Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 22 atoms

40 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 40
With full pages: 1

Scaffold SMILES

c1ccc(CSc2nnc(-c3c[nH]c4ccccc34)[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(CSc2nnc(-c3c[nH]c4ccccc34)[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

3-(4-Ethyl-5-((4-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H17FN4S, CAS 830349-81-0

3-(4-Ethyl-5-((4-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 830349-81-0C₁₉H₁₇FN₄S

3-(5-((2-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H15ClN4S, CAS 831249-79-7

3-(5-((2-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 831249-79-7C₁₈H₁₅ClN₄S

3-(5-{[(3-Fluorophenyl)methyl]sulfanyl}-4-hexyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C23H25FN4S, CAS 568560-96-3

3-(5-{[(3-Fluorophenyl)methyl]sulfanyl}-4-hexyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 568560-96-3C₂₃H₂₅FN₄S

3-(5-(Benzylthio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H16N4S, CAS 831184-35-1

3-(5-(Benzylthio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 831184-35-1C₁₈H₁₆N₄S

3-(4-Ethyl-5-((3-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H17N5O2S, CAS 852144-26-4

3-(4-Ethyl-5-((3-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852144-26-4C₁₉H₁₇N₅O₂S

3-(5-((3-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H15FN4S, CAS 852143-24-9

3-(5-((3-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852143-24-9C₁₈H₁₅FN₄S

3-(5-((4-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H15FN4S, CAS 852143-25-0

3-(5-((4-Fluorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852143-25-0C₁₈H₁₅FN₄S

3-{4-Methyl-5-[(1-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}-1H-indole chemical structure, C19H18N4S, CAS 863002-08-8

3-{4-Methyl-5-[(1-phenylethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}-1H-indole

CAS 863002-08-8C₁₉H₁₈N₄S

3-(4-Methyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H18N4S, CAS 852143-26-1

3-(4-Methyl-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852143-26-1C₁₉H₁₈N₄S

3-(5-((4-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H15ClN4S, CAS 863002-09-9

3-(5-((4-Chlorobenzyl)thio)-4-methyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 863002-09-9C₁₈H₁₅ClN₄S

3-(4-Methyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C18H15N5O2S, CAS 852143-27-2

3-(4-Methyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852143-27-2C₁₈H₁₅N₅O₂S

3-(4-(2-Methoxyethyl)-5-((4-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H19F3N4OS, CAS 946377-07-7

3-(4-(2-Methoxyethyl)-5-((4-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946377-07-7C₂₁H₁₉F₃N₄OS

3-(5-(Benzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H18N4S, CAS 852144-22-0

3-(5-(Benzylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852144-22-0C₁₉H₁₈N₄S

3-(4-(2-Methoxyethyl)-5-((3-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C20H19N5O3S, CAS 852145-24-5

3-(4-(2-Methoxyethyl)-5-((3-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-24-5C₂₀H₁₉N₅O₃S

3-(5-((2,5-Dimethylbenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H22N4S, CAS 946376-99-4

3-(5-((2,5-Dimethylbenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946376-99-4C₂₁H₂₂N₄S

3-(5-((3-Fluorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C20H19FN4OS, CAS 852145-15-4

3-(5-((3-Fluorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-15-4C₂₀H₁₉FN₄OS

3-(5-((3-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H17ClN4S, CAS 896352-51-5

3-(5-((3-Chlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 896352-51-5C₁₉H₁₇ClN₄S

3-(4-(2-Methoxyethyl)-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H22N4OS, CAS 852145-17-6

3-(4-(2-Methoxyethyl)-5-((2-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-17-6C₂₁H₂₂N₄OS

3-(4-(2-Methoxyethyl)-5-((3-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H22N4OS, CAS 852145-19-8

3-(4-(2-Methoxyethyl)-5-((3-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-19-8C₂₁H₂₂N₄OS

3-(5-((2,5-Dimethylbenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C22H24N4OS, CAS 946205-88-5

3-(5-((2,5-Dimethylbenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 946205-88-5C₂₂H₂₄N₄OS

3-(5-((4-Fluorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C20H19FN4OS, CAS 852145-16-5

3-(5-((4-Fluorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-16-5C₂₀H₁₉FN₄OS

3-(5-((3,4-Dichlorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C20H18Cl2N4OS, CAS 896352-64-0

3-(5-((3,4-Dichlorobenzyl)thio)-4-(2-methoxyethyl)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 896352-64-0C₂₀H₁₈Cl₂N₄OS

3-(4-(2-Methoxyethyl)-5-((4-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C21H22N4OS, CAS 852145-20-1

3-(4-(2-Methoxyethyl)-5-((4-methylbenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852145-20-1C₂₁H₂₂N₄OS

3-(4-Ethyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole chemical structure, C19H17N5O2S, CAS 852144-23-1

3-(4-Ethyl-5-((4-nitrobenzyl)thio)-4H-1,2,4-triazol-3-yl)-1H-indole

CAS 852144-23-1C₁₉H₁₇N₅O₂S