CompoundList
Sign in
Murcko scaffold

Pyrimidine scaffold

19,000 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
6
Chemicals
19,000
With full pages
2,066
Scaffold SMILES

c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Pyrimidine page
Murcko scaffold c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,873 to 1,920 of 19,000 chemicals

2-(Dimethylamino)-4-(propan-2-yl)pyrimidine-5-carboxylic acid chemical structure, C10H15N3O2, CAS 180283-76-5
2-(Dimethylamino)-4-(propan-2-yl)pyrimidine-5-carboxylic acid
CAS 180283-76-5C10H15N3O2
4-(Isopropylamino)-2-(methylthio)pyrimidine-5-carbaldehyde chemical structure, C9H13N3OS, CAS 321690-73-7
4-(Isopropylamino)-2-(methylthio)pyrimidine-5-carbaldehyde
CAS 321690-73-7C9H13N3OS
2,4-Pentadiyn-1-ol, 5-[4-methyl-2-(methylthio)-5-pyrimidinyl]- chemical structure, C11H10N2OS, CAS 157664-66-9
2,4-Pentadiyn-1-ol, 5-[4-methyl-2-(methylthio)-5-pyrimidinyl]-
CAS 157664-66-9C11H10N2OS
5-Bromo-2-chloro-N-methylpyrimidin-4-amine chemical structure, C5H5BrClN3, CAS 205672-24-8
5-Bromo-2-chloro-N-methylpyrimidin-4-amine
CAS 205672-24-8C5H5BrClN3
4-[(2-Methylpropyl)amino]-2-(methylthio)-5-pyrimidinemethanol chemical structure, C10H17N3OS, CAS 1082462-41-6
4-[(2-Methylpropyl)amino]-2-(methylthio)-5-pyrimidinemethanol
CAS 1082462-41-6C10H17N3OS
2,6-Dimethoxy-5-nitropyrimidine-4-carbonyl chloride chemical structure, C7H6ClN3O5, CAS 226559-54-2
2,6-Dimethoxy-5-nitropyrimidine-4-carbonyl chloride
CAS 226559-54-2C7H6ClN3O5
4-Pyrimidinamine, 5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]- chemical structure, C10H20FN3OSi2, CAS 111878-21-8
4-Pyrimidinamine, 5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-
CAS 111878-21-8C10H20FN3OSi2
Pyrimidine, 2-[(difluoromethyl)thio]- chemical structure, C5H4F2N2S, CAS 129549-96-8
Pyrimidine, 2-[(difluoromethyl)thio]-
CAS 129549-96-8C5H4F2N2S
4-(Ethylamino)-2-(methylthio)pyrimidine-5-carbaldehyde chemical structure, C8H11N3OS, CAS 185040-35-1
4-(Ethylamino)-2-(methylthio)pyrimidine-5-carbaldehyde
CAS 185040-35-1C8H11N3OS
2,4-Bis(trifluoromethyl)pyrimidine-5-carbonyl chloride chemical structure, C7HClF6N2O, CAS 188781-16-0
2,4-Bis(trifluoromethyl)pyrimidine-5-carbonyl chloride
CAS 188781-16-0C7HClF6N2O
(E)-2-(Pyrimidin-4-yl)acetaldehyde oxime chemical structure, C6H7N3O, CAS 179009-38-2
(E)-2-(Pyrimidin-4-yl)acetaldehyde oxime
CAS 179009-38-2C6H7N3O
Methyl (E)-3-(2-methoxy-5-pyrimidinyl)acrylate chemical structure, C9H10N2O3, CAS 107166-90-5
Methyl (E)-3-(2-methoxy-5-pyrimidinyl)acrylate
CAS 107166-90-5C9H10N2O3
Ethyl alpha,alpha-difluoro-2-pyrimidineacetate chemical structure, C8H8F2N2O2, CAS 294181-98-9
Ethyl alpha,alpha-difluoro-2-pyrimidineacetate
CAS 294181-98-9C8H8F2N2O2
2-Chloro-4-ethyl-5-pyrimidinecarbonyl chloride chemical structure, C7H6Cl2N2O, CAS 306960-72-5
2-Chloro-4-ethyl-5-pyrimidinecarbonyl chloride
CAS 306960-72-5C7H6Cl2N2O
Heteromine H chemical structure, C8H13N5O2, CAS 116137-80-5
Heteromine H
CAS 116137-80-5C8H13N5O2
2-Chloro-6-(trifluoromethyl)pyrimidine-4-carboxylic acid chemical structure, C6H2ClF3N2O2, CAS 306960-80-5
2-Chloro-6-(trifluoromethyl)pyrimidine-4-carboxylic acid
CAS 306960-80-5C6H2ClF3N2O2
Ethyl (e)-3-(4-(ethylamino)-2-(methylthio)pyrimidin-5-yl)acrylate chemical structure, C12H17N3O2S, CAS 211244-85-8
Ethyl (e)-3-(4-(ethylamino)-2-(methylthio)pyrimidin-5-yl)acrylate
CAS 211244-85-8C12H17N3O2S
4-Chloro-2,6-dimethoxy-5-[(trimethylsilyl)ethynyl]pyrimidine chemical structure, C11H15ClN2O2Si, CAS 216979-85-0
4-Chloro-2,6-dimethoxy-5-[(trimethylsilyl)ethynyl]pyrimidine
CAS 216979-85-0C11H15ClN2O2Si
Ethyl 3-[(pyrimidin-2-yl)amino]propanoate chemical structure, C9H13N3O2, CAS 339195-97-0
Ethyl 3-[(pyrimidin-2-yl)amino]propanoate
CAS 339195-97-0C9H13N3O2
6-Chloro-N4-isobutylpyrimidine-4,5-diamine chemical structure, C8H13ClN4, CAS 195252-59-6
6-Chloro-N4-isobutylpyrimidine-4,5-diamine
CAS 195252-59-6C8H13ClN4
5-Amino-2-butyl-6-ethoxypyrimidine-4-carbonitrile chemical structure, C11H16N4O, CAS 342823-94-3
5-Amino-2-butyl-6-ethoxypyrimidine-4-carbonitrile
CAS 342823-94-3C11H16N4O
2-Cyano-4-trifluoromethylpyrimidine-5-carbonyl chloride chemical structure, C7HClF3N3O, CAS 188781-19-3
2-Cyano-4-trifluoromethylpyrimidine-5-carbonyl chloride
CAS 188781-19-3C7HClF3N3O
5-Bromo-2-chloro-N,N-dimethylpyrimidin-4-amine chemical structure, C6H7BrClN3, CAS 57054-86-1
5-Bromo-2-chloro-N,N-dimethylpyrimidin-4-amine
CAS 57054-86-1C6H7BrClN3
Sulfamoyl chloride, [[(4,6-dimethyl-2-pyrimidinyl)amino]carbonyl]- chemical structure, C7H9ClN4O3S, CAS 88078-58-4
Sulfamoyl chloride, [[(4,6-dimethyl-2-pyrimidinyl)amino]carbonyl]-
CAS 88078-58-4C7H9ClN4O3S

Only the first 1,920 are listed here. Use the substructure search to filter further.