H12ClN3O3S2, CAS 301304-71-2
(E)-2-Chloro-N-(5-(5-methyl-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzamide
CAS 301304-71-2C19H12ClN3O3S2
N-[(5Z)-4-Oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide chemical structure, C18H11N3O3S2, CAS 5534-97-4
N-[(5Z)-4-Oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
CAS 5534-97-4C18H11N3O3S2
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-chlorobenzamide chemical structure, C18H9BrClN3O3S2, CAS 301689-82-7
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-chlorobenzamide
CAS 301689-82-7C18H9BrClN3O3S2
2-Methyl-N-[(5Z)-4-oxo-5-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-thioxo-1,3-thiazolidin-3-yl]benzamide chemical structure, C19H13N3O3S2, CAS 301691-80-5
2-Methyl-N-[(5Z)-4-oxo-5-(2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-thioxo-1,3-thiazolidin-3-yl]benzamide
CAS 301691-80-5C19H13N3O3S2
4-Methyl-N-[(5Z)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide chemical structure, C19H13N3O3S2, CAS 302576-06-3
4-Methyl-N-[(5Z)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
CAS 302576-06-3C19H13N3O3S2
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-4-methylbenzamide chemical structure, C19H12BrN3O3S2, CAS 302576-05-2
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-4-methylbenzamide
CAS 302576-05-2C19H12BrN3O3S2
(Z)-N-(5-(5-Bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzamide chemical structure, C18H10BrN3O3S2, CAS 301223-63-2
(Z)-N-(5-(5-Bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)benzamide
CAS 301223-63-2C18H10BrN3O3S2
(Z)-2-Chloro-N-(4-oxo-5-(2-oxoindolin-3-ylidene)-2-thioxothiazolidin-3-yl)benzamide chemical structure, C18H10ClN3O3S2, CAS 300818-98-8
(Z)-2-Chloro-N-(4-oxo-5-(2-oxoindolin-3-ylidene)-2-thioxothiazolidin-3-yl)benzamide
CAS 300818-98-8C18H10ClN3O3S2
4-Hydroxy-3-methoxy-N-[(5E)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide chemical structure, C19H13N3O5S2, CAS 301227-53-2
4-Hydroxy-3-methoxy-N-[(5E)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
CAS 301227-53-2C19H13N3O5S2
(E)-N-(5-(5-Bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)-4-hydroxy-3-methoxybenzamide chemical structure, C19H12BrN3O5S2, CAS 301227-54-3
(E)-N-(5-(5-Bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)-4-hydroxy-3-methoxybenzamide
CAS 301227-54-3C19H12BrN3O5S2
N-[(5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-2-nitrobenzamide chemical structure, C18H9BrN4O5S2, CAS 301308-60-1
N-[(5Z)-5-(5-Bromo-2-oxo-1H-indol-3-ylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-2-nitrobenzamide
CAS 301308-60-1C18H9BrN4O5S2
3-Hydroxy-N-[(5Z)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide chemical structure, C18H11N3O4S2, CAS 303056-90-8
3-Hydroxy-N-[(5Z)-4-oxo-5-(2-oxo-1H-indol-3-ylidene)-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
CAS 303056-90-8C18H11N3O4S2
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-hydroxybenzamide chemical structure, C18H10BrN3O4S2, CAS 303056-91-9
N-[(5Z)-5-(5-Bromo-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-hydroxybenzamide
CAS 303056-91-9C18H10BrN3O4S2